ES8604305A1 - Un metodo de hidrolizar celulosa - Google Patents

Un metodo de hidrolizar celulosa

Info

Publication number
ES8604305A1
ES8604305A1 ES543767A ES543767A ES8604305A1 ES 8604305 A1 ES8604305 A1 ES 8604305A1 ES 543767 A ES543767 A ES 543767A ES 543767 A ES543767 A ES 543767A ES 8604305 A1 ES8604305 A1 ES 8604305A1
Authority
ES
Spain
Prior art keywords
recombinant fungal
fungal cellobiohydrolases
cellobiohydrolases
glycosylated
ligated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES543767A
Other languages
English (en)
Other versions
ES543767A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of ES8604305A1 publication Critical patent/ES8604305A1/es
Publication of ES543767A0 publication Critical patent/ES543767A0/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2434Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2437Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • C12N15/625DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2434Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2445Beta-glucosidase (3.2.1.21)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01004Cellulase (3.2.1.4), i.e. endo-1,4-beta-glucanase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01021Beta-glucosidase (3.2.1.21)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01091Cellulose 1,4-beta-cellobiosidase (3.2.1.91)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/90Fusion polypeptide containing a motif for post-translational modification
    • C07K2319/91Fusion polypeptide containing a motif for post-translational modification containing a motif for glycosylation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

METODO PARA LA HIDROLISIS DE CELULOSA. CONSISTE EN LA TRANSFORMACION DE UNA CELULA HOSPEDADORA RECOMBINANTE, CON UN VECTOR EFICAZ EN EXPRESAR UNA SECUENCIA DE ADN QUE CODIFICA CELULOSA FUNGICA EN UNA CELDA HOSPEDANTE RECOMBINANTE, VECTOR QUE COMPRENDE DICHA SECUENCIA DE ADN EN UNION OPERABLE CON SECUENCIAS DE CONTROL COMPATIBLES CON LA CELULA HOSPEDASDORA CITADA; CRECIMIENTO DEL HOSPEDADOR EN UN MEDIO DE CULTIVO ADECUADO; Y TRATAMIENTO DE CELULOSA CON LA CELULASA PRODUCIDA POR LAS CELULAS HOSPEDADORES TRANSFORMADAS. TIENE APLICACIONES PARA LA PRODUCCION DE GLUCOSA EMPLEADA COMO ALIMENTO O COMO INTERMEDIO PARA LA FABRICACION DE OTROS PRODUCTOS, A PARTIR DE SOLIDOS MUNICIPALES, PAPEL USADO Y SUBPRODUCTOS AGRICOLAS.
ES543767A 1983-08-31 1985-05-31 Un metodo de hidrolizar celulosa Expired ES8604305A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52821683A 1983-08-31 1983-08-31
US63097484A 1984-07-16 1984-07-16

Publications (2)

Publication Number Publication Date
ES8604305A1 true ES8604305A1 (es) 1986-01-16
ES543767A0 ES543767A0 (es) 1986-01-16

Family

ID=27062651

Family Applications (3)

Application Number Title Priority Date Filing Date
ES535511A Expired ES8602139A1 (es) 1983-08-31 1984-08-30 Un metodo para producir una proteina heterologa madura.
ES543766A Expired ES8604304A1 (es) 1983-08-31 1985-05-31 Un metodo de hidrolizar celulosa
ES543767A Expired ES8604305A1 (es) 1983-08-31 1985-05-31 Un metodo de hidrolizar celulosa

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES535511A Expired ES8602139A1 (es) 1983-08-31 1984-08-30 Un metodo para producir una proteina heterologa madura.
ES543766A Expired ES8604304A1 (es) 1983-08-31 1985-05-31 Un metodo de hidrolizar celulosa

Country Status (8)

Country Link
EP (1) EP0137280B1 (es)
JP (2) JPH0616709B2 (es)
AU (1) AU589112B2 (es)
BR (1) BR8404346A (es)
CA (1) CA1338400C (es)
DE (2) DE3485558D1 (es)
DK (1) DK419584A (es)
ES (3) ES8602139A1 (es)

