ES8506684A1 - Procedimiento para preparar derivados reactivos de acido 2-(fur-2-il)-2-metoxiiiminoacetico - Google Patents
Procedimiento para preparar derivados reactivos de acido 2-(fur-2-il)-2-metoxiiiminoaceticoInfo
- Publication number
- ES8506684A1 ES8506684A1 ES533304A ES533304A ES8506684A1 ES 8506684 A1 ES8506684 A1 ES 8506684A1 ES 533304 A ES533304 A ES 533304A ES 533304 A ES533304 A ES 533304A ES 8506684 A1 ES8506684 A1 ES 8506684A1
- Authority
- ES
- Spain
- Prior art keywords
- general formula
- fur
- reaction
- cefuroxime
- manufacture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
- C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS REACTIVOS DE ACIDO 2-(FUR-2-IL)-2-METOXI-IMINOACETICO, DE FORMULA GENERAL (I), EN LA QUE R1 REPRESENTA UN GRUPO ALQUILO, ARILO, ARALQUILO, CICLOALQUILO O HETEROCICLICO, SUSTITUIDO O INSUSTITUIDOS.CONSISTE EN HACER REACCIONAR LA SAL DE ACIDO 2-(FUR-2-IL)-2-METOXIAMINOACETICO, DE FORMULA GENERAL (II) E, N LA QUE X ES UN METAL ALCALINO O ALCALINOTERRENO O UNA BASE ORGANICA, CON HALUROS SULFONICOS, DE FORMULA GENERAL (III), EN LA QUE R1 TIENE EL SIGNIFICADO YA MENCIONADO; E Y ES UN ATOMO DE HALOGENO, EFECTUANDOSE DICHA REACCION EN UN DISOLVENTE POLAR Y A BAJA TEMPERATURA.DE APLICACION EN FARMACIA Y MEDICINA COMO ANTIBIOTICOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8220099A IT1190734B (it) | 1982-03-11 | 1982-03-11 | Procedimento per la preparazione di cefuroxima e intermedi impiegati in tale procedimento |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8506684A1 true ES8506684A1 (es) | 1985-08-01 |
ES533304A0 ES533304A0 (es) | 1985-08-01 |
Family
ID=11163788
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES520477A Expired ES8407494A1 (es) | 1982-03-11 | 1983-03-10 | Procedimiento para preparar el antibiotico cefuroxima. |
ES533304A Granted ES533304A0 (es) | 1982-03-11 | 1984-06-11 | Procedimiento para preparar derivados reactivos de acido 2-(fur-2-il)-2-metoxiiiminoacetico |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES520477A Expired ES8407494A1 (es) | 1982-03-11 | 1983-03-10 | Procedimiento para preparar el antibiotico cefuroxima. |
Country Status (4)
Country | Link |
---|---|
JP (1) | JPH0662636B2 (es) |
KR (1) | KR900006810B1 (es) |
ES (2) | ES8407494A1 (es) |
IT (1) | IT1190734B (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100669507B1 (ko) * | 2000-08-01 | 2007-01-16 | 보령제약 주식회사 | 세푸록심의 제조방법 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1453049A (en) * | 1973-08-21 | 1976-10-20 | Glaxo Lab Ltd | Cephalosporing antibiotics |
FR2462439A1 (fr) * | 1979-07-26 | 1981-02-13 | Roussel Uclaf | Nouveau procede de preparation de produits derives de l'acide 7-/(2-aryl) 2-hydroxyimino acetamido/cephalosporanique |
-
1982
- 1982-03-11 IT IT8220099A patent/IT1190734B/it active
-
1983
- 1983-03-10 ES ES520477A patent/ES8407494A1/es not_active Expired
- 1983-03-11 JP JP58039361A patent/JPH0662636B2/ja not_active Expired - Lifetime
- 1983-03-11 KR KR1019830000981A patent/KR900006810B1/ko not_active IP Right Cessation
-
1984
- 1984-06-11 ES ES533304A patent/ES533304A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
ES520477A0 (es) | 1984-10-01 |
KR840004114A (ko) | 1984-10-06 |
IT1190734B (it) | 1988-02-24 |
JPH0662636B2 (ja) | 1994-08-17 |
KR900006810B1 (ko) | 1990-09-21 |
ES8407494A1 (es) | 1984-10-01 |
IT8220099A0 (it) | 1982-03-11 |
JPS58167593A (ja) | 1983-10-03 |
ES533304A0 (es) | 1985-08-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20000301 |