ES8602679A1 - Un procedimiento para preparar derivados de isoquinolinas. - Google Patents
Un procedimiento para preparar derivados de isoquinolinas.Info
- Publication number
- ES8602679A1 ES8602679A1 ES536944A ES536944A ES8602679A1 ES 8602679 A1 ES8602679 A1 ES 8602679A1 ES 536944 A ES536944 A ES 536944A ES 536944 A ES536944 A ES 536944A ES 8602679 A1 ES8602679 A1 ES 8602679A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- polymethylene
- alkoxy
- opt
- alkanoyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR DERIVADOS DE ISOQUINOLINA. CONSISTENTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (V) CON UN COMPUESTO DE FORMULA R1 R2 NCOQ1, DONDE Q1 ES UN GRUPO SALIENTE; POSTERIORMENTE TRANSFORMAR LOS GRUPOS SUSTITUYENTES Y/O FORMAR UNA SAL FARMACEUTICAMENTE ACEPTABLE. LA REACCION PUEDE TENER LUGAR EN PRESENCIA O EN AUSENCIA DE DISOLVENTE INERTE Y A UNA TEMPERATURA COMPRENDIDA ENTRE 150 Y 180C. SE OBTIENEN COMPUESTOS DE FORMULA (I) Y (II). DE APLICACION COMO ANTIINFLAMATORIOS, ANTIRREUMATICOS Y ANTIALERGICOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB838328052A GB8328052D0 (en) | 1983-10-20 | 1983-10-20 | Compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8602679A1 true ES8602679A1 (es) | 1985-11-16 |
ES536944A0 ES536944A0 (es) | 1985-11-16 |
Family
ID=10550488
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES536944A Granted ES536944A0 (es) | 1983-10-20 | 1984-10-19 | Un procedimiento para preparar derivados de isoquinolinas. |
ES541598A Granted ES541598A0 (es) | 1983-10-20 | 1985-03-26 | Un procedimiento para preparar derivados de isoquinolina. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES541598A Granted ES541598A0 (es) | 1983-10-20 | 1985-03-26 | Un procedimiento para preparar derivados de isoquinolina. |
Country Status (10)
Country | Link |
---|---|
US (1) | US4578393A (es) |
EP (1) | EP0139296A3 (es) |
JP (1) | JPS6097961A (es) |
AU (1) | AU573272B2 (es) |
CA (1) | CA1246069A (es) |
ES (2) | ES536944A0 (es) |
GB (1) | GB8328052D0 (es) |
GR (1) | GR80712B (es) |
NZ (1) | NZ209919A (es) |
ZA (1) | ZA848177B (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8426584D0 (en) * | 1984-10-19 | 1984-11-28 | Beecham Group Plc | Compounds |
GB8509834D0 (en) * | 1985-04-17 | 1985-05-22 | Beecham Group Plc | Compounds |
US5049564A (en) * | 1989-11-17 | 1991-09-17 | Abbott Laboratories | 5-HT selective agents |
US5244888A (en) * | 1989-11-17 | 1993-09-14 | Abbott Laboratories | 5-HT selective agents |
US5126351A (en) * | 1991-01-24 | 1992-06-30 | Glaxo Inc. | Antitumor compounds |
GB9322828D0 (en) * | 1993-11-05 | 1993-12-22 | Sandoz Ltd | Organic compounds |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1394702A (en) * | 1972-11-25 | 1975-05-21 | Aspro Nicholas Ltd | Pharmacologically active isoquinoline derivatives |
DE2309367A1 (de) * | 1973-02-24 | 1974-09-05 | Hoechst Ag | 1,4-dihydro-4-h-isochinolinderivate und verfahren zu ihrer herstellung |
DE2818403A1 (de) * | 1978-04-27 | 1979-11-08 | Hoechst Ag | Neue isochinolinderivate und verfahren zu ihrer herstellung |
US4436911A (en) * | 1981-05-12 | 1984-03-13 | William H. Rorer, Inc. | Heterocyclic amidinoureas |
-
1983
- 1983-10-20 GB GB838328052A patent/GB8328052D0/en active Pending
-
1984
- 1984-10-16 EP EP84112462A patent/EP0139296A3/en not_active Ceased
- 1984-10-18 NZ NZ209919A patent/NZ209919A/xx unknown
- 1984-10-18 CA CA000465774A patent/CA1246069A/en not_active Expired
- 1984-10-18 GR GR80712A patent/GR80712B/el unknown
- 1984-10-18 AU AU34459/84A patent/AU573272B2/en not_active Ceased
- 1984-10-19 JP JP59220319A patent/JPS6097961A/ja active Pending
- 1984-10-19 ZA ZA848177A patent/ZA848177B/xx unknown
- 1984-10-19 ES ES536944A patent/ES536944A0/es active Granted
- 1984-10-22 US US06/663,232 patent/US4578393A/en not_active Expired - Fee Related
-
1985
- 1985-03-26 ES ES541598A patent/ES541598A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
GB8328052D0 (en) | 1983-11-23 |
ZA848177B (en) | 1985-09-25 |
GR80712B (en) | 1985-02-20 |
ES8602677A1 (es) | 1985-12-01 |
CA1246069A (en) | 1988-12-06 |
US4578393A (en) | 1986-03-25 |
EP0139296A2 (en) | 1985-05-02 |
EP0139296A3 (en) | 1986-03-19 |
ES541598A0 (es) | 1985-12-01 |
AU3445984A (en) | 1985-04-26 |
JPS6097961A (ja) | 1985-05-31 |
NZ209919A (en) | 1988-06-30 |
AU573272B2 (en) | 1988-06-02 |
ES536944A0 (es) | 1985-11-16 |
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