ES8506259A1 - Procedimiento para la obtencion de 1, 3-bis (dimetilamino)-2-propil-4-clorofenoxi acetato - Google Patents

Procedimiento para la obtencion de 1, 3-bis (dimetilamino)-2-propil-4-clorofenoxi acetato

Info

Publication number
ES8506259A1
ES8506259A1 ES532062A ES532062A ES8506259A1 ES 8506259 A1 ES8506259 A1 ES 8506259A1 ES 532062 A ES532062 A ES 532062A ES 532062 A ES532062 A ES 532062A ES 8506259 A1 ES8506259 A1 ES 8506259A1
Authority
ES
Spain
Prior art keywords
dimethylamino
bis
chlorophenoxyacetate
propyl
addition salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES532062A
Other languages
English (en)
Other versions
ES532062A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Works PLC
Original Assignee
Biogal Gyogyszergyar Rt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogal Gyogyszergyar Rt filed Critical Biogal Gyogyszergyar Rt
Publication of ES532062A0 publication Critical patent/ES532062A0/es
Publication of ES8506259A1 publication Critical patent/ES8506259A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C219/20—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C219/22—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Detergent Compositions (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Photoreceptors In Electrophotography (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE 1,3-BIS (DIMETILAMINO)-2-PROPIL-4-CLOROFENOXIACETATO.COMPRENDE: HACER REACCIONAR UN COMPUESTO DE FORMULA (II), EN DONDE R ES UN GRUPO CARBOXILO, CIANO U OTROS, CON UN COMPUESTO DE FORMULA (III), EN DONDE R ES UN GRUPO HIDROXILO O HALOGENO; Y AISLAR EL COMPUESTO OBTENIDO PARA PRODUCIR EL COMPUESTO DE FORMULA (I) Y SUS SALES DE ADICION DE ACIDO FARMACOLOGICAMENTE COMPATIBLES.SE UTILIZA COMO NEUROESTIMULANTE.
ES532062A 1983-05-02 1984-04-30 Procedimiento para la obtencion de 1, 3-bis (dimetilamino)-2-propil-4-clorofenoxi acetato Expired ES8506259A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU831496A HU190589B (en) 1983-05-02 1983-05-02 Process for preparing acid additional salts of 4-chloro-phenoxy-acetic acid-1,3-bis/dimethyl-amino/-2-propyl-ester

Publications (2)

Publication Number Publication Date
ES532062A0 ES532062A0 (es) 1985-07-01
ES8506259A1 true ES8506259A1 (es) 1985-07-01

Family

ID=10954727

Family Applications (1)

Application Number Title Priority Date Filing Date
ES532062A Expired ES8506259A1 (es) 1983-05-02 1984-04-30 Procedimiento para la obtencion de 1, 3-bis (dimetilamino)-2-propil-4-clorofenoxi acetato

Country Status (20)

Country Link
US (1) US4661618A (es)
EP (1) EP0127000B1 (es)
JP (1) JPS606646A (es)
KR (1) KR840009292A (es)
AT (1) ATE24712T1 (es)
AU (1) AU565723B2 (es)
BG (1) BG42833A3 (es)
CA (1) CA1246602A (es)
CS (1) CS241081B2 (es)
DD (1) DD216449A5 (es)
DE (1) DE3461924D1 (es)
DK (1) DK214884A (es)
EG (1) EG16744A (es)
ES (1) ES8506259A1 (es)
FI (1) FI81562C (es)
HU (1) HU190589B (es)
IL (1) IL71714A (es)
NZ (1) NZ208011A (es)
PL (1) PL142906B1 (es)
SU (2) SU1376937A3 (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3546273A (en) * 1967-06-01 1970-12-08 Merck & Co Inc Ester derivatives of 2-(4-halophenoxy)alkanoic acids
JPS5135896B2 (es) * 1973-06-20 1976-10-05

Also Published As

Publication number Publication date
CA1246602A (en) 1988-12-13
ES532062A0 (es) 1985-07-01
FI841611A (fi) 1984-11-03
HUT34150A (en) 1985-02-28
DK214884A (da) 1984-11-03
AU2761084A (en) 1984-11-08
AU565723B2 (en) 1987-09-24
SU1376937A3 (ru) 1988-02-23
CS241081B2 (en) 1986-03-13
PL247504A1 (en) 1985-03-26
FI81562C (fi) 1990-11-12
HU190589B (en) 1986-09-29
EP0127000B1 (de) 1987-01-07
NZ208011A (en) 1987-06-30
IL71714A0 (en) 1984-09-30
IL71714A (en) 1987-09-16
ATE24712T1 (de) 1987-01-15
KR840009292A (ko) 1984-12-26
FI81562B (fi) 1990-07-31
BG42833A3 (en) 1988-02-15
US4661618A (en) 1987-04-28
SU1326572A1 (ru) 1987-07-30
JPS606646A (ja) 1985-01-14
PL142906B1 (en) 1987-12-31
CS321784A2 (en) 1985-06-13
JPH0527616B2 (es) 1993-04-21
EP0127000A1 (de) 1984-12-05
FI841611A0 (fi) 1984-04-24
DD216449A5 (de) 1984-12-12
DK214884D0 (da) 1984-04-27
EG16744A (en) 1990-12-30
DE3461924D1 (en) 1987-02-12

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19991108