ES8603270A1 - Procedimiento para preparar liposomas que contiene alergenoso fracciones de alergenos inhalables - Google Patents

Procedimiento para preparar liposomas que contiene alergenoso fracciones de alergenos inhalables

Info

Publication number
ES8603270A1
ES8603270A1 ES541944A ES541944A ES8603270A1 ES 8603270 A1 ES8603270 A1 ES 8603270A1 ES 541944 A ES541944 A ES 541944A ES 541944 A ES541944 A ES 541944A ES 8603270 A1 ES8603270 A1 ES 8603270A1
Authority
ES
Spain
Prior art keywords
liposomes
allergens
aliphatic acyl
allergies
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES541944A
Other languages
English (en)
Other versions
ES541944A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Basotherm GmbH
Original Assignee
Basotherm GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6232737&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8603270(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Basotherm GmbH filed Critical Basotherm GmbH
Publication of ES8603270A1 publication Critical patent/ES8603270A1/es
Publication of ES541944A0 publication Critical patent/ES541944A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR LIPOSOMAS QUE CONTIENEN ALERGENOS O FRACCIONES DE ALERGENOS INHALABLES. COMPRENDE: A) MEZCLAR ENTRE SI DIACILGLICEROLFOSFATIDILETANOLAMINAS CON 8 A 24 ATOMOS DE CARBONO EN EL GRUPO ACILO ALIFATICO Y/U OTRAS LECITINAS O DERIVADOS DE LECITINAS DE FORMULA GENERAL (I), CON COLESTEROL Y ACIDOS FOSFATIDICOS, EN RELACION MOLAR DE 1 A 0,1 HASTA 0,4 EL COLESTEROL Y EL ACIDO EN CANTIDAD AJUSTADA A LA CARGA DEL ALERGENO QUE HA DE INCORPORARSE; B) DISOLVER LOS LIPIDOS EN UN DISOLVENTE COMO CLOROFORMO O METANOL Y EVAPORAR EL DISOLVENTE EN UN EVAPORADOR ROTATORIO; C) AÑADIR UN TAMPON DE FOSFATO ISOTONICO AL QUE PREVIAMENTE SE LE HABIA AGREGADO EL ALERGENO EN CONCENTRACION DE 0,1 A 1 MG/ML; Y D) MEDIANTE AGITACION O SONIFICACION SE PREPARAN LOS LISOSOMAS. SIENDO: R1 Y R2 RADICALES ACILO ALIFATICOS DE 8 A 24C, Y R2 TAMBIEN GRUPO ALQUILO. SE UTILIZAN EN PREPARADOS FARMACEUTICOS PARA EL TRATAMIENTO DE ALERGIAS.
ES541944A 1984-04-05 1985-04-03 Procedimiento para preparar liposomas que contiene alergenoso fracciones de alergenos inhalables Granted ES541944A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843412793 DE3412793A1 (de) 1984-04-05 1984-04-05 Liposomen mit inhalativen allergenen zur behandlung von allergien, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
ES8603270A1 true ES8603270A1 (es) 1985-12-16
ES541944A0 ES541944A0 (es) 1985-12-16

Family

ID=6232737

Family Applications (1)

Application Number Title Priority Date Filing Date
ES541944A Granted ES541944A0 (es) 1984-04-05 1985-04-03 Procedimiento para preparar liposomas que contiene alergenoso fracciones de alergenos inhalables

Country Status (8)