Families Citing this family (107)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI841500A0 (fi) * 1984-04-13 1984-04-13 Valtion Teknillinen Foerfarande foer uppbygnande av cellulolytiska jaeststammar.
US5320960A (en) * 1992-04-03 1994-06-14 Genencor International, Inc. Method of preparing solution enriched in xylanase using low molecular weight alcohol, organic salt and inorganic salt
US5298405A (en) * 1986-04-30 1994-03-29 Alko Limited Enzyme preparations with recombinantly-altered cellulose profiles and methods for their production
US5989870A (en) * 1986-04-30 1999-11-23 Rohm Enzyme Finland Oy Method for cloning active promoters
GB8610600D0 (en) * 1986-04-30 1986-06-04 Novo Industri As Transformation of trichoderma
GB8621626D0 (en) * 1986-09-08 1986-10-15 Health Lab Service Board Phenylalanine ammonia lyase
JP2507345B2 (ja) * 1986-09-16 1996-06-12 三井東圧化学株式会社 L―フェニルアラニン―アンモニアリ・ア―ゼ構造遺伝子
US5610034A (en) * 1987-04-29 1997-03-11 Alko Group Ltd. Immunoglobulin production by trichoderma
US5688290A (en) * 1989-10-19 1997-11-18 Genencor International, Inc. Degradation resistant detergent compositions based on cellulase enzymes
CA2069962A1 (en) * 1990-08-17 1992-02-18 Shi-Hsiang Shen Recombinant dna production of beta-1, 3-glucanase
US5650322A (en) * 1990-10-05 1997-07-22 Genencor International, Inc. Methods for stonewashing fabrics using endoglucanases
US5290474A (en) * 1990-10-05 1994-03-01 Genencor International, Inc. Detergent composition for treating cotton-containing fabrics containing a surfactant and a cellulase composition containing endolucanase III from trichoderma ssp
WO1992006221A1 (en) * 1990-10-05 1992-04-16 Genencor International, Inc. Methods for treating cotton-containing fabrics with cellulase
US5328841A (en) * 1990-10-05 1994-07-12 Genencor International, Inc. Methods for isolating EG III cellulase component and EG III cellulase in polyethylene glycol using inorganic salt and polyethylene glycol
CA2093422C (en) * 1990-10-05 2001-04-03 DETERGENT COMPOSITIONS CONTAINING LOW CBH I CONTENT CELLULASE COMPOSITIONS
US5997913A (en) * 1990-12-10 1999-12-07 Genencor International, Inc. Method enhancing flavor and aroma in foods by overexpression of β-glucosidase
US5443750A (en) * 1991-01-16 1995-08-22 The Procter & Gamble Company Detergent compositions with high activity cellulase and softening clays
JPH07506404A (ja) * 1992-05-01 1995-07-13 ジェネンコア インターナショナル インコーポレーテッド 綿含有織物をcbh iが多いセルラーゼで処理する方法
WO1994004673A1 (en) * 1992-08-19 1994-03-03 Alko Group Ltd. Fungal promoters active in the presence of glucose
JPH07508890A (ja) * 1993-05-10 1995-10-05 ギスト ブロカデス ナムローゼ フェンノートシャップ エンドグルカナーゼとセロビオヒドロラーゼの共同作用
US7005128B1 (en) 1993-12-17 2006-02-28 Genencor International, Inc. Enzyme feed additive and animal feed including it
US5861271A (en) * 1993-12-17 1999-01-19 Fowler; Timothy Cellulase enzymes and systems for their expressions
US6268196B1 (en) 1993-12-17 2001-07-31 Genencor International, Inc. Method and compositions for treating cellulose containing fabrics using truncated cellulase enzyme compositions
GB9400623D0 (en) * 1994-01-14 1994-03-09 Univ Leeds Exploitation of the cellulase enzyme complex of neurospora
