ES8604101A1 - Procedimiento de preparacion de nuevos derivados a-etilben- zol con un grupo aminopropanolico sustituido y sus sales de adicion acidas y amonicas cuaternarias - Google Patents
Procedimiento de preparacion de nuevos derivados a-etilben- zol con un grupo aminopropanolico sustituido y sus sales de adicion acidas y amonicas cuaternariasInfo
- Publication number
- ES8604101A1 ES8604101A1 ES543801A ES543801A ES8604101A1 ES 8604101 A1 ES8604101 A1 ES 8604101A1 ES 543801 A ES543801 A ES 543801A ES 543801 A ES543801 A ES 543801A ES 8604101 A1 ES8604101 A1 ES 8604101A1
- Authority
- ES
- Spain
- Prior art keywords
- phenyl
- salts
- ols
- propan
- propoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Steroid Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS A-ETILBENZOL CON UN GRUPO AMINOPROPANOLICO SUSTITUIDO Y SUS SALES DE ADICION DE ACIDOS Y AMONICAS CUATERNARIAS, DE FORMULA (I), EN LA QUE R2 REPRESENTA ALQUILO C1-3; R3 ES CICLOALQUILO C3-6; Y R1 Y R4 PUEDEN SER VARIOS TIPOS DE RADICALES. COMPRENDE LA REACCION DE UN COMPUESTO DE FORMULA (I), PREFERENTEMENTE EN FORMA DE FENOLATO METALICO ALCALINO O AMONICO CUATERNARIO, CON UNA AMINA TERCIARIA DE FORMULA R2R3NCH2CH2CH2X, O UNA DE SUS SALES, EN LAS QUE X ES ALQUILSULFONILOXILO, ARILSULFONILOXILO O HALOGENO Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), EN PRESENCIA DE UN AGENTE AGLUTINANTE DE ACIDOS. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE LA INTOXICACION ETANOLICA AGUDA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU824190A HU189209B (en) | 1982-12-28 | 1982-12-28 | Process for production of new 1-/amino-alkoxi-phenil/-1-phenil propanols, of their acide additioned and quaternary salts and medical preparatives consisting of such compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8604101A1 true ES8604101A1 (es) | 1986-01-16 |
| ES543801A0 ES543801A0 (es) | 1986-01-16 |
Family
ID=10967268
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES528460A Expired ES8600204A1 (es) | 1982-12-28 | 1983-12-27 | Procedimiento de preparacion de nuevos deridados de alfa-etibenzol con un grupo amino propanolico sustituido y sus sales de adicion acidas y amonicas cuaternarias. |
| ES543801A Expired ES8604101A1 (es) | 1982-12-28 | 1985-06-01 | Procedimiento de preparacion de nuevos derivados a-etilben- zol con un grupo aminopropanolico sustituido y sus sales de adicion acidas y amonicas cuaternarias |
| ES543800A Granted ES543800A0 (es) | 1982-12-28 | 1985-06-01 | Procedimiento de preparacion de nuevos derivados -etilben- zol con un grupo aminopropanolico sustituido y sus sales de adicion acidas y amonicas cuaternarias |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES528460A Expired ES8600204A1 (es) | 1982-12-28 | 1983-12-27 | Procedimiento de preparacion de nuevos deridados de alfa-etibenzol con un grupo amino propanolico sustituido y sus sales de adicion acidas y amonicas cuaternarias. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES543800A Granted ES543800A0 (es) | 1982-12-28 | 1985-06-01 | Procedimiento de preparacion de nuevos derivados -etilben- zol con un grupo aminopropanolico sustituido y sus sales de adicion acidas y amonicas cuaternarias |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4618611A (es) |
| EP (1) | EP0115079B1 (es) |
