ES8504681A1 - Procedimiento de preparacion de nuevos derivados de 4-benzalquilamido-2-carbalcoxifenoxiamino-propanol. - Google Patents

Procedimiento de preparacion de nuevos derivados de 4-benzalquilamido-2-carbalcoxifenoxiamino-propanol.

Info

Publication number
ES8504681A1
ES8504681A1 ES530503A ES530503A ES8504681A1 ES 8504681 A1 ES8504681 A1 ES 8504681A1 ES 530503 A ES530503 A ES 530503A ES 530503 A ES530503 A ES 530503A ES 8504681 A1 ES8504681 A1 ES 8504681A1
Authority
ES
Spain
Prior art keywords
branched
atom
formula
lower alkyl
alkyl radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES530503A
Other languages
English (en)
Other versions
ES530503A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Carpibem SA
Original Assignee
Carpibem SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8304150A external-priority patent/FR2542737B1/fr
Priority claimed from FR8318509A external-priority patent/FR2555169B2/fr
Application filed by Carpibem SA filed Critical Carpibem SA
Publication of ES8504681A1 publication Critical patent/ES8504681A1/es
Publication of ES530503A0 publication Critical patent/ES530503A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE 4-BENZALQUILAMIDO-2-CARBALCOXI-FENOXIAMINO-PROPANOL, DE FORMULA GENERAL (I), EN LA QUE R Y R PUEDEN SER CADA UNO DE ELLOS UN ATOMO DE HIDROGENO O DE HALOGENO; R1 REPRESENTA UN RADICAL ALQUILO INFERIOR C1-5; R2 REPRESENTA UN RADICAL ALQUILO INFERIOR C1-5; Y N ES UN NUMERO ENTERO INFERIOR A 5, Y SUS SALES FARMACEUTICAMENTE ACEPTABLES.CONSISTE EN HACER REACCIONAR UNA BASE DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), EN UN DISOLVENTE HABITUAL TAL COMO LOS ALCOHOLES, A UNA TEMPERATURA COMPRENDIDA ENTRE 20 Y 150 GRADOS.DE APLICACION EN TERAPEUTICA PARA EL TRATAMIENTO DE LA HIPERTENSION.
ES530503A 1983-03-14 1984-03-12 Procedimiento de preparacion de nuevos derivados de 4-benzalquilamido-2-carbalcoxifenoxiamino-propanol. Granted ES530503A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8304150A FR2542737B1 (fr) 1983-03-14 1983-03-14 Nouveaux (carbethoxy-2 benzalkylamido-4 phenoxy)-1 amino-3 propanols-2, leurs preparations et leurs utilisations en therapeutique
FR8318509A FR2555169B2 (fr) 1983-11-21 1983-11-21 Nouveaux (carbethoxy-2 benzalkylamido-4 phenoxyl)-1 amino-3 propanols-2, leurs preparations et leurs utilisations en therapeutique

Publications (2)

Publication Number Publication Date
ES8504681A1 true ES8504681A1 (es) 1985-05-01
ES530503A0 ES530503A0 (es) 1985-05-01

Family

ID=26223333

Family Applications (1)

Application Number Title Priority Date Filing Date
ES530503A Granted ES530503A0 (es) 1983-03-14 1984-03-12 Procedimiento de preparacion de nuevos derivados de 4-benzalquilamido-2-carbalcoxifenoxiamino-propanol.

Country Status (12)

Country Link
EP (1) EP0122827B1 (es)
KR (1) KR910002945B1 (es)
AT (1) ATE20879T1 (es)
AU (1) AU567332B2 (es)
CA (1) CA1218378A (es)
DE (1) DE3460323D1 (es)
DK (1) DK117484A (es)
ES (1) ES530503A0 (es)
GR (1) GR81821B (es)
IE (1) IE57094B1 (es)
PH (1) PH19184A (es)
PT (1) PT78238B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0617020A1 (en) * 1992-04-02 1994-09-28 Shudo, Koichi, Prof. Dr. Carboxylic acid derivatives having retinoic acid-like activity
JP3854154B2 (ja) * 2000-04-19 2006-12-06 ニューロテック カンパニー リミテッド 中枢神経系の急性及び慢性的損傷に起因した神経変性を防止するための化合物、組成物及び方法
US6573402B1 (en) 2000-04-20 2003-06-03 Neurotech Co., Ltd. Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system
EP1551793B1 (en) 2002-06-19 2016-01-20 AmKor Pharma, Inc. Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same
KR101333753B1 (ko) 2006-04-13 2013-11-28 주식회사 아라온테크 세포 손상 및 염증 질환의 치료 또는 예방용 약학 조성물
KR100852962B1 (ko) 2007-11-12 2008-08-20 주식회사 뉴로테크 2-하이드록시-5-페닐알킬아미노벤조산 유도체 및 이의 염의제조방법
CA2708804C (en) 2007-12-14 2016-01-12 3M Innovative Properties Company Fiber aggregate
EA021092B1 (ru) 2007-12-14 2015-04-30 Шлюмбергер Текнолоджи Б.В. Способ обработки подземных скважин с использованием изменяемых добавок
MX2010006456A (es) 2007-12-14 2010-09-28 Schlumberger Technology Bv Materiales de consolidacion y usos de los mismos.
KR101204108B1 (ko) * 2009-02-09 2012-11-22 주식회사 지엔티파마 5-벤질아미노살리실산 유도체 또는 이의 염의 의약 용도

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3852468A (en) * 1967-02-27 1974-12-03 Ici Ltd Alkanolamine derivatives as {62 -adrenergic blocking agents
MX158644A (es) * 1982-07-20 1989-02-21 Menarini Sas Procedimiento para preparar un derivado 1-alquilamina-3-(4(p-alquiloxibenzamida)-fenoxi)-2propanol

Also Published As

Publication number Publication date
DE3460323D1 (en) 1986-08-28
EP0122827B1 (fr) 1986-07-23
DK117484A (da) 1984-09-15
IE840528L (en) 1984-09-14
AU567332B2 (en) 1987-11-19
CA1218378A (en) 1987-02-24
AU2553784A (en) 1984-09-20
IE57094B1 (en) 1992-04-22
EP0122827A1 (fr) 1984-10-24
PH19184A (en) 1986-01-23
PT78238B (fr) 1986-04-24
DK117484D0 (da) 1984-02-28
PT78238A (fr) 1984-04-01
KR910002945B1 (ko) 1991-05-11
GR81821B (es) 1984-12-12
ATE20879T1 (de) 1986-08-15
KR840009078A (ko) 1984-12-24
ES530503A0 (es) 1985-05-01

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960401