ES2251717T3 (es) * 1994-03-08 2006-05-01 Novozymes A/S Nuevas celulasas alcalinas.
US5912157A (en) * 1994-03-08 1999-06-15 Novo Nordisk A/S Alkaline cellulases
US7816129B2 (en) 1994-07-29 2010-10-19 Ab Enzymes Gmbh Production and secretion of proteins of bacterial origin in filamentous fungi
US6001595A (en) * 1996-11-29 1999-12-14 Rohm Enzyme GmbH Promoters and uses thereof
DE69827712T3 (de) 1997-07-31 2009-07-09 Dsm Ip Assets B.V. Zusammensetzung für Brotverbesserung
US6558937B1 (en) 1997-07-31 2003-05-06 Dsm N.V. Cellulose degrading enzymes of aspergillus
WO2000022092A2 (en) * 1998-10-13 2000-04-20 Genesis Research And Development Corporation Limited Materials and methods for the modification of plant cell wall polysaccharides
WO2001004284A1 (en) * 1999-07-13 2001-01-18 Midwest Research Institute Cellobiohydrolase reduced glycosylation variants: cbhin45a; cbhin270a; and cbhin384a
US7375197B2 (en) 2002-01-14 2008-05-20 Midwest Research Institute Cellobiohydrolase I gene and improved variants
US8637293B2 (en) 1999-07-13 2014-01-28 Alliance For Sustainable Energy, Llc Cellobiohydrolase I enzymes
US20040018573A1 (en) 2002-04-18 2004-01-29 Power Scott D Production of functional antibodies in filamentous fungi
WO2004035070A1 (en) 2002-09-10 2004-04-29 Genencor International, Inc. Induction of gene expression using a high concentration sugar mixture
WO2004072225A2 (en) 2003-02-12 2004-08-26 Ramot At Tel Aviv University Ltd. Transgenic fungi expressing bcl-2 and methods of using bcl-2 or portions thereof for improving biomass production, survival, longevity, stress resistance and pathogenicity of fungi
JP2007534294A (ja) 2003-03-21 2007-11-29 ジェネンコー・インターナショナル・インク Cbh1相同体及び変異体cbh1セルラーゼ
CA2771875A1 (en) 2003-04-01 2005-01-06 Danisco Us Inc. Variant hypocrea jecorina cbh1
CN103088001A (zh) 2003-08-25 2013-05-08 诺维信股份有限公司 糖苷水解酶的变体
KR20120099303A (ko) 2003-11-06 2012-09-07 다니스코 유에스 인크. 프로테아제 저해자 및 그 변이체의 사상균 내에서의 발현
WO2006110677A2 (en) 2005-04-12 2006-10-19 Genencor International, Inc. Gene inactivated mutants with altered protein production
US8198046B2 (en) 2006-07-11 2012-06-12 Danisco Us Inc. KEX2 cleavage regions of recombinant fusion proteins
US20080026376A1 (en) 2006-07-11 2008-01-31 Huaming Wang KEX2 cleavage regions of recombinant fusion proteins
DE102006062045A1 (de) 2006-12-29 2008-07-03 Ab Enzymes Gmbh Verbessertes Verfahren zur Gewinnung von Öl aus Pflanzensamen
US8143046B2 (en) 2007-02-07 2012-03-27 Danisco Us Inc., Genencor Division Variant Buttiauxella sp. phytases having altered properties
US8093016B2 (en) 2007-05-21 2012-01-10 Danisco Us Inc. Use of an aspartic protease (NS24) signal sequence for heterologous protein expression
DK2235190T3 (en) 2007-12-13 2018-07-23 Danisco Us Inc COMPOSITIONS AND PROCEDURES FOR PRODUCING ISOPRENE
EP3406722A1 (en) 2008-07-02 2018-11-28 Danisco US Inc. Methods for producing isoprene free of c5 hydrocarbons under decoupling conditions and/or safe operating ranges
SG169641A1 (en) 2008-09-15 2011-04-29 Danisco Us Inc Systems using cell culture for production of isoprene