| JP (1) | JPS59134755A (es) |
| AT (1) | ATE25976T1 (es) |
| AU (1) | AU558033B2 (es) |
| CA (1) | CA1211443A (es) |
| DE (1) | DE3370326D1 (es) |
| DK (1) | DK163237C (es) |
| ES (3) | ES8600204A1 (es) |
| FI (1) | FI78913C (es) |
| GR (1) | GR78773B (es) |
| HU (1) | HU189209B (es) |
| IL (1) | IL70558A (es) |
| ZA (1) | ZA839616B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9303210D0 (en) * | 1993-02-17 | 1993-03-31 | Univ Manitoba | Cancer treatment |
| US7858825B2 (en) * | 2007-02-15 | 2010-12-28 | Colorado State University Research Foundation | Acid and base stable diphenylmethanol derivatives and methods of use |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3075014A (en) * | 1960-06-14 | 1963-01-22 | Richardson Merrell Inc | Basic substituted alkoxy diphenylalkanols, diphenylalkenes and diphenylalkanes |
| US3494961A (en) * | 1965-03-12 | 1970-02-10 | Hoffmann La Roche | 1,4-bis-(p-(dialkylaminoalkoxy)aryl)-1,4-bis-(aryl)-2-b-1,4-diols |
| US4094908A (en) * | 1973-08-15 | 1978-06-13 | Richter Gedeon Vegyeszeti Gyar Rt. | Alpha-substituted benzhydrol derivatives |
| HU168432B (es) * | 1973-08-15 | 1976-04-28 |
-
1982
- 1982-12-28 HU HU824190A patent/HU189209B/hu not_active IP Right Cessation
-
1983
- 1983-12-23 CA CA000444259A patent/CA1211443A/en not_active Expired
- 1983-12-23 AU AU22913/83A patent/AU558033B2/en not_active Ceased
- 1983-12-27 IL IL70558A patent/IL70558A/xx unknown
- 1983-12-27 FI FI834798A patent/FI78913C/fi not_active IP Right Cessation
- 1983-12-27 ES ES528460A patent/ES8600204A1/es not_active Expired
- 1983-12-27 ZA ZA839616A patent/ZA839616B/xx unknown
- 1983-12-27 JP JP58244950A patent/JPS59134755A/ja active Granted
- 1983-12-27 US US06/565,901 patent/US4618611A/en not_active Expired - Fee Related
- 1983-12-27 DK DK601883A patent/DK163237C/da not_active IP Right Cessation
- 1983-12-28 DE DE8383113172T patent/DE3370326D1/de not_active Expired
- 1983-12-28 GR GR73371A patent/GR78773B/el unknown
- 1983-12-28 EP EP83113172A patent/EP0115079B1/de not_active Expired
- 1983-12-28 AT AT83113172T patent/ATE25976T1/de not_active IP Right Cessation
-
1985
- 1985-06-01 ES ES543801A patent/ES8604101A1/es not_active Expired
- 1985-06-01 ES ES543800A patent/ES543800A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ATE25976T1 (de) | 1987-04-15 |
| JPS59134755A (ja) | 1984-08-02 |
| HU189209B (en) | 1986-06-30 |
| EP0115079B1 (de) | 1987-03-18 |
| DE3370326D1 (en) | 1987-04-23 |
| CA1211443A (en) | 1986-09-16 |
| FI834798A (fi) | 1984-06-29 |
| FI78913C (fi) | 1989-10-10 |
| DK601883D0 (da) | 1983-12-27 |
| FI78913B (fi) | 1989-06-30 |
| ES8603811A1 (es) | 1986-01-01 |
| HUT36081A (en) | 1985-08-28 |
| DK601883A (da) | 1984-06-29 |
| ES528460A0 (es) | 1985-10-01 |
| EP0115079A1 (de) | 1984-08-08 |
| FI834798A0 (fi) | 1983-12-27 |
| AU558033B2 (en) | 1987-01-15 |
| AU2291383A (en) | 1984-07-05 |
| ZA839616B (en) | 1984-08-29 |
| ES543800A0 (es) | 1986-01-01 |
| US4618611A (en) | 1986-10-21 |
| ES8600204A1 (es) | 1985-10-01 |
| DK163237B (da) | 1992-02-10 |
| JPH0159264B2 (es) | 1989-12-15 |
| ES543801A0 (es) | 1986-01-16 |
| DK163237C (da) | 1992-06-29 |
| IL70558A (en) | 1987-03-31 |
| GR78773B (es) | 1984-10-02 |
| IL70558A0 (en) | 1984-03-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970401 |