ES8604735A1 - Un nuevo procedimiento para la preparacion de pirido-imida- zo-rifamicinas - Google Patents

Un nuevo procedimiento para la preparacion de pirido-imida- zo-rifamicinas

Info

Publication number
ES8604735A1
ES8604735A1 ES547265A ES547265A ES8604735A1 ES 8604735 A1 ES8604735 A1 ES 8604735A1 ES 547265 A ES547265 A ES 547265A ES 547265 A ES547265 A ES 547265A ES 8604735 A1 ES8604735 A1 ES 8604735A1
Authority
ES
Spain
Prior art keywords
rifamicine
pyrido
imidazo
formula
equivs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES547265A
Other languages
English (en)
Other versions
ES547265A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alfa Farmaceutici SpA
Original Assignee
Alfa Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Farmaceutici SpA filed Critical Alfa Farmaceutici SpA
Publication of ES8604735A1 publication Critical patent/ES8604735A1/es
Publication of ES547265A0 publication Critical patent/ES547265A0/es
Expired legal-status Critical Current

Links

Landscapes

  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NUEVO PROCEDIMIENTO PARA LA PREPARACION DE PIRIDO-IMIDAZO-RIFAMICINAS. CONSISTE EN HACER REACCIONAR UN EQUIVALENTE MOLAR DE RIFAMICINA B DE FORMULA (II) CON DE 1 A 9 EQUIVALENTES MOLARES DE UNA 2-AMINOPIRIDINA DE FORMULA (III) Y DE 1 A 4 EQUIVALENTES MOLARES DE UN AGENTE OXIDANTE, PARA OBTENER PIRIDO-IMIDAZO-RIFAMICINAS DE FORMULA (I) DONDE R ES H O ACETILO; R1 Y R2 SON INDEPENDIENTEMENTE H, ALQUILO C 1 A 4, BENCILOXILO, MONO- O DI-(C 1 A 3)-ALQUILAMINO (C 1 A 4)-ALQUILO Y OTROS. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE, A TEMPERATURA ENTRE LA AMBIENTE Y LA DE LA MEZCLA REACCIONAL Y DURANTE UN PERIODO DE TIEMPO COMPRENDIDO ENTRE 10 Y 100 HORAS. SE UTILIZAN PARA COMBATIR INFECCIONES MICROBIANAS DEL TRACTO GASTROINTESTINAL.
ES547265A 1984-09-26 1985-09-25 Un nuevo procedimiento para la preparacion de pirido-imida- zo-rifamicinas Expired ES8604735A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT03581/84A IT1199413B (it) 1984-09-26 1984-09-26 Processo per la preparazione di pirido-imidazo-rifamicine

Publications (2)

Publication Number Publication Date
ES8604735A1 true ES8604735A1 (es) 1986-02-16
ES547265A0 ES547265A0 (es) 1986-02-16

Family

ID=11110114

Family Applications (1)

Application Number Title Priority Date Filing Date
ES547265A Expired ES8604735A1 (es) 1984-09-26 1985-09-25 Un nuevo procedimiento para la preparacion de pirido-imida- zo-rifamicinas

Country Status (10)

Country Link
AR (1) AR243892A1 (es)
AT (1) AT387020B (es)
CA (1) CA1218650A (es)
DK (1) DK161706C (es)
ES (1) ES8604735A1 (es)
FI (1) FI83875C (es)
GR (1) GR852312B (es)
IT (1) IT1199413B (es)
NO (1) NO165107C (es)
PT (1) PT81198B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7902206B2 (en) 2003-11-07 2011-03-08 Alfa Wassermann, S.P.A. Polymorphic forms α, β and γ of rifaximin
ITMI20032144A1 (it) 2003-11-07 2005-05-08 Alfa Wassermann Spa Forme polimorfe di rifaximina, processi per ottenerle e
US7906542B2 (en) 2004-11-04 2011-03-15 Alfa Wassermann, S.P.A. Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin
SI1698630T1 (sl) 2005-03-03 2015-01-30 Alfa Wassermann S.P.A. Nove polimorfne oblike rifaksimina, postopki za njihovo pripravo in njihova uporaba v medicinskih pripravkih
US7709634B2 (en) 2007-09-20 2010-05-04 Apotex Pharmachem Inc. Amorphous form of rifaximin and processes for its preparation
ITBO20120368A1 (it) 2012-07-06 2014-01-07 Alfa Wassermann Spa Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
ES2621557T3 (es) 2014-03-31 2017-07-04 Euticals S.P.A. Mezcla polimórfica de rifaximina y su uso para la preparación de formulaciones sólidas
PT3143027T (pt) 2014-05-12 2019-09-20 Alfasigma Spa Nova forma de cristal solvatado de rifaximina, produção, composições e utilização dos mesmos

Also Published As

Publication number Publication date
GR852312B (es) 1986-01-24
DK161706C (da) 1992-01-20
FI853683A0 (fi) 1985-09-25
PT81198A (en) 1985-10-01
FI853683L (fi) 1986-03-27
NO853771L (no) 1986-04-01
IT1199413B (it) 1988-12-30
ATA279785A (de) 1988-04-15
FI83875C (fi) 1991-09-10
NO165107C (no) 1990-12-27
IT8403581A0 (it) 1984-09-26
DK434985A (da) 1986-03-27
NO165107B (no) 1990-09-17
CA1218650A (en) 1987-03-03
DK434985D0 (da) 1985-09-25
ES547265A0 (es) 1986-02-16
PT81198B (pt) 1987-09-30
FI83875B (fi) 1991-05-31
DK161706B (da) 1991-08-05
AR243892A1 (es) 1993-09-30
AT387020B (de) 1988-11-25

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20051123