DE3377279D1 - Naphthalenylthiazole derivatives - Google Patents

Naphthalenylthiazole derivatives

Info

Publication number
DE3377279D1
DE3377279D1 DE8383305503T DE3377279T DE3377279D1 DE 3377279 D1 DE3377279 D1 DE 3377279D1 DE 8383305503 T DE8383305503 T DE 8383305503T DE 3377279 T DE3377279 T DE 3377279T DE 3377279 D1 DE3377279 D1 DE 3377279D1
Authority
DE
Germany
Prior art keywords
sup
derivatives
naphthalenylthiazole
halo
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383305503T
Other languages
English (en)
Inventor
Kazimir Sestanj
Francesco Bellini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Canada Inc
Original Assignee
Ayerst Mckenna and Harrison Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ayerst Mckenna and Harrison Inc filed Critical Ayerst Mckenna and Harrison Inc
Application granted granted Critical
Publication of DE3377279D1 publication Critical patent/DE3377279D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8383305503T 1982-09-21 1983-09-20 Naphthalenylthiazole derivatives Expired DE3377279D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/420,776 US4446150A (en) 1982-09-21 1982-09-21 Naphthalenylthiazole derivatives

Publications (1)

Publication Number Publication Date
DE3377279D1 true DE3377279D1 (de) 1988-08-11

Family

ID=23667801

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383305503T Expired DE3377279D1 (de) 1982-09-21 1983-09-20 Naphthalenylthiazole derivatives

Country Status (12)

Country Link
US (1) US4446150A (de)
EP (1) EP0104078B1 (de)
JP (1) JPS5976075A (de)
AT (1) ATE35542T1 (de)
AU (1) AU1895383A (de)
CA (1) CA1211116A (de)
DE (1) DE3377279D1 (de)
DK (1) DK429283A (de)
ES (2) ES8506662A1 (de)
GR (1) GR79051B (de)
SU (1) SU1205767A3 (de)
ZA (1) ZA836680B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4492706A (en) * 1983-08-01 1985-01-08 American Home Products Corporation Method of lowering lipid levels
CA1307537C (en) * 1987-12-23 1992-09-15 Jay E. Wrobel N-naphthoylglycines as aldose reductase inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2474426A (en) * 1941-12-10 1949-06-28 Ilford Ltd Cyanine dyestuffs and dyestuff intermediates
US2441558A (en) * 1945-10-16 1948-05-18 Eastman Kodak Co Process for preparing nu-arylthiazolinium quaternary salts
US3436397A (en) * 1966-05-23 1969-04-01 American Home Prod Dibenzocyclohepten-5-ylidene thiazolidinones
US3436398A (en) * 1966-05-23 1969-04-01 American Home Prod Benzhydrylidene thiazolidinones
US3539585A (en) * 1968-10-03 1970-11-10 American Home Prod 4-hydroxy-2-thiazoline-5-alkanoic acids
US4260609A (en) * 1977-06-01 1981-04-07 Merck & Co., Inc. Di- and tri- substituted thiazoles
AU544067B2 (en) * 1981-03-02 1985-05-16 Wyeth-Ayerst Canada Inc. Thioamides and amides. treatment of diabetes

Also Published As

Publication number Publication date
ES8602711A1 (es) 1985-12-01
GR79051B (de) 1984-10-02
EP0104078A2 (de) 1984-03-28
DK429283D0 (da) 1983-09-20
JPH0479344B2 (de) 1992-12-15
AU1895383A (en) 1984-03-29
ATE35542T1 (de) 1988-07-15
EP0104078B1 (de) 1988-07-06
EP0104078A3 (en) 1985-09-25
ES541712A0 (es) 1985-12-01
ES525726A0 (es) 1985-08-16
DK429283A (da) 1984-03-22
ES8506662A1 (es) 1985-08-16
CA1211116A (en) 1986-09-09
JPS5976075A (ja) 1984-04-28
US4446150A (en) 1984-05-01
SU1205767A3 (ru) 1986-01-15
ZA836680B (en) 1985-04-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee