ES8506450A1 - Procedimiento para higienizar o pasterizar fribrinogeno humano - Google Patents

Procedimiento para higienizar o pasterizar fribrinogeno humano

Info

Publication number
ES8506450A1
ES8506450A1 ES524992A ES524992A ES8506450A1 ES 8506450 A1 ES8506450 A1 ES 8506450A1 ES 524992 A ES524992 A ES 524992A ES 524992 A ES524992 A ES 524992A ES 8506450 A1 ES8506450 A1 ES 8506450A1
Authority
ES
Spain
Prior art keywords
human fibrinogen
preparing
pasteurized human
aqueous solution
pasteurized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES524992A
Other languages
English (en)
Other versions
ES524992A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6171221&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8506450(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Behringwerke AG filed Critical Behringwerke AG
Publication of ES524992A0 publication Critical patent/ES524992A0/es
Publication of ES8506450A1 publication Critical patent/ES8506450A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/363—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/04—Heat

Abstract

PROCEDIMIENTO PARA HIGIENIZAR O PASTERIZAR FIBRINOGENO HUMANO.CONSISTENTE EN AN/ADIR A UNA SOLUCION DE FIBRINOGENO, CON PH ENTRE 6 Y 8, IONES CALCIO EN UNA CONCETRACION DE 1 A 37,8.103 ATOMOS-GRAMO POR MOL DE FIBRINOGENO, AGREGANDO SACAROSA HASTA ALCANZAR UNA CONCETRACION DE 35 A 60G/100ML DE SOLUCION, Y GLICINA ENTRE 0,5 Y 3 MOLES/LITRO, AJUSTANDOSE EL PH ENTRE 6 Y 8. LA SOLUCION SE CALIENTA ENTRE 60JC Y 100C DURANTE UN TIEMPO COMPRENDIDO ENTRE 10 HORAS Y 24 HORAS. EL FIBRINOGENO RESULTA EXENTO DE POLIMERO Y POSEE BUENA SOLUBILIDAD.UTILIZABLE COMO SOLUCION PARA INFUSION EN PROPORCION DE 2 PESO/VOLUMEN O COMO PEGAMENTO PARA TEJIDOS CON UNA PROPORCION DE 10 PESO/VOLUMEN.
ES524992A 1982-08-19 1983-08-17 Procedimiento para higienizar o pasterizar fribrinogeno humano Expired ES8506450A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3230849A DE3230849A1 (de) 1982-08-19 1982-08-19 Pasteurisiertes human-fibrinogen (hf) und verfahren zu dessen herstellung

Publications (2)

Publication Number Publication Date
ES524992A0 ES524992A0 (es) 1985-08-01
ES8506450A1 true ES8506450A1 (es) 1985-08-01

Family

ID=6171221

Family Applications (1)

Application Number Title Priority Date Filing Date
ES524992A Expired ES8506450A1 (es) 1982-08-19 1983-08-17 Procedimiento para higienizar o pasterizar fribrinogeno humano

Country Status (14)

