ES8604238A1 - Un procedimiento para la obtencion de imidazotiadiazolal- quen-carboxiamidas - Google Patents
Un procedimiento para la obtencion de imidazotiadiazolal- quen-carboxiamidasInfo
- Publication number
- ES8604238A1 ES8604238A1 ES544216A ES544216A ES8604238A1 ES 8604238 A1 ES8604238 A1 ES 8604238A1 ES 544216 A ES544216 A ES 544216A ES 544216 A ES544216 A ES 544216A ES 8604238 A1 ES8604238 A1 ES 8604238A1
- Authority
- ES
- Spain
- Prior art keywords
- opt
- alkyl
- substd
- aryl
- ring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE IMIDAZOTIADIAZOLAL-QUENCARBOXIAMIDAS, DE SUS FORMAS ESTEREOISOMERAS DE LOS DIFERENTES ENANTIOMEROS, DIASTEREOMEROS E ISOMEROS E/Z Y DE SUS SALES DE ADICION DE ACIDO FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE A Y R1-R7 PUEDEN SER VARIOS TIPOS DE RADICALES. COMPRENDE LA REACCION DE AMIDACION DE UN ACIDO ALQUENCARBOXILICO, DE FORMULA (II), CON UNA AMINA, DE FORMULA HNR6R7, EN LAS QUE TODOS LOS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), EN CASO DADO TRAS ACTIVACION DEL GRUPO CARBOXILO MEDIANTE EL CORRESPONDIENTE CLORURO DE ACILO. LA REACCION SE EFECTUA EN UN DISOLVENTE ORGANICO INERTE, A UNA TEMPERATURA COMPRENDIDA ENTRE 20JC Y 150JC. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO ANTIHIPERTENSIVOS, DIURETICOS Y URICOSURICOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3329621A DE3329621A1 (de) | 1983-08-17 | 1983-08-17 | Aminoalkyl-imidazothiadiazol-alkencarbonsaeureamide, neue zwischenprodukte zu ihrer herstellung, ihre herstellung und ihre verwendung in arzneimitteln |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8604238A1 true ES8604238A1 (es) | 1986-01-16 |
| ES544216A0 ES544216A0 (es) | 1986-01-16 |
Family
ID=6206712
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES535054A Granted ES535054A0 (es) | 1983-08-17 | 1984-08-10 | Imidazotiadiazolalquencarboxiamidas |
| ES544216A Expired ES8604238A1 (es) | 1983-08-17 | 1985-06-14 | Un procedimiento para la obtencion de imidazotiadiazolal- quen-carboxiamidas |
| ES544215A Expired ES8604237A1 (es) | 1983-08-17 | 1985-06-14 | Un procedimiento para la obtencion de imidazotiadiazolal- quen-carboxiamidas |
| ES544217A Expired ES8604239A1 (es) | 1983-08-17 | 1985-06-14 | Un procedimiento para la obtencion de imidazotiadiazolal- quen-carboxiamidas |
| ES544218A Expired ES8604240A1 (es) | 1983-08-17 | 1985-06-14 | Un procedimiento para la obtencion de carbonil compuestos |
| ES544220A Expired ES8604242A1 (es) | 1983-08-17 | 1985-06-14 | Un procedimiento para la obtencion de acidos alquencarboxi- licos |
| ES544219A Expired ES8604241A1 (es) | 1983-08-17 | 1985-06-14 | Un procedimiento para la obtencion de acidos alquencarboxi- licos |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES535054A Granted ES535054A0 (es) | 1983-08-17 | 1984-08-10 | Imidazotiadiazolalquencarboxiamidas |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES544215A Expired ES8604237A1 (es) | 1983-08-17 | 1985-06-14 | Un procedimiento para la obtencion de imidazotiadiazolal- quen-carboxiamidas |
| ES544217A Expired ES8604239A1 (es) | 1983-08-17 | 1985-06-14 | Un procedimiento para la obtencion de imidazotiadiazolal- quen-carboxiamidas |
| ES544218A Expired ES8604240A1 (es) | 1983-08-17 | 1985-06-14 | Un procedimiento para la obtencion de carbonil compuestos |
| ES544220A Expired ES8604242A1 (es) | 1983-08-17 | 1985-06-14 | Un procedimiento para la obtencion de acidos alquencarboxi- licos |
| ES544219A Expired ES8604241A1 (es) | 1983-08-17 | 1985-06-14 | Un procedimiento para la obtencion de acidos alquencarboxi- licos |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4588723A (es) |
| EP (1) | EP0141072A3 (es) |
| JP (1) | JPS6058989A (es) |
