ES8500727A1 - Procedimiento para la obtencion de derivados de feniletilamina - Google Patents

Procedimiento para la obtencion de derivados de feniletilamina

Info

Publication number
ES8500727A1
ES8500727A1 ES525803A ES525803A ES8500727A1 ES 8500727 A1 ES8500727 A1 ES 8500727A1 ES 525803 A ES525803 A ES 525803A ES 525803 A ES525803 A ES 525803A ES 8500727 A1 ES8500727 A1 ES 8500727A1
Authority
ES
Spain
Prior art keywords
phenylethylemine
derivatires
growth stimulators
growth
stimulators
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES525803A
Other languages
English (en)
Other versions
ES525803A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19823234995 external-priority patent/DE3234995A1/de
Priority claimed from DE19833306159 external-priority patent/DE3306159A1/de
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES8500727A1 publication Critical patent/ES8500727A1/es
Publication of ES525803A0 publication Critical patent/ES525803A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/111—Aromatic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE FENILETILAMINA Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE X, Y, Z Y R1-R4 PUEDEN SER VARIOS RADICALES.CONSISTE EN LA REACCION DE REDUCCION DE UN COMPUESTO, DE FORMULA (II), EN LA QUE TODOS LOS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REDUCCION SE EFECTUA CON HIDRURO DE BORO Y SODIO EN MEDIO ACUOALCOHOLICO.TAMBIEN SE PUEDE HACER REACCIONAR UN COMPUESTO DE FORMULA (III) CON UNA AMINA DE FORMULA R2NHR3, EN LAS QUE TODOS LOS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I).ESTOS COMPUESTOS TIENEN APLICACIONES COMO ADITIVOS A PIENSOS PARA ANIMALES.
ES525803A 1982-09-22 1983-09-21 Procedimiento para la obtencion de derivados de feniletilamina Granted ES525803A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19823234995 DE3234995A1 (de) 1982-09-22 1982-09-22 Wachstumsfoerdernde phenylethylamin-derivate
DE19833306159 DE3306159A1 (de) 1983-02-22 1983-02-22 Wachstumsfoerdernde phenylethylamin-derivate

Publications (2)

Publication Number Publication Date
ES8500727A1 true ES8500727A1 (es) 1984-11-01
ES525803A0 ES525803A0 (es) 1984-11-01

Family

ID=25804617

Family Applications (1)

Application Number Title Priority Date Filing Date
ES525803A Granted ES525803A0 (es) 1982-09-22 1983-09-21 Procedimiento para la obtencion de derivados de feniletilamina

Country Status (9)

