ES8601229A1 - Procedimiento para la obtencion de o-glicosilamidas sustituidas - Google Patents

Procedimiento para la obtencion de o-glicosilamidas sustituidas

Info

Publication number
ES8601229A1
ES8601229A1 ES538339A ES538339A ES8601229A1 ES 8601229 A1 ES8601229 A1 ES 8601229A1 ES 538339 A ES538339 A ES 538339A ES 538339 A ES538339 A ES 538339A ES 8601229 A1 ES8601229 A1 ES 8601229A1
Authority
ES
Spain
Prior art keywords
glycosylamides
acyl
substituted
preparation
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES538339A
Other languages
English (en)
Other versions
ES538339A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES8601229A1 publication Critical patent/ES8601229A1/es
Publication of ES538339A0 publication Critical patent/ES538339A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE 0-ACILGLICOSILAMIDAS SUSTITUIDAS DE FORMULA (I). CONSISTENTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO AMINO BIEN EN FORMA LIBRE O EN FORMA DE SAL DE ADICION DE ACIDO Y POSTERIORMENTE LA GLICOSILAMINA ASI OBTENIDA ES ACILADA EN EL ATOMO DE NITROGENO CON UN DERIVADO DE ACIDO CARBOXILICO ACIDO CARBONICO ACIDO TIOCARBONICO O ISOCIANATO. EL PRODUCTO INTERMEDIO SE HACE REACCIONAR CON UN DERIVADO DE ACIDO CARBOXILICO ACIDO CARBONICO ACIDO TIOCARBONICO O ISOCIANATO. LAS REACCIONES SE REALIZAN A TEMPERATURAS COMPRENDIDAS ENTRE C30 Y 80JC Y OPCIONALMENTE EN PRESENCIA DE AGENTES AUXILIARES BASICOS. DE APLICACION COMO ACTIVADORES DEL SISTEMA INMUNOLOGICO.
ES538339A 1983-12-07 1984-12-06 Procedimiento para la obtencion de o-glicosilamidas sustituidas Granted ES538339A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833344257 DE3344257A1 (de) 1983-12-07 1983-12-07 Substituierte o-acyl-glycosylamide, verfahren zu iherer herstellung sowie ihre verwendung

Publications (2)

Publication Number Publication Date
ES8601229A1 true ES8601229A1 (es) 1985-11-01
ES538339A0 ES538339A0 (es) 1985-11-01

Family

ID=6216279

Family Applications (1)

Application Number Title Priority Date Filing Date
ES538339A Granted ES538339A0 (es) 1983-12-07 1984-12-06 Procedimiento para la obtencion de o-glicosilamidas sustituidas

Country Status (12)

Country Link
US (1) US4574122A (es)
EP (1) EP0149760B1 (es)
JP (1) JPS60155188A (es)
KR (1) KR860002110B1 (es)
AT (1) ATE45746T1 (es)
CA (1) CA1234109A (es)
DE (2) DE3344257A1 (es)
DK (1) DK583184A (es)
ES (1) ES538339A0 (es)
GR (1) GR81181B (es)
IL (1) IL73721A (es)
ZA (1) ZA849504B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3403495A1 (de) * 1983-11-23 1985-05-30 Bayer Ag, 5090 Leverkusen Phosphorylierte glycosylamide, -harnstoffe, -carbamate und -thiocarbamate, verfahren zu ihrer herstellung sowie ihre verwendung
JPS60149597A (ja) * 1983-12-14 1985-08-07 バイエル・アクチエンゲゼルシヤフト Ｎ‐グリコシル化ウレア類、カルバメート類及びチオカルバメート類
DE3346623A1 (de) * 1983-12-14 1985-07-04 Bayer Ag, 5090 Leverkusen N-glycosylierte harnstoffe, carbamate und thiocarbamate, verfahren zu ihrer herstellung sowie ihre verwendung
DE3508025A1 (de) * 1985-03-07 1986-09-11 Bayer Ag, 5090 Leverkusen Substituierte o-sulfonyl-glycosylamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE3521994A1 (de) * 1985-06-20 1987-01-02 Bayer Ag N-(2-aminoacylamido-2-desoxy-hexosyl)-amide-, -carbamate und -harnstoffe, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
DE3604681A1 (de) * 1986-02-14 1987-08-20 Bayer Ag Neue n-glycosylamidderivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE3812681A1 (de) * 1988-04-16 1989-11-02 Bayer Ag Substituierte n-glycosylamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US5476924A (en) * 1989-01-27 1995-12-19 Duke University Protecting group for acetals and methods of using the same in the activation of saccharides
WO1990014844A2 (en) * 1989-06-06 1990-12-13 Neorx Corporation Sugars as cleavable linkers for the delivery and release of agents in native form
US5872111A (en) * 1997-05-19 1999-02-16 Lever Brothers Company, Division Of Conopco, Inc. Compositions comprising glycosylamide surfactants

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2612497A (en) * 1948-01-24 1952-09-30 Hendrik W Meijer Process for manufacture of hexose ureides and thioureides
US3843799A (en) * 1973-01-26 1974-10-22 Alberta Res Council Method of feeding ruminants n-glucosyl-n'-ydroxymethylurea
US4025622A (en) * 1974-03-06 1977-05-24 Haruo Ogura Novel sugar ureide and thioureide derivatives
US4066750A (en) * 1976-08-02 1978-01-03 Astra Chemical Products Ab Lactosyl substituted ureides in ruminant feedstuff
DE3213650A1 (de) * 1982-04-14 1983-10-27 Bayer Ag, 5090 Leverkusen N-glycosylierte carbonsaeureamid-derivate, verfahren zu ihrer herstellung sowie ihre verwendung zur beeinflussung der koerpereigenen abwehr

Also Published As

Publication number Publication date
EP0149760A3 (en) 1987-04-01
KR850004495A (ko) 1985-07-15
DK583184A (da) 1985-06-08
GR81181B (en) 1985-04-03
US4574122A (en) 1986-03-04
CA1234109A (en) 1988-03-15
EP0149760B1 (de) 1989-08-23
ATE45746T1 (de) 1989-09-15
IL73721A0 (en) 1985-03-31
DE3479502D1 (en) 1989-09-28
EP0149760A2 (de) 1985-07-31
IL73721A (en) 1990-04-29
DK583184D0 (da) 1984-12-06
ZA849504B (en) 1985-07-31
DE3344257A1 (de) 1985-06-13
KR860002110B1 (ko) 1986-11-26
JPS60155188A (ja) 1985-08-15
ES538339A0 (es) 1985-11-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303