HUT47283A - Process for producing new spiro-quinazolin-imidazolidine derivatives
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Process for producing new spiro-quinazolin-imidazolidine derivatives
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Publication number
HUT47283A
HUT47283AHU864457AHU445786AHUT47283AHU T47283 AHUT47283 AHU T47283AHU 864457 AHU864457 AHU 864457AHU 445786 AHU445786 AHU 445786AHU T47283 AHUT47283 AHU T47283A
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Application filed by Tanabe Seiyaku CofiledCriticalTanabe Seiyaku Co
Priority to HU864457ApriorityCriticalpatent/HU200182B/en
Publication of HUT47283ApublicationCriticalpatent/HUT47283A/en
Publication of HU200182BpublicationCriticalpatent/HU200182B/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Spiro(1,2,3,4-tetrahydroquinazoline -4,4'-imidazolidine) derivs. of formula (I) and their salts are new. In (I), R = H or 1-5C alkyl; R1 = 1-5C alkyl, opt. substd. Ph or aralkyl; R2-R5 = H, halogen, 1-5C alkyl, 1-5C alkoxy, (2-6C)alkoxycarbonyl or (2-6C)alkoxycarbonyl (2-6C)alkenyl; or 2 adjacent substituents R2-R5 = OCH2O; and the other 2 substituents = H. - Intermediates of formula (II) are new. X = CONH2 or C(=NH)SR6; R6 = 1-5C alkyl.
HU864457A1985-06-061986-10-23Process for producing new spiroquinazoline imidazolidine derivatives and pharmaceutical compositions comprising same
HU200182B
(en)