ES8506662A1 - Procedimiento para la preparacion de derivados de naftaleniltiazol - Google Patents

Procedimiento para la preparacion de derivados de naftaleniltiazol

Info

Publication number
ES8506662A1
ES8506662A1 ES525726A ES525726A ES8506662A1 ES 8506662 A1 ES8506662 A1 ES 8506662A1 ES 525726 A ES525726 A ES 525726A ES 525726 A ES525726 A ES 525726A ES 8506662 A1 ES8506662 A1 ES 8506662A1
Authority
ES
Spain
Prior art keywords
derivatives
naphthalenylthiazole
halo
image
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES525726A
Other languages
English (en)
Other versions
ES525726A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Canada Inc
Original Assignee
Ayerst Mckenna and Harrison Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ayerst Mckenna and Harrison Inc filed Critical Ayerst Mckenna and Harrison Inc
Publication of ES525726A0 publication Critical patent/ES525726A0/es
Publication of ES8506662A1 publication Critical patent/ES8506662A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE NAFTALENILTIAZOL.COMPRENDE: CICLIZAR UN COMPUESTO DE FORMULA (II) EN PRESENCIA DE UN ANHIDRIDO DE ACIDO ALCANOICO INFERIOR Y DE UN RECEPTOR DE PROTONES, PARA OBTENER DERIVADOS DE NAFTALENILTIAZOL DE FORMULA (I), EN DONDE R ES UN COMPUESTO DE FORMULA (III) EN DONDE R1 ES ALQUILO INFERIOR; R2 ES HALO EN EL ANILLO NAFTALENICO Y R3 ES H O R2 Y R3 CON UN SUSTITUYENTE EN POSICIONES 3, 4, 5 O 6 DEL ANILLO NAFTALENICO.SE UTILIZAN PARA EL TRATAMIENTO DE DIABETES MELLITUS.
ES525726A 1982-09-21 1983-09-19 Procedimiento para la preparacion de derivados de naftaleniltiazol Expired ES8506662A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/420,776 US4446150A (en) 1982-09-21 1982-09-21 Naphthalenylthiazole derivatives

Publications (2)

Publication Number Publication Date
ES525726A0 ES525726A0 (es) 1985-08-16
ES8506662A1 true ES8506662A1 (es) 1985-08-16

Family

ID=23667801

Family Applications (2)

Application Number Title Priority Date Filing Date
ES525726A Expired ES8506662A1 (es) 1982-09-21 1983-09-19 Procedimiento para la preparacion de derivados de naftaleniltiazol
ES541712A Granted ES541712A0 (es) 1982-09-21 1985-03-29 Procedimiento para la preparacion de derivados de nagtaleniltiazol.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES541712A Granted ES541712A0 (es) 1982-09-21 1985-03-29 Procedimiento para la preparacion de derivados de nagtaleniltiazol.

Country Status (12)

Country Link
US (1) US4446150A (es)
EP (1) EP0104078B1 (es)
JP (1) JPS5976075A (es)
AT (1) ATE35542T1 (es)
AU (1) AU1895383A (es)
CA (1) CA1211116A (es)
DE (1) DE3377279D1 (es)
DK (1) DK429283A (es)
ES (2) ES8506662A1 (es)
GR (1) GR79051B (es)
SU (1) SU1205767A3 (es)
ZA (1) ZA836680B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4492706A (en) * 1983-08-01 1985-01-08 American Home Products Corporation Method of lowering lipid levels
CA1307537C (en) * 1987-12-23 1992-09-15 Jay E. Wrobel N-naphthoylglycines as aldose reductase inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2474426A (en) * 1941-12-10 1949-06-28 Ilford Ltd Cyanine dyestuffs and dyestuff intermediates
US2441558A (en) * 1945-10-16 1948-05-18 Eastman Kodak Co Process for preparing nu-arylthiazolinium quaternary salts
US3436397A (en) * 1966-05-23 1969-04-01 American Home Prod Dibenzocyclohepten-5-ylidene thiazolidinones
US3436398A (en) * 1966-05-23 1969-04-01 American Home Prod Benzhydrylidene thiazolidinones
US3539585A (en) * 1968-10-03 1970-11-10 American Home Prod 4-hydroxy-2-thiazoline-5-alkanoic acids
US4260609A (en) * 1977-06-01 1981-04-07 Merck & Co., Inc. Di- and tri- substituted thiazoles
AU544067B2 (en) * 1981-03-02 1985-05-16 Wyeth-Ayerst Canada Inc. Thioamides and amides. treatment of diabetes

Also Published As

Publication number Publication date
ES8602711A1 (es) 1985-12-01
GR79051B (es) 1984-10-02
DE3377279D1 (de) 1988-08-11
EP0104078A2 (en) 1984-03-28
DK429283D0 (da) 1983-09-20
JPH0479344B2 (es) 1992-12-15
AU1895383A (en) 1984-03-29
ATE35542T1 (de) 1988-07-15
EP0104078B1 (en) 1988-07-06
EP0104078A3 (en) 1985-09-25
ES541712A0 (es) 1985-12-01
ES525726A0 (es) 1985-08-16
DK429283A (da) 1984-03-22
CA1211116A (en) 1986-09-09
JPS5976075A (ja) 1984-04-28
US4446150A (en) 1984-05-01
SU1205767A3 (ru) 1986-01-15
ZA836680B (en) 1985-04-24

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