| KR (1) | KR850001762A (es) |
| AU (1) | AU3111184A (es) |
| CA (1) | CA1234113A (es) |
| DE (1) | DE3329621A1 (es) |
| DK (1) | DK394384A (es) |
| ES (7) | ES535054A0 (es) |
| FI (1) | FI843226A (es) |
| GR (1) | GR80133B (es) |
| HU (1) | HU190969B (es) |
| IL (1) | IL72678A0 (es) |
| NO (1) | NO843108L (es) |
| PT (1) | PT79084B (es) |
| ZA (1) | ZA846378B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0232612B1 (en) * | 1985-12-23 | 1990-04-04 | Dr. Lo. Zambeletti S.p.A. | Azacyclic compounds, processes for their preparation, and their use as pharmaceuticals |
| DE102005010215A1 (de) * | 2005-03-05 | 2006-09-07 | Bayer Cropscience Ag | Heterobicyclische Acrylamide |
| EP2682395A1 (en) * | 2012-07-04 | 2014-01-08 | Laboratorios Del. Dr. Esteve, S.A. | Imidazo[2,1-b]thiazole derivatives, their preparation and use as medicaments |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO811630L (no) * | 1980-05-29 | 1981-11-30 | Bayer Ag | Imidazoazolalkensyreamider, nye mellomprodukter for deres fremstilling, deres fremstilling og deres anvendelse som legemiddel |
-
1983
- 1983-08-17 DE DE3329621A patent/DE3329621A1/de not_active Withdrawn
-
1984
- 1984-07-24 AU AU31111/84A patent/AU3111184A/en not_active Abandoned
- 1984-07-26 US US06/634,851 patent/US4588723A/en not_active Expired - Fee Related
- 1984-08-02 NO NO843108A patent/NO843108L/no unknown
- 1984-08-06 EP EP84109291A patent/EP0141072A3/de not_active Withdrawn
- 1984-08-10 ES ES535054A patent/ES535054A0/es active Granted
- 1984-08-14 IL IL72678A patent/IL72678A0/xx unknown
- 1984-08-14 PT PT79084A patent/PT79084B/pt unknown
- 1984-08-15 FI FI843226A patent/FI843226A/fi not_active Application Discontinuation
- 1984-08-15 CA CA000461031A patent/CA1234113A/en not_active Expired
- 1984-08-16 JP JP59170086A patent/JPS6058989A/ja active Pending
- 1984-08-16 HU HU843114A patent/HU190969B/hu unknown
- 1984-08-16 ZA ZA846378A patent/ZA846378B/xx unknown
- 1984-08-16 KR KR1019840004913A patent/KR850001762A/ko not_active Application Discontinuation
- 1984-08-16 DK DK394384A patent/DK394384A/da not_active Application Discontinuation
- 1984-08-17 GR GR80133A patent/GR80133B/el unknown
-
1985
- 1985-06-14 ES ES544216A patent/ES8604238A1/es not_active Expired
- 1985-06-14 ES ES544215A patent/ES8604237A1/es not_active Expired
- 1985-06-14 ES ES544217A patent/ES8604239A1/es not_active Expired
- 1985-06-14 ES ES544218A patent/ES8604240A1/es not_active Expired
- 1985-06-14 ES ES544220A patent/ES8604242A1/es not_active Expired
- 1985-06-14 ES ES544219A patent/ES8604241A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES544215A0 (es) | 1986-01-16 |
| ES8600768A1 (es) | 1985-10-16 |
| ES544217A0 (es) | 1986-01-16 |
| US4588723A (en) | 1986-05-13 |
| EP0141072A3 (de) | 1986-01-08 |
| EP0141072A2 (de) | 1985-05-15 |
| ES8604237A1 (es) | 1986-01-16 |
| ES544219A0 (es) | 1986-01-16 |
| HU190969B (en) | 1986-12-28 |
| ES535054A0 (es) | 1985-10-16 |
| HUT36130A (en) | 1985-08-28 |
| ES544220A0 (es) | 1986-01-16 |
| KR850001762A (ko) | 1985-04-01 |
| JPS6058989A (ja) | 1985-04-05 |
| IL72678A0 (en) | 1984-11-30 |
| FI843226A (fi) | 1985-02-18 |
| ES544218A0 (es) | 1986-01-16 |
| FI843226A0 (fi) | 1984-08-15 |
| CA1234113A (en) | 1988-03-15 |
| ES8604239A1 (es) | 1986-01-16 |
| AU3111184A (en) | 1985-02-21 |
| DK394384A (da) | 1985-02-18 |
| GR80133B (en) | 1984-12-19 |
| ZA846378B (en) | 1985-05-29 |
| ES544216A0 (es) | 1986-01-16 |
| PT79084B (en) | 1986-08-14 |
| DE3329621A1 (de) | 1985-02-28 |
| ES8604240A1 (es) | 1986-01-16 |
| ES8604242A1 (es) | 1986-01-16 |
| NO843108L (no) | 1985-02-18 |
| DK394384D0 (da) | 1984-08-16 |
| ES8604241A1 (es) | 1986-01-16 |
| PT79084A (en) | 1984-09-01 |
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