US8476049B2 (en) 2008-09-15 2013-07-02 Danisco Us Inc. Conversion of prenyl derivatives to isoprene
MY169163A (en) 2008-09-15 2019-02-19 Danisco Us Inc Increased isoprene production using the archaeal lower mevalonate pathway
JP5793424B2 (ja) 2008-12-30 2015-10-14 ダニスコ・ユーエス・インク イソプレンと副生成物の産出方法
WO2010099500A2 (en) 2009-02-26 2010-09-02 Codexis, Inc. Beta-glucosidase variant enzymes and related polynucleotides
CA2754580C (en) 2009-03-17 2014-06-17 Codexis, Inc. Variant endoglucanases and related polynucleotides
WO2010148148A2 (en) 2009-06-16 2010-12-23 Codexis, Inc. β-GLUCOSIDASE VARIANTS
BRPI1012922A2 (pt) 2009-06-16 2016-10-11 Codexis Inc polipeptídeo de b-glicosidase variante, vetor de expressão, célula hospedeira, método de produção de polipeptídeo de b-glicosidase variante, composição enzimática, método de conversão de um substrato de biomassa em açucar fermentável e método de produção de álcool
TWI434921B (zh) 2009-06-17 2014-04-21 Danisco Us Inc 從生物異戊二烯組合物製造燃料成分之方法及系統
EP2449124B1 (en) 2009-06-30 2015-05-27 Codexis, Inc. Production of fatty alcohols with fatty alcohol forming acyl-coa reductases (far)
CA2772859C (en) 2009-09-04 2015-05-26 Codexis, Inc. Variant cbh2 cellulases and related polynucleotides
WO2011041594A1 (en) 2009-09-30 2011-04-07 Codexis, Inc. Recombinant c1 b-glucosidase for production of sugars from cellulosic biomass
CN102666848B (zh) 2009-11-25 2014-09-24 科德克希思公司 用于从纤维素生物质产生可发酵的糖的重组嗜热子囊菌β-葡糖苷酶变体
MX355841B (es) 2009-11-25 2018-05-02 Codexis Inc Variantes de beta-glucosidasa recombinante para producción de azúcares solubles de biomasa celulósica.
CA2798937A1 (en) 2010-05-28 2011-12-01 Codexis, Inc. Pentose fermentation by a recombinant microorganism
CN103025688A (zh) 2010-06-17 2013-04-03 丹尼斯科美国公司 包含异戊二烯衍生物的燃料组合物
US8574878B2 (en) 2010-06-28 2013-11-05 Behnaz Behrouzian Fatty alcohol forming acyl reductases (FARs) and methods of use thereof
CA2807702C (en) 2010-08-20 2018-07-24 Codexis, Inc. Use of glycoside hydrolase 61 family proteins in processing of cellulose
WO2012027226A1 (en) 2010-08-24 2012-03-01 Danisco Us Inc. A food product comprising a low temperature rice protein concentrate
US8663962B2 (en) 2011-03-30 2014-03-04 Codexis, Inc. Pentose fermentation by a recombinant microorganism
US8778652B2 (en) 2011-06-30 2014-07-15 Codexis, Inc. Pentose fermentation by a recombinant microorganism
BR112014004171A2 (pt) 2011-08-22 2018-11-06 Codexis Inc variantes da proteína glicósideo hidrolase gh61 e cofatores que aumentam a atividade de gh61
BR112014015030A2 (pt) 2011-12-20 2017-06-13 Codexis Inc variantes da endoflucanase 1b (eg1b)
BR112014031024A2 (pt) 2012-06-11 2017-06-27 Codexis Inc xilanases e xilosidases fúngicas.
CA2891482A1 (en) 2012-11-20 2014-05-30 Codexis, Inc. Pentose fermentation by a recombinant microorganism
EP2931887A1 (en) 2012-12-12 2015-10-21 Danisco US Inc. Variants of cellobiohydrolases
CA2893059A1 (en) 2012-12-12 2014-06-19 Danisco Us Inc. Variants of cellobiohydrolases
MX2015007225A (es) 2012-12-12 2015-10-29 Danisco Us Inc Variantes de celobiohidrolasas.
US20160122735A1 (en) 2012-12-12 2016-05-05 Danisco Us Inc. Variants of cellobiohydrolases
CN104870638A (zh) 2012-12-12 2015-08-26 丹尼斯科美国公司 纤维二糖水解酶的变体
