ES8604423A1 - Metodo de produccion de composiciones que contienen globulina gamma - Google Patents

Metodo de produccion de composiciones que contienen globulina gamma

Info

Publication number
ES8604423A1
ES8604423A1 ES524890A ES524890A ES8604423A1 ES 8604423 A1 ES8604423 A1 ES 8604423A1 ES 524890 A ES524890 A ES 524890A ES 524890 A ES524890 A ES 524890A ES 8604423 A1 ES8604423 A1 ES 8604423A1
Authority
ES
Spain
Prior art keywords
gamma globulin
concentrate
globulin
ion exchange
exchange resin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES524890A
Other languages
English (en)
Other versions
ES524890A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Baxter Travenol Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23635654&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8604423(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Baxter Travenol Laboratories Inc filed Critical Baxter Travenol Laboratories Inc
Publication of ES8604423A1 publication Critical patent/ES8604423A1/es
Publication of ES524890A0 publication Critical patent/ES524890A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

METODO DE PRODUCCION DE COMPOSICIONES QUE CONTIENEN GLOBULINA GAMMA. COMPRENDE LA ULTRAFILTRACION A UN PH DE 5 A 5,6 Y/O TRATAMIENTO DE UN CONCENTRADO DE GLOBULINA GAMMA QUE CONTIENE MAS DEL 80% DE DICHA GLOBULINA POR PESO DEL TOTAL DE PROTEINA PRESENTE EN EL CONCENTRADO, CON UNA RESINA DE CAMBIO IONICO, INCLUYENDOSE UN ESTABILIZADOR CON UN CONCENTRADO DE GLOBULINA GAMMA DURANTE LA ULTRAFILTRACION Y/O DURANTE EL TRATAMIENTO CON LA RESINA DE CAMBIO IONICO, EN UNA CANTIDAD SUFICIENTE PARA REDUCIR LA ACTIVIDAD ANTICOMPLEMENTARIA DE LA GLOBULINA GAMMA ASI PREPARADA. EL ESTABILIZADOR ES UNA MACROMOLECULA HIDROFILICA, UN POLIOL DE BAJO PESO MOLECULAR, UN POLIETER MACROMOLECULA HIDROFILICA, UN POLIOL DE BAJO PESO MOLECULAR, UN POLIETER, UN POLISACARIDO O POLIMERO VINILICO HIDROFILICO O UN AMINOACIDO.
ES524890A 1982-08-30 1983-08-11 Metodo de produccion de composiciones que contienen globulina gamma Expired ES8604423A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41305982A 1982-08-30 1982-08-30

Publications (2)

Publication Number Publication Date
ES8604423A1 true ES8604423A1 (es) 1986-02-01
ES524890A0 ES524890A0 (es) 1986-02-01

Family

ID=23635654

Family Applications (1)

Application Number Title Priority Date Filing Date
ES524890A Expired ES8604423A1 (es) 1982-08-30 1983-08-11 Metodo de produccion de composiciones que contienen globulina gamma

Country Status (8)

Country Link
EP (1) EP0116571B2 (es)
JP (1) JPH08787B2 (es)
AT (1) ATE66616T1 (es)
CA (1) CA1239584A (es)
DE (1) DE3382394D1 (es)
ES (1) ES8604423A1 (es)
IT (1) IT1169788B (es)
WO (1) WO1984000891A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4439421A (en) * 1982-08-30 1984-03-27 Baxter Travenol Laboratories, Inc. Stabilized gamma globulin concentrate
DE3641115A1 (de) * 1986-12-02 1988-06-16 Lentia Gmbh Verfahren zur herstellung eines intravenoes anwendbaren und in fluessiger form stabilen immunglobulins
ES2184594B1 (es) * 2001-01-17 2004-01-01 Probitas Pharma Sa Procedimiento para la produccion de gammaglobulina g humana inactivada de virus.
JP2005320248A (ja) * 2002-04-22 2005-11-17 Mitsubishi Pharma Corp 免疫グロブリン製剤の製造方法
ES2386972T3 (es) 2006-05-31 2012-09-10 Genzyme Corporation Uso de polisacáridos para la estimulación de la actividad enzimática

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1064396A (en) * 1975-02-18 1979-10-16 Myer L. Coval Fractional precipitation of gamma globulin with polyethylene glycol
JPS5347515A (en) * 1976-10-13 1978-04-28 Green Cross Corp:The Gamma-globulin pharmaceutical preparation for intravenous injection
US4136094A (en) * 1977-08-31 1979-01-23 The Regents Of The University Of Minnesota Preparation of intravenous human and animal gamma globulins and isolation of albumin
DE2835843A1 (de) * 1978-08-16 1980-02-28 Blutspendedienst Dt Rote Kreuz Verfahren zur herstellung einer fuer die intravenoese anwendung geeigneten gammaglobulinloesung
AT359641B (de) * 1978-09-19 1980-11-25 Immuno Ag Verfahren zur herstellung eines intravenoes ver- abreichbaren antikoerperhaeltigen immunglobulin- praeparates
JPS5643218A (en) * 1979-09-17 1981-04-21 Morishita Seiyaku Kk Preparation of gamma-globulin for intravenous injection
US4374763A (en) * 1979-09-17 1983-02-22 Morishita Pharmaceutical Co., Ltd. Method for producing gamma-globulin for use in intravenous administration and method for producing a pharmaceutical preparation thereof
JPS56113713A (en) * 1980-02-14 1981-09-07 Chemo Sero Therapeut Res Inst Preparation of immunoglobulin with high content of monomer
US4396608A (en) * 1981-08-24 1983-08-02 Cutter Laboratories Intravenously injectable immune serum globulin
DE3271181D1 (en) * 1982-02-08 1986-06-19 Schweiz Serum & Impfinst Intravenously administrable human immunoglobuline and process for its preparation
US4439421A (en) * 1982-08-30 1984-03-27 Baxter Travenol Laboratories, Inc. Stabilized gamma globulin concentrate

Also Published As

Publication number Publication date
EP0116571A4 (en) 1986-03-18
IT1169788B (it) 1987-06-03
DE3382394D1 (de) 1991-10-02
EP0116571B2 (en) 1997-10-29
CA1239584A (en) 1988-07-26
IT8322665A0 (it) 1983-08-29
EP0116571B1 (en) 1991-08-28
JPS59501546A (ja) 1984-08-30
ES524890A0 (es) 1986-02-01
JPH08787B2 (ja) 1996-01-10
ATE66616T1 (de) 1991-09-15
EP0116571A1 (en) 1984-08-29
WO1984000891A1 (en) 1984-03-15

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