Country Link
US (1) US4960757A (es)
EP (1) EP0103196B2 (es)
JP (1) JPH0694419B2 (es)
AT (1) ATE47525T1 (es)
AU (1) AU587365B2 (es)
CA (1) CA1203166A (es)
DE (2) DE3230849A1 (es)
ES (1) ES8506450A1 (es)
GR (1) GR78934B (es)
IL (1) IL69515A (es)
NO (1) NO159698C (es)
NZ (1) NZ205306A (es)
PT (1) PT77213B (es)
ZA (1) ZA836093B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3336631A1 (de) * 1983-10-08 1985-04-18 Behringwerke Ag, 3550 Marburg Verfahren zur pasteurisierung von plasma oder von konzentraten der blutgerinnungsfaktoren ii, vii, ix und x
AT390001B (de) * 1984-09-28 1990-03-12 Immuno Ag Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern
DE3622642A1 (de) * 1986-07-05 1988-01-14 Behringwerke Ag Einkomponenten-gewebekleber sowie verfahren zu seiner herstellung
JP2526073B2 (ja) * 1987-10-06 1996-08-21 株式会社ミドリ十字 異常破水治療剤
AT407834B (de) * 1987-10-08 2001-06-25 Aventis Behring Gmbh Einkomponenten-gewebekleber sowie verfahren zu seiner herstellung
FR2650508A1 (fr) * 1989-08-01 1991-02-08 Fondation Nale Transfusion San Colle pasteurisee pour reunir des tissus humain ou animal
US5420250A (en) * 1990-08-06 1995-05-30 Fibrin Corporation Phase transfer process for producing native plasma protein concentrates
US5644032A (en) * 1990-08-06 1997-07-01 Fibrin Corporation Process for producing fibrinogen concentrates
DE4202667C1 (es) * 1992-01-29 1993-05-13 Behringwerke Ag, 3550 Marburg, De
FR2687317B1 (fr) * 1992-02-13 1995-06-23 Aetsrn Composition pour stabiliser le plasma sanguin en cour de pasteurisation et solution plasmatique pasteurisee a usage therapeutique.
US5385606A (en) * 1992-07-06 1995-01-31 Kowanko; Nicholas Adhesive composition and method
AU4693093A (en) * 1992-07-27 1994-02-14 Haemacure Biotech Inc. Biocompatible surgical implant
CN1091315A (zh) * 1992-10-08 1994-08-31 E·R·斯奎布父子公司 血纤维蛋白封闭剂组合物及其使用方法
WO1995026749A1 (en) * 1994-03-31 1995-10-12 Fibrin Corporation Cryoprecipitated native fibrinogen concentrates
PT2130554E (pt) 1999-02-22 2012-11-19 Univ Connecticut Formulações de factor viii isentas de albumina
EP1202754B1 (en) * 1999-08-13 2003-10-29 Omrix Biopharmaceuticals S.A. Use of fibrinogen multimers in fibrin sealants
US6916911B1 (en) 1999-08-13 2005-07-12 Omrix Biopharmaceuticals Sa Use of fibrinogen multimers
NZ518692A (en) * 1999-12-23 2004-08-27 Csl Ltd Purified fibrinogen free of destabilising levels of plasminogen and other proteases obtained from a Fraction I paste
JP4733283B2 (ja) * 2000-03-28 2011-07-27 一般財団法人化学及血清療法研究所 液状フィブリノゲン製剤
DE10022092A1 (de) * 2000-05-08 2001-11-15 Aventis Behring Gmbh Stabilisiertes Protein-Präparat und Verfahren zu seiner Herstellung
DE10261126A1 (de) 2002-08-13 2004-03-04 Aventis Behring Gmbh Lagerungsstabile, flüssige Fibrinogen-Formulierung
DE102004009400A1 (de) * 2004-02-24 2005-09-08 Zlb Behring Gmbh Fibrinogen Reinigung
DE102004037805B3 (de) * 2004-08-03 2006-03-23 Zlb Behring Gmbh Verfahren zur Hitzebehandlung fibrinogenhaltiger pharmazeutischer Zubereitungen
US20100168018A1 (en) * 2008-11-07 2010-07-01 Baxter International Inc. Factor viii formulations
US10112972B2 (en) 2012-03-13 2018-10-30 Octapharma Ag Process for production of fibrinogen and fibrinogen produced thereby
RU2556804C2 (ru) * 2013-12-17 2015-07-20 Федеральное государственное бюджетное учреждение Гематологический научный центр Министерства здравоохранения РФ Способ получения концентрата фибриногена

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2916711A1 (de) * 1979-04-25 1980-11-06 Behringwerke Ag Blutgerinnungsfaktoren und verfahren zu ihrer herstellung
DE3176491D1 (en) * 1980-03-05 1987-11-26 Miles Lab Pasteurized therapeutically active protein compositions
US4440679A (en) * 1980-03-05 1984-04-03 Cutter Laboratories, Inc. Pasteurized therapeutically active protein compositions
JPS56135418A (en) * 1980-03-27 1981-10-22 Green Cross Corp:The Heat treatment of aqueous solution containing 8 factor of coagulation of blood derived from human
DE3045153A1 (de) * 1980-11-29 1982-07-08 Behringwerke Ag, 3550 Marburg Verfahren zur herstellung von blutgerinnungsfaktoren und danach hergestellte praeparation der faktoren ix und x
DE3101752A1 (de) * 1981-01-21 1982-08-26 Behringwerke Ag, 3550 Marburg "verfahren zur reinigung der blutgerinnungsfaktoren ii, vii, ix und/oder x und danach hergestellte praeparationen"
US4456590B2 (en) * 1981-11-02 1989-05-30 Heat treatment of lyphilized blood clotting factor viii concentrate

Also Published As

Publication number Publication date
JPS5953428A (ja) 1984-03-28
PT77213A (de) 1983-09-01
EP0103196B1 (de) 1989-10-25
GR78934B (es) 1984-10-02
ES524992A0 (es) 1985-08-01
EP0103196A3 (en) 1985-05-08
IL69515A (en) 1987-01-30
DE3380764D1 (en) 1989-11-30
EP0103196A2 (de) 1984-03-21
NO159698C (no) 1989-02-01
CA1203166A (en) 1986-04-15
DE3230849A1 (de) 1984-02-23
PT77213B (de) 1986-03-18
NZ205306A (en) 1987-02-20
ATE47525T1 (de) 1989-11-15
IL69515A0 (en) 1983-11-30
JPH0694419B2 (ja) 1994-11-24
NO159698B (no) 1988-10-24
AU1810983A (en) 1984-02-23
AU587365B2 (en) 1989-08-17
ZA836093B (en) 1984-04-25
US4960757A (en) 1990-10-02
EP0103196B2 (de) 1994-10-12
NO832977L (no) 1984-02-20

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Legal Events

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PC1A Transfer granted
FD1A Patent lapsed

Effective date: 20040601