US8993275B2 (en) * 2013-02-12 2015-03-31 Novozymes, Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
US8778640B1 (en) * 2013-02-12 2014-07-15 Novozymes Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
US8771994B1 (en) * 2013-02-12 2014-07-08 Novozymes Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
US8778641B1 (en) * 2013-02-12 2014-07-15 Novozymes Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
BR112015023537B1 (pt) 2013-03-15 2022-11-29 Inpex Corporation Mutante de um microrganismo produtor de celulase,e, método para produção de uma celulase
WO2015011285A2 (en) * 2013-07-26 2015-01-29 Biomethodes Novel variant trichoderma reesei endoglucanases
AU2014296572A1 (en) 2013-07-29 2016-02-18 Danisco Us Inc. Variant enzymes
US10584323B2 (en) 2013-12-04 2020-03-10 Danisco Us Inc Glucoamylase variants
CN107429267B (zh) 2014-12-19 2021-07-16 丹尼斯科美国公司 葡糖淀粉酶共混物
KR102604503B1 (ko) 2015-05-07 2023-11-20 코덱시스, 인코포레이티드 페니실린-g 아실라아제
BR112017027729A2 (pt) 2015-07-07 2018-09-11 Danisco Us Inc indução de expressão de gene com o uso de uma mistura de açúcar de concentração alta
JP7128519B2 (ja) 2016-05-05 2022-08-31 コデクシス, インコーポレイテッド ペニシリンgアシラーゼ
WO2018093752A1 (en) 2016-11-15 2018-05-24 Danisco Us Inc. Filamentous fungi with improved protein production
MX2019007335A (es) 2016-12-21 2019-09-09 Dupont Nutrition Biosci Aps Métodos para usar serina proteasas termoestables.
EP3565893A4 (en) 2017-01-05 2020-12-09 Codexis, Inc. PENICILLIN G ACYLASES
WO2018169780A1 (en) 2017-03-15 2018-09-20 Dupont Nutrition Biosciences Aps Methods of using an archaeal serine protease
EP3583210B1 (en) 2017-03-15 2021-07-07 Danisco US Inc. Trypsin-like serine proteases and uses thereof
BR112019018969A2 (pt) 2017-03-15 2020-04-22 Dupont Nutrition Biosci Aps serina proteases similar à tripsina e usos das mesmas
CA3064574A1 (en) 2017-06-14 2018-12-20 Codexis, Inc. Engineered transaminase polypeptides for industrial biocatalysis
US11643642B2 (en) 2017-06-27 2023-05-09 Codexis, Inc. Penicillin-g acylases
US11319531B2 (en) 2017-11-07 2022-05-03 Codexis, Inc. Transglutaminase variants
BR112021000116A2 (pt) 2018-07-06 2021-04-06 Dupont Nutrition Biosciences Aps Aditivos de alimento contendo xilanase para alimento de animal à base de cereal
CA3103721A1 (en) 2018-07-09 2020-01-16 Codexis, Inc. Engineered deoxyribose-phosphate aldolases
MX2021005825A (es) 2018-11-20 2021-08-05 Dupont Nutrition Biosci Aps Polipéptidos del clado de fitasa con alta temperatura de desnaturalización (tm) robustos modificados por ingeniería genética y fragmentos de los mismos.
EP3935157A2 (en) 2019-03-08 2022-01-12 Danisco US Inc. Fusion polypeptides
EP3947442A2 (en) 2019-03-28 2022-02-09 Danisco US Inc. Engineered antibodies
US10917454B1 (en) 2019-08-01 2021-02-09 Rohde & Schwarz Gmbh & Co. Kg System and method for ATC voice quality assurance
EP4133064A2 (en) 2020-04-10 2023-02-15 Codexis, Inc. Engineered transaminase polypeptides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4275163A (en) * 1978-11-20 1981-06-23 The United States Of America As Represented By The Secretary Of The Army Cellulase-producing microorganism

