DK0545983T3 - Mellemprodukter for chelateringsmidler med forud fastsat symmetri samt fremgangsmåde til fremstilling heraf - Google Patents

Mellemprodukter for chelateringsmidler med forud fastsat symmetri samt fremgangsmåde til fremstilling heraf

Info

Publication number
DK0545983T3
DK0545983T3 DK91914890.8T DK91914890T DK0545983T3 DK 0545983 T3 DK0545983 T3 DK 0545983T3 DK 91914890 T DK91914890 T DK 91914890T DK 0545983 T3 DK0545983 T3 DK 0545983T3
Authority
DK
Denmark
Prior art keywords
preparation
chelating agents
well
pct
intermediate products
Prior art date
Application number
DK91914890.8T
Other languages
English (en)
Inventor
Fulvio Uggeri
Pier Lucio Anelli
Marcella Murru
Mario Virtuani
Original Assignee
Dibra Spa
Bracco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dibra Spa, Bracco Spa filed Critical Dibra Spa
Application granted granted Critical
Publication of DK0545983T3 publication Critical patent/DK0545983T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
DK91914890.8T 1990-08-29 1991-08-14 Mellemprodukter for chelateringsmidler med forud fastsat symmetri samt fremgangsmåde til fremstilling heraf DK0545983T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02131890A IT1243801B (it) 1990-08-29 1990-08-29 Intermedi per agenti chelanti con simmetria prefissata, e procedimentoper la loro preparazione

Publications (1)

Publication Number Publication Date
DK0545983T3 true DK0545983T3 (da) 1994-11-28

Family

ID=11180039

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91914890.8T DK0545983T3 (da) 1990-08-29 1991-08-14 Mellemprodukter for chelateringsmidler med forud fastsat symmetri samt fremgangsmåde til fremstilling heraf

Country Status (13)

Country Link
US (1) US5424423A (da)
EP (1) EP0545983B1 (da)
JP (1) JP3119872B2 (da)
KR (1) KR930701419A (da)
AT (1) ATE113278T1 (da)
AU (1) AU650903B2 (da)
CA (1) CA2090433A1 (da)
DE (2) DE545983T1 (da)
DK (1) DK0545983T3 (da)
ES (1) ES2041617T3 (da)
GR (1) GR930300084T1 (da)
IT (1) IT1243801B (da)
WO (1) WO1992004336A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5539105A (en) * 1990-08-29 1996-07-23 Dibra S.P.A. Intermediates for chelating agents with prefixed symmetry and process for their preparation
US6875864B2 (en) 1991-08-01 2005-04-05 Bracco International B.V. Aminocarboxylate ligands having substituted aromatic amide moieties
US5410043A (en) * 1991-12-06 1995-04-25 Schering Aktiengesellschaft Process for the production of mono-N-substituted tetraaza macrocycles
DE4237943C2 (de) * 1992-11-06 1997-10-23 Schering Ag Verfahren zur Herstellung von Metallkomplexen der N-beta-Hydroxyalkyl-tri-N-carboxyalkyl-1,4,7,10-tetraazacyclododecan- und N-beta-Hydroxyalkyl-tri-N-carboxyalkyl-1,4,8,11-tetraazacyclotetradecan-Derivate
DE4218744C2 (de) * 1992-06-04 1997-11-06 Schering Ag Verfahren zur Herstellung von N-ß-Hxdroxyalkyl-tri-N-carboxylalkyl-1,4,7,10-tetraazacyclododecan- und N-ß-Hydroxyalkyl-tri-N-carboxyalkyl-1,4,8,11-tetraazacyclotetradecan-Derivaten und deren Metallkomplexe
EP0588229A3 (en) * 1992-09-12 1994-06-15 Hoechst Ag Macrocyclic chelating agents for the preparation of technetium or rhenium complexes
EP0702677A1 (en) * 1994-04-08 1996-03-27 BRACCO International B.V. Aromatic amide compounds and metal chelates thereof
US6693190B1 (en) 1994-05-11 2004-02-17 Bracco International B.V. Enhanced relaxivity monomeric and multimeric compounds
FR2725449B1 (fr) * 1994-10-05 1996-12-27 Air Liquide Derives de polyazacycloalcanes, leurs complexes metalliques et produits pharmaceutiques incorporant ces complexes
GB9504910D0 (en) * 1995-03-10 1995-04-26 Nycomed Imaging As Compounds
GB9504922D0 (en) * 1995-03-10 1995-04-26 Nycomed As Process
IT1292130B1 (it) * 1997-06-11 1999-01-25 Bracco Spa Processo per la preparazione dell'acido 1,4,7,10-tetraazaciclododecan -1,4,7-triacetico e suoi derivati

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3979379A (en) * 1975-04-25 1976-09-07 The United States Of America As Represented By The Secretary Of The Army Process for producing 1,3,5,7-tetraalkanoyl-1,3,5,7-octahydrotetrazocines
US4085106A (en) * 1976-01-07 1978-04-18 E. I. Du Pont De Nemours And Company Bicyclic and tricyclic trisaminomethanes
JPS53144593A (en) * 1977-05-19 1978-12-15 Iwao Tabuse Alklycyclum
JPS5672070A (en) * 1979-11-14 1981-06-16 Iwao Tabuse Preparation of uranyl ion trapping agent
US4885363A (en) * 1987-04-24 1989-12-05 E. R. Squibb & Sons, Inc. 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
US5247077A (en) * 1989-06-23 1993-09-21 Celltech Limited Tri-aza macrocycles and processes for their preparation

Also Published As

Publication number Publication date
ES2041617T3 (es) 1994-12-16
EP0545983A1 (en) 1993-06-16
IT9021318A0 (it) 1990-08-29
IT9021318A1 (it) 1992-02-29
ES2041617T1 (es) 1993-12-01
DE545983T1 (de) 1993-10-14
KR930701419A (ko) 1993-06-11
ATE113278T1 (de) 1994-11-15
AU650903B2 (en) 1994-07-07
DE69104842T2 (de) 1995-03-23
AU8412591A (en) 1992-03-30
WO1992004336A1 (en) 1992-03-19
IT1243801B (it) 1994-06-28
CA2090433A1 (en) 1992-03-01
JP3119872B2 (ja) 2000-12-25
JPH06503303A (ja) 1994-04-14
GR930300084T1 (en) 1993-09-30
EP0545983B1 (en) 1994-10-26
US5424423A (en) 1995-06-13
DE69104842D1 (de) 1994-12-01

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