ES8603270A1 - Procedimiento para preparar liposomas que contiene alergenoso fracciones de alergenos inhalables - Google Patents

Procedimiento para preparar liposomas que contiene alergenoso fracciones de alergenos inhalables

Info

Publication number
ES8603270A1
ES8603270A1 ES541944A ES541944A ES8603270A1 ES 8603270 A1 ES8603270 A1 ES 8603270A1 ES 541944 A ES541944 A ES 541944A ES 541944 A ES541944 A ES 541944A ES 8603270 A1 ES8603270 A1 ES 8603270A1
Authority
ES
Spain
Prior art keywords
liposomes
allergens
aliphatic acyl
allergies
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES541944A
Other languages
English (en)
Other versions
ES541944A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Basotherm GmbH
Original Assignee
Basotherm GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6232737&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8603270(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Basotherm GmbH filed Critical Basotherm GmbH
Publication of ES8603270A1 publication Critical patent/ES8603270A1/es
Publication of ES541944A0 publication Critical patent/ES541944A0/es
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/35Allergens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR LIPOSOMAS QUE CONTIENEN ALERGENOS O FRACCIONES DE ALERGENOS INHALABLES. COMPRENDE: A) MEZCLAR ENTRE SI DIACILGLICEROLFOSFATIDILETANOLAMINAS CON 8 A 24 ATOMOS DE CARBONO EN EL GRUPO ACILO ALIFATICO Y/U OTRAS LECITINAS O DERIVADOS DE LECITINAS DE FORMULA GENERAL (I), CON COLESTEROL Y ACIDOS FOSFATIDICOS, EN RELACION MOLAR DE 1 A 0,1 HASTA 0,4 EL COLESTEROL Y EL ACIDO EN CANTIDAD AJUSTADA A LA CARGA DEL ALERGENO QUE HA DE INCORPORARSE; B) DISOLVER LOS LIPIDOS EN UN DISOLVENTE COMO CLOROFORMO O METANOL Y EVAPORAR EL DISOLVENTE EN UN EVAPORADOR ROTATORIO; C) AÑADIR UN TAMPON DE FOSFATO ISOTONICO AL QUE PREVIAMENTE SE LE HABIA AGREGADO EL ALERGENO EN CONCENTRACION DE 0,1 A 1 MG/ML; Y D) MEDIANTE AGITACION O SONIFICACION SE PREPARAN LOS LISOSOMAS. SIENDO: R1 Y R2 RADICALES ACILO ALIFATICOS DE 8 A 24C, Y R2 TAMBIEN GRUPO ALQUILO. SE UTILIZAN EN PREPARADOS FARMACEUTICOS PARA EL TRATAMIENTO DE ALERGIAS.
ES541944A 1984-04-05 1985-04-03 Procedimiento para preparar liposomas que contiene alergenoso fracciones de alergenos inhalables Granted ES541944A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843412793 DE3412793A1 (de) 1984-04-05 1984-04-05 Liposomen mit inhalativen allergenen zur behandlung von allergien, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
ES8603270A1 true ES8603270A1 (es) 1985-12-16
ES541944A0 ES541944A0 (es) 1985-12-16

Family

ID=6232737

Family Applications (1)

Application Number Title Priority Date Filing Date
ES541944A Granted ES541944A0 (es) 1984-04-05 1985-04-03 Procedimiento para preparar liposomas que contiene alergenoso fracciones de alergenos inhalables

Country Status (8)

Country Link
EP (1) EP0158880B1 (es)
JP (1) JPH0776180B2 (es)
AT (1) ATE69949T1 (es)
DE (2) DE3412793A1 (es)
DK (1) DK139685A (es)
ES (1) ES541944A0 (es)
FI (1) FI851365L (es)
NO (1) NO851389L (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62270531A (ja) * 1985-11-01 1987-11-24 サントル ナシヨナ−ル ド ラ ルシエルシユ シヤンテイフイ−ク(セ−・エン・エル・エス) 生体内でのイメ−ジング及び治療用の新規エアロゾル組成物
KR900701304A (ko) * 1988-05-05 1990-12-01 루이즈 츄이 콜린스 에이미 사람 및/또는 동물용 알레르겐 탈감작제
FR2650181B1 (fr) * 1989-07-27 1993-12-03 Laboratoire Stallergenes Procede pour combiner un melange de substances heterogenes a des liposomes
US5290563A (en) * 1989-07-27 1994-03-01 Laboratoire Des Stallergenes Method for combining a mixture of heterogeneous substances with liposomes
NL9000207A (es) * 1990-01-29 1991-08-16 Duphar Int Res
DE10148065A1 (de) * 2001-09-28 2003-04-17 Max Planck Gesellschaft (Ester)-Lysolecithine in Liposomen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3185625A (en) * 1961-11-08 1965-05-25 Brown Ethan Allan Injectionable substances
US4199565A (en) * 1979-03-26 1980-04-22 Merck & Co., Inc. Liposome particle containing viral or bacterial antigenic subunit

Also Published As

Publication number Publication date
DE3412793A1 (de) 1985-10-17
EP0158880A3 (en) 1986-01-08
EP0158880B1 (de) 1991-12-04
ES541944A0 (es) 1985-12-16
JPH0776180B2 (ja) 1995-08-16
NO851389L (no) 1985-10-07
DK139685A (da) 1985-10-06
ATE69949T1 (de) 1991-12-15
JPS60224634A (ja) 1985-11-09
DE3584784D1 (de) 1992-01-16
FI851365A0 (fi) 1985-04-04
FI851365L (fi) 1985-10-06
EP0158880A2 (de) 1985-10-23
DK139685D0 (da) 1985-03-28

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20050927