Also Published As

Publication number Publication date
AU589112B2 (en) 1989-10-05
JPH0751071A (ja) 1995-02-28
DK419584D0 (da) 1984-08-31
ES8604304A1 (es) 1986-01-16
ES543767A0 (es) 1986-01-16
DK419584A (da) 1985-03-01
DE137280T1 (de) 1986-01-16
JP2584186B2 (ja) 1997-02-19
DE3485558D1 (de) 1992-04-16
JPS60149387A (ja) 1985-08-06
JPH0616709B2 (ja) 1994-03-09
BR8404346A (pt) 1985-07-30
EP0137280A1 (en) 1985-04-17
EP0137280B1 (en) 1992-03-11
ES535511A0 (es) 1985-11-16
CA1338400C (en) 1996-06-18
AU3253084A (en) 1985-03-07
ES543766A0 (es) 1986-01-16
ES8602139A1 (es) 1985-11-16

Similar Documents

Publication Publication Date Title
ES8604305A1 (es) Un metodo de hidrolizar celulosa
ZA914714B (en) A cell having a certain function in a process,containing recombinant dna encoding at least one enzyme,recombinant dna,enzyme for which the recombinant dna encodes and uses thereof
CA2206399A1 (en) Method for secreting thrombopoietin polypeptides
DE3587168D1 (de) Glucoamylasegen.
ATE355376T1 (de) Thermophiles expressionssystem in pilzen
NZ594810A (en) Cellulases, nucleic acids encoding them and methods for making and using them
DE3377363D1 (en) Gene coding for interleukin-2 polypeptide, recombinant dna carrying said gene, cell lines possessing the recombinant dna,and method for producing interleukin-2 using said cells
IE872455L (en) Improved recombinant expression
EP0402300A3 (en) Production of bacteria and yeast of hemoglobin and analogues thereof
CA2093428A1 (en) Methods for Treating Cotton-Containing Fabrics with Cellulase
IE862178L (en) Poly-kringle plasminogen activator
EP0338266A3 (en) Artificial chromosome vector
HU904957D0 (en) Parenchymal liver call growth factor, the gene coding this and process for producing transformants creating this factor
ATE386101T1 (de) Expressionsplasmide, durch einen osmb promoter reguliert
NZ211357A (en) Recombinant dna and antigenic protein coded for
PT97383A (pt) Processo para a producao de uma cadeia de globina, de um seu fragmento de ligacao e de hemoglobina, e de composicoes de hemoglobina
EP0123928A3 (en) Recombinant dna coding for a polypeptide displaying milk clotting activity
IL86058A0 (en) Production of proteins
ZA876840B (en) Lignin modifying and degrading enzymes
ES8706825A1 (es) Un procedimiento para preparar un plasmido recombinante
EP0165759A3 (en) Mammalian promotors useful in yeast expression
WO2000052133A3 (en) Hansenula polymorpha mutants and process for the preparation of recombinant proteins using the same
WO1999060152A8 (en) Process for sialylating glycoproteins
JPS6480295A (en) Beta-isopropylmalate dehydrogenase gene promoter and use thereof
KR940007182A (ko) 재조합 인간 알파 인터페론 발현벡터, 균주 및 이를 이용한 인간 알파 인터페론의 제조방법

Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960401