Country Link
EP (1) EP0103830A3 (es)
KR (1) KR840006327A (es)
AU (1) AU1924183A (es)
BR (1) BR8305192A (es)
DK (1) DK431683A (es)
ES (1) ES525803A0 (es)
FI (1) FI833360A (es)
GR (1) GR79733B (es)
PT (1) PT77338B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3306160A1 (de) * 1983-02-22 1984-08-23 Bayer Ag, 5090 Leverkusen Wachstumsfoerdernde aminophenylethylamin-derivate
ZW6584A1 (en) * 1983-04-18 1985-04-17 Glaxo Group Ltd Phenethanolamine derivatives
EP0142102B1 (en) * 1983-11-04 1987-09-23 Beecham Group Plc Tertiary amines
DE3409270A1 (de) * 1984-03-14 1985-09-19 Bayer Ag, 5090 Leverkusen Monosilylierte aminophenylethylamin-derivate, verfahren zu ihrer herstellung und ihre verwendung zur wachstumsfoerderung
US4767443A (en) * 1984-09-20 1988-08-30 Ciba-Geigy Corporation Antifungal and antibacterial diazine derivatives compositions, intermediates, and method of use therefor
PT82120B (en) * 1985-03-01 1988-06-16 Beecham Group Plc Process for preparing veterinary formulations containing ethanolamine derivatives
ATE48511T1 (de) * 1985-03-21 1989-12-15 American Cyanamid Co M-cyanphenethanolamine als tierwachstumsfoerderer und antilipogene mittel.
US4614746A (en) * 1985-03-21 1986-09-30 American Cyanamid Company 5-fluorobenzonitrile derivatives for increasing the lean meat to fat ratio and/or enhancing the growth rate of warm-blooded animals
IL79133A0 (en) * 1985-07-29 1986-09-30 American Cyanamid Co Continuous release phenylethanolamine derivative compositions
US5059422A (en) * 1985-07-29 1991-10-22 American Cyanamid Company Continuous release phenylethanolamine derivative compositions
US5169633A (en) * 1985-07-29 1992-12-08 American Cyanamid Company Continuous release phenylethanolamine derivative compositions
ATE61794T1 (de) * 1985-10-17 1991-04-15 American Cyanamid Co Anthranilonitrilderivate und verwandte verbindungen als nuetzliche stoffe zur wachstumsbeschleunigung, zur verbesserung der futterqualitaet und zur steigerung des fleisch/fett-verhaeltnisses bei warmbluetigen tieren.
US4863959A (en) * 1985-10-17 1989-09-05 American Cyanamid Company Anthranilonitrile derivatives as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals
DE3615293A1 (de) * 1986-05-06 1987-11-12 Bayer Ag Verwendung von heteroarylethylaminen zur leistungsfoerderung bei tieren, heteroarylethylamine und verfahren zu ihrer herstellung
HU203040B (en) * 1988-07-05 1991-05-28 Egyt Gyogyszervegyeszeti Gyar Process for producing weight-increasing composition containing 1-(3,5-dihydroxy-phenyl)-2-(terc-butyl-amino)-ethanol
FR2647310B1 (fr) * 1989-05-29 1992-01-17 Roussel Uclaf Utilisation de beta-adrenergiques pour la fabrication de compositions zootechniques
EP0488435A1 (en) * 1990-11-26 1992-06-03 Duphar International Research B.V Method of increasing the muscle/fat ratio in agricultural domestic animals
US5171753A (en) * 1991-05-15 1992-12-15 A. H. Robins Company, Incorporated Derivatives of 2-amino-1-phenylethanol having antiulcer activity
US5216029A (en) * 1991-11-26 1993-06-01 Eli Lilly And Company Fish production
WO1994000432A1 (en) * 1992-06-30 1994-01-06 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Anorectic epinephrine derivatives
SE9202218D0 (sv) * 1992-07-22 1992-07-22 Kabi Pharmacia Ab Pharmacologically active alfa-(tertiary-aminomethyl)-benzenemethanol derivatives, pharmaceutical composition containing them, therapeutical use thereof and processes for their preparation
US5776983A (en) * 1993-12-21 1998-07-07 Bristol-Myers Squibb Company Catecholamine surrogates useful as β3 agonists
US7709677B2 (en) 2001-01-31 2010-05-04 Glaxosmithkline Llc Process of preparing arylethanoldiamines
GB0102407D0 (en) 2001-01-31 2001-03-14 Glaxo Group Ltd Process

