ES8500220A1 - Un procedimiento para la preparacion de nuevos derivados de amidina. - Google Patents

Un procedimiento para la preparacion de nuevos derivados de amidina.

Info

Publication number
ES8500220A1
ES8500220A1 ES523305A ES523305A ES8500220A1 ES 8500220 A1 ES8500220 A1 ES 8500220A1 ES 523305 A ES523305 A ES 523305A ES 523305 A ES523305 A ES 523305A ES 8500220 A1 ES8500220 A1 ES 8500220A1
Authority
ES
Spain
Prior art keywords
hydrogen
image
enterotoxin
amidine derivatives
induced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES523305A
Other languages
English (en)
Other versions
ES523305A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES523305A0 publication Critical patent/ES523305A0/es
Publication of ES8500220A1 publication Critical patent/ES8500220A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/195Radicals derived from nitrogen analogues of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/21Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE AMIDINA, DE FORMULA GENERAL (I), Y SUS SALES DE ADICION DE ACIDOS.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL (II), CON UN COMPUESTO DE FORMULA GENERAL (III).DE APLICACION EN EL TRATAMIENTO DE LA DIARREA INDUCIDA POR ENTEROTOXINAS EN PERSONAS Y DE LA DIARREA BLANCA EN ANIMALES.
ES523305A 1982-06-16 1983-06-15 Un procedimiento para la preparacion de nuevos derivados de amidina. Expired ES8500220A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8217452 1982-06-16

Publications (2)

Publication Number Publication Date
ES523305A0 ES523305A0 (es) 1984-10-01
ES8500220A1 true ES8500220A1 (es) 1984-10-01

Family

ID=10531083

Family Applications (2)

Application Number Title Priority Date Filing Date
ES523305A Expired ES8500220A1 (es) 1982-06-16 1983-06-15 Un procedimiento para la preparacion de nuevos derivados de amidina.
ES529879A Expired ES8507476A1 (es) 1982-06-16 1984-02-20 Un procedimiento para la preparacion de nuevos benzonitrilos

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES529879A Expired ES8507476A1 (es) 1982-06-16 1984-02-20 Un procedimiento para la preparacion de nuevos benzonitrilos

Country Status (7)

Country Link
US (2) US4539319A (es)
EP (1) EP0097463A3 (es)
JP (1) JPS597151A (es)
AU (1) AU1575483A (es)
DK (1) DK273183A (es)
ES (2) ES8500220A1 (es)
ZA (1) ZA834347B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8508588D0 (en) * 1985-04-02 1985-05-09 Akzo Nv Indene & napthalene derivatives
ATE231126T1 (de) * 1993-08-12 2003-02-15 Astrazeneca Ab Amidin-derivate mit stickstoffoxid-synthease- aktivität
US5869458A (en) * 1994-10-14 1999-02-09 Waite; Christopher S. Frozen rehydration formulation and delivery system therefor
WO1996041185A1 (en) * 1995-06-07 1996-12-19 Perseptive Biosystems, Inc. Methods and compositions for binding endotoxins
US6572898B2 (en) 1999-05-21 2003-06-03 Pts Labs Llc Electrolyte gels for maintaining hydration and rehydration
WO2006034587A1 (en) * 2004-09-30 2006-04-06 University Technologies International, Inc. Rehydration compositions comprising epidermal growth factor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2491473A (en) * 1948-11-16 1949-12-20 Burroughs Wellcome Co N-dialkyl alkoxynaphthamidines
US2575991A (en) * 1949-03-24 1951-11-20 Burroughs Wellcome Co Cinnamamidine derivatives
US3259646A (en) * 1963-05-13 1966-07-05 Schering Corp Process for the preparation of p-hydroxybenzonitrile
EP0047817A3 (de) * 1980-08-14 1982-05-26 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Hydrierte Naphthaline, deren Herstellung und Verwendung sowie derartige Naphthaline enthaltende Gemische

Also Published As

Publication number Publication date
ES529879A0 (es) 1985-09-01
ES8507476A1 (es) 1985-09-01
EP0097463A3 (en) 1985-05-15
AU1575483A (en) 1983-12-22
US4539319A (en) 1985-09-03
JPS597151A (ja) 1984-01-14
ES523305A0 (es) 1984-10-01
ZA834347B (en) 1984-04-25
EP0097463A2 (en) 1984-01-04
DK273183A (da) 1983-12-17
US4594195A (en) 1986-06-10
DK273183D0 (da) 1983-06-14

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