ES8507476A1 - Un procedimiento para la preparacion de nuevos benzonitrilos - Google Patents
Un procedimiento para la preparacion de nuevos benzonitrilosInfo
- Publication number
- ES8507476A1 ES8507476A1 ES529879A ES529879A ES8507476A1 ES 8507476 A1 ES8507476 A1 ES 8507476A1 ES 529879 A ES529879 A ES 529879A ES 529879 A ES529879 A ES 529879A ES 8507476 A1 ES8507476 A1 ES 8507476A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- image
- enterotoxin
- amidine derivatives
- induced
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/195—Radicals derived from nitrogen analogues of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/21—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE BENZONITRILOS, DE FORMULA GENERAL (I), EN LA QUE R5 ES HIDROGENO, HIDROXI, ALCOXI, ARILOXI O HETEROARILOXI, Y SUS SALES DE ADICION DE ACIDO FARMACEUTICAMENTE ACEPTABLES.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL (II), EN LA QUE R5 TIENE EL SIGNIFICADO YA MENCIONADO; E Y ES HALOGENO, CON UN REACTIVO DE CIANURO APROPIADO Y, OPCIONALMENTE, SE PUEDE CONVERTIR EL COMPUESTO DE FORMULA (I) EN OTRO COMPUESTO DE FORMULA (I).DE APLICACION EN EL TRATAMIENTO DE DIARREAS INDUCIDAS POR ENTEROTOXINAS EN PERSONAS Y DE DIARREAS BLANCAS EN ANIMALES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8217452 | 1982-06-16 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES529879A0 ES529879A0 (es) | 1985-09-01 |
ES8507476A1 true ES8507476A1 (es) | 1985-09-01 |
Family
ID=10531083
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES523305A Expired ES8500220A1 (es) | 1982-06-16 | 1983-06-15 | Un procedimiento para la preparacion de nuevos derivados de amidina. |
ES529879A Expired ES8507476A1 (es) | 1982-06-16 | 1984-02-20 | Un procedimiento para la preparacion de nuevos benzonitrilos |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES523305A Expired ES8500220A1 (es) | 1982-06-16 | 1983-06-15 | Un procedimiento para la preparacion de nuevos derivados de amidina. |
Country Status (7)
Country | Link |
---|---|
US (2) | US4539319A (es) |
EP (1) | EP0097463A3 (es) |
JP (1) | JPS597151A (es) |
AU (1) | AU1575483A (es) |
DK (1) | DK273183A (es) |
ES (2) | ES8500220A1 (es) |
ZA (1) | ZA834347B (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8508588D0 (en) * | 1985-04-02 | 1985-05-09 | Akzo Nv | Indene & napthalene derivatives |
ATE231126T1 (de) * | 1993-08-12 | 2003-02-15 | Astrazeneca Ab | Amidin-derivate mit stickstoffoxid-synthease- aktivität |
US5869458A (en) * | 1994-10-14 | 1999-02-09 | Waite; Christopher S. | Frozen rehydration formulation and delivery system therefor |
WO1996041185A1 (en) * | 1995-06-07 | 1996-12-19 | Perseptive Biosystems, Inc. | Methods and compositions for binding endotoxins |
US6572898B2 (en) * | 1999-05-21 | 2003-06-03 | Pts Labs Llc | Electrolyte gels for maintaining hydration and rehydration |
EP1812042A1 (en) * | 2004-09-30 | 2007-08-01 | University Technologies International Inc. | Rehydration compositions comprising epidermal growth factor |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2491473A (en) * | 1948-11-16 | 1949-12-20 | Burroughs Wellcome Co | N-dialkyl alkoxynaphthamidines |
US2575991A (en) * | 1949-03-24 | 1951-11-20 | Burroughs Wellcome Co | Cinnamamidine derivatives |
US3259646A (en) * | 1963-05-13 | 1966-07-05 | Schering Corp | Process for the preparation of p-hydroxybenzonitrile |
EP0047817A3 (de) * | 1980-08-14 | 1982-05-26 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Hydrierte Naphthaline, deren Herstellung und Verwendung sowie derartige Naphthaline enthaltende Gemische |
-
1983
- 1983-06-10 EP EP83303362A patent/EP0097463A3/en not_active Withdrawn
- 1983-06-14 ZA ZA834347A patent/ZA834347B/xx unknown
- 1983-06-14 US US06/504,257 patent/US4539319A/en not_active Expired - Fee Related
- 1983-06-14 AU AU15754/83A patent/AU1575483A/en not_active Abandoned
- 1983-06-14 DK DK273183A patent/DK273183A/da not_active Application Discontinuation
- 1983-06-15 ES ES523305A patent/ES8500220A1/es not_active Expired
- 1983-06-16 JP JP58106833A patent/JPS597151A/ja active Pending
-
1984
- 1984-02-20 ES ES529879A patent/ES8507476A1/es not_active Expired
- 1984-12-21 US US06/684,630 patent/US4594195A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES529879A0 (es) | 1985-09-01 |
EP0097463A2 (en) | 1984-01-04 |
ES523305A0 (es) | 1984-10-01 |
ZA834347B (en) | 1984-04-25 |
US4539319A (en) | 1985-09-03 |
AU1575483A (en) | 1983-12-22 |
DK273183A (da) | 1983-12-17 |
ES8500220A1 (es) | 1984-10-01 |
US4594195A (en) | 1986-06-10 |
DK273183D0 (da) | 1983-06-14 |
JPS597151A (ja) | 1984-01-14 |
EP0097463A3 (en) | 1985-05-15 |
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