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2816059A (en) * 1956-03-07 1957-12-10 Lilly Co Eli N-[beta-(o-chlorophenyl)-beta-(hydroxy)-ethyl] isopropyl amine, salts thereof, and compositions containing same
US2938921A (en) * 1958-03-17 1960-05-31 Lilly Co Eli Nu-[beta-(3, 4-dichlorophenyl)-beta-hydroxyethyl] isopropylamine and salts
DE1275069B (de) * 1960-02-15 1968-08-14 Boehringer Sohn Ingelheim 1-(3', 5'-Dihydroxyphenyl)-1-hydroxy-2-isopropylaminoalkane und Verfahren zu ihrer Herstellung
BE626435A (es) * 1961-12-22
DK104465C (da) * 1962-09-12 1966-05-23 Ici Ltd Fremgangsmåde til fremstilling af 1-phenyl-2-alkylaminoalkanolderivater eller syreadditionssalte deraf.
DE1218464B (de) * 1962-09-17 1966-06-08 Farmaceutici Italia Verfahren zur Herstellung von 1-(3, 4-Dimethoxyphenyl)-2-tert.-butylamino-aethanol und dessen Salzen
NL298924A (es) * 1962-10-18
AT252213B (de) * 1963-10-09 1967-02-10 Bayer Ag Verfahren zur Herstellung von neuen N-Methyl-N-tert. butyl-1-phenyl-2-aminoäthanolen und/oder deren Salzen
GB1037658A (en) * 1964-07-02 1966-08-03 Boots Pure Drug Co Ltd Phenylethanolamine derivatives
FR1503517A (fr) * 1965-04-22 1967-12-01 Bayer Ag Procédé de fabrication de d-(-)-n-alcoyl-1-phényl-2-aminoéthanols
DE1493482A1 (de) * 1965-06-01 1969-01-16 Boehringer Sohn Ingelheim Verfahren zur Herstellung von 3,4-Dihydroxyphenylalkanolaminen
AT278751B (de) * 1966-07-14 1970-02-10 Pietro Pratesi Verfahren zur herstellung von neuen m- oder p-substituierten 1-phenylalkylaminoaethanol-(1)-salzen
GB1200886A (en) * 1966-09-23 1970-08-05 Allen & Hanburys Ltd Phenylaminoethanol derivatives
CH555831A (de) * 1967-02-17 1974-11-15 Scherico Ltd Verfahren zur herstellung von neuen benzazepinen.
GB1321701A (en) * 1969-10-01 1973-06-27 Continental Pharma Amino-alcohols their salts and process for prepairing the same
IT1044214B (it) * 1971-04-22 1980-03-20 Zambeletti Spa L 2 idrossi 2 feniletilamine so stituite dotate di proprieta vasoattive e processo per la loro preparazione
BE790604A (fr) * 1971-10-28 1973-04-26 Sandoz Sa Nouveaux aminoalcanols, leur preparation et leur application comme medicaments
OA04567A (fr) * 1972-11-30 1980-05-31 Rhone Poulenc Sa Nouveaux dérivés de l'imidazo (2,1-b) thiazole et leur préparation.
JPS5310974B2 (es) * 1974-06-10 1978-04-18
GB1561305A (en) * 1975-07-02 1980-02-20 Smithkline Corp Benzazepine derivatives and pharmeceutical compositions containing them
SE7510988L (sv) * 1975-10-01 1977-04-02 Draco Ab Nya farmaceutiskt aktiva foreningar
GB1535435A (en) * 1975-12-11 1978-12-13 Tanabe Seiyaku Co Benzyl alcohol derivatives
GB1555958A (en) * 1976-02-27 1979-11-14 Allen & Hanburys Ltd Amino hydroxyethyl salicylamides processes for their preparation and compositions containing them
DE2817494A1 (de) * 1977-05-03 1978-11-09 Continental Pharma Aminoalkohol-derivat
US4171359A (en) * 1978-04-12 1979-10-16 Smithkline Corporation Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
IL57669A0 (en) * 1978-07-03 1979-10-31 Lilly Co Eli R-n-(2-phenyl-2-hydroxyethyl)-3-phenylpropyl amines,formulations and method of treatment
IL60530A (en) * 1979-08-16 1984-10-31 American Cyanamid Co Animal feed compositions useful as growth promotors and for reduction of fat in animals,comprising phenylethanolamine derivatives and certain such novel compounds
FR2502145A2 (fr) * 1979-12-14 1982-09-24 Lafon Labor Derives de fluorophenacyl-amine et leur utilisation en therapeutique
EP0040000B1 (en) * 1980-05-08 1983-10-12 Beecham Group Plc Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions
US4340600A (en) * 1980-05-22 1982-07-20 Smithkline Corporation Renal dilating methods and compositions using 4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinolines
DE3175580D1 (en) * 1980-08-25 1987-01-02 American Cyanamid Co Method for enhancing the growth rate of meat-producing animals and for improving the lean meat to fat ratio thereof
DE3104850A1 (de) * 1981-02-11 1982-08-26 Dr. Karl Thomae Gmbh, 7950 Biberach "neuer futterzusatz zur verbesserung des wachstums"
EP0068669A1 (en) * 1981-06-20 1983-01-05 Beecham Group Plc Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application

Also Published As

Publication number Publication date
DK431683A (da) 1984-03-23
KR840006327A (ko) 1984-11-29
ES525803A0 (es) 1984-11-01
EP0103830A3 (de) 1985-07-31
AU1924183A (en) 1984-03-29
FI833360A0 (fi) 1983-09-20
PT77338B (en) 1986-03-11
FI833360A (fi) 1984-03-23
DK431683D0 (da) 1983-09-21
EP0103830A2 (de) 1984-03-28
PT77338A (en) 1983-10-01
BR8305192A (pt) 1984-11-13
GR79733B (es) 1984-10-31

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