Country Link
EP (1) EP0158880B1 (es)
JP (1) JPH0776180B2 (es)
AT (1) ATE69949T1 (es)
DE (2) DE3412793A1 (es)
DK (1) DK139685A (es)
ES (1) ES541944A0 (es)
FI (1) FI851365L (es)
NO (1) NO851389L (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62270531A (ja) * 1985-11-01 1987-11-24 サントル　ナシヨナ−ル　ド　ラ　ルシエルシユ　シヤンテイフイ−ク（セ−・エン・エル・エス） 生体内でのイメ−ジング及び治療用の新規エアロゾル組成物
KR900701304A (ko) * 1988-05-05 1990-12-01 루이즈 츄이 콜린스 에이미 사람 및/또는 동물용 알레르겐 탈감작제
FR2650181B1 (fr) * 1989-07-27 1993-12-03 Laboratoire Stallergenes Procede pour combiner un melange de substances heterogenes a des liposomes
US5290563A (en) * 1989-07-27 1994-03-01 Laboratoire Des Stallergenes Method for combining a mixture of heterogeneous substances with liposomes
NL9000207A (es) * 1990-01-29 1991-08-16 Duphar Int Res
DE10148065A1 (de) * 2001-09-28 2003-04-17 Max Planck Gesellschaft (Ester)-Lysolecithine in Liposomen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3185625A (en) * 1961-11-08 1965-05-25 Brown Ethan Allan Injectionable substances
US4199565A (en) * 1979-03-26 1980-04-22 Merck & Co., Inc. Liposome particle containing viral or bacterial antigenic subunit

Also Published As

Publication number Publication date
DK139685A (da) 1985-10-06
FI851365L (fi) 1985-10-06
DE3584784D1 (de) 1992-01-16
DK139685D0 (da) 1985-03-28
FI851365A0 (fi) 1985-04-04
EP0158880A2 (de) 1985-10-23
DE3412793A1 (de) 1985-10-17
EP0158880A3 (en) 1986-01-08
NO851389L (no) 1985-10-07
JPS60224634A (ja) 1985-11-09
ATE69949T1 (de) 1991-12-15
ES541944A0 (es) 1985-12-16
JPH0776180B2 (ja) 1995-08-16
EP0158880B1 (de) 1991-12-04

Similar Documents

Publication Publication Date Title
DE2818655A1 (de) Liposome
Kelly et al. Effects of arachidonic acid and other unsaturated fatty acids on mitogenesis in human lymphocytes
EP1511499B1 (en) Immunomodulatory compounds and methods of use thereof
Bangham A correlation between surface charge and coagulant action of phospholipids
Greiner et al. Phospholipids in meibomian gland secretion
Robinson et al. The similar effect of chylomicra and ethanolamine phosphatide on the generation of thrombin during coagulation
JPH08500816A (ja) スフィンゴシン−１−ホスフェートその誘導体および擬態物による細胞能動性の阻害方法、並びにスフィンゴシン−１−ホスフェートおよびその誘導体の合成方法
AU690520B2 (en) Prophylactic and remedy for viral diseases in respiratory tract
FR2417500A1 (fr) Derives d'amino-acides cycliques dehydrogenes et leur utilisation therapeutique
Geilen et al. The phospholipid analogue, hexadecylphosphocholine, inhibits protein kinase C in vitro and antagonises phorbol ester-stimulated cell proliferation
ES8603270A1 (es) Procedimiento para preparar liposomas que contiene alergenoso fracciones de alergenos inhalables
Strickland et al. The action of the phosphatases of human brain on lipid phosphate esters
KR950700083A (ko) 경구용 백신(oral vaccine)
DE3376976D1 (en) New d-mannite derivatives as starting products for the synthesis of phospholipids
IL81868A (en) Aqueous phospholipid solutions containing hydroxyalkylamines and their esters
LeBaron et al. Structure of brain tissue lipides
Silver et al. Evaluation of activity of phospholipids in blood coagulation in vitro
DK392786D0 (da) Farmaceutiske praeparater indeholdende acylerede phospholipider
ES8207186A1 (es) Procedimiento para la separacion de fosfolipidos acilados a partir de productos de fosfatidilcolina que los contienen .
DE3363059D1 (en) Process for winning phosphatide ethanolic fractions highly enriched with phosphatidyl choline
JPS55127318A (en) Emulsifier composition
GB1426479A (en) Dermatological composition and method
Streicher et al. Phosphate (P32) exchange in brain phospholipids in vivo and in vitro.
WO1992004907A1 (en) Natural pulmonary surfactants and lipid extracts thereof
LeBaron Metabolism of myelin constituents

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20050927