ES8502429A1 - Procedimiento para la preparacion de n-acetil-4-triazolidincarboxilato de guayacol - Google Patents
Procedimiento para la preparacion de n-acetil-4-triazolidincarboxilato de guayacolInfo
- Publication number
- ES8502429A1 ES8502429A1 ES524727A ES524727A ES8502429A1 ES 8502429 A1 ES8502429 A1 ES 8502429A1 ES 524727 A ES524727 A ES 524727A ES 524727 A ES524727 A ES 524727A ES 8502429 A1 ES8502429 A1 ES 8502429A1
- Authority
- ES
- Spain
- Prior art keywords
- antitussive
- novel compound
- promotive
- fluidization
- mucus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000000954 anitussive effect Effects 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 229940124584 antitussives Drugs 0.000 title 1
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 title 1
- 238000005243 fluidization Methods 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 210000003097 mucus Anatomy 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000001737 promoting effect Effects 0.000 title 1
- 230000028327 secretion Effects 0.000 title 1
- LHGVFZTZFXWLCP-UHFFFAOYSA-N guaiacol Chemical compound COC1=CC=CC=C1O LHGVFZTZFXWLCP-UHFFFAOYSA-N 0.000 abstract 4
- WXTBYSIPOKXCPM-UHFFFAOYSA-N 3-acetyl-1,3-thiazolidine-4-carboxylic acid Chemical compound CC(=O)N1CSCC1C(O)=O WXTBYSIPOKXCPM-UHFFFAOYSA-N 0.000 abstract 2
- 229960001867 guaiacol Drugs 0.000 abstract 2
- 230000002349 favourable effect Effects 0.000 abstract 1
- 230000000510 mucolytic effect Effects 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22764/82A IT1190945B (it) | 1982-08-06 | 1982-08-06 | Composto ad azione broncosegretogoga,fluidificante ed antitussigena,procedimento per la sua preparazione e composizioni farmaceutiche che lo contengono |
Publications (2)
Publication Number | Publication Date |
---|---|
ES524727A0 ES524727A0 (es) | 1985-01-01 |
ES8502429A1 true ES8502429A1 (es) | 1985-01-01 |
Family
ID=11200186
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES524727A Expired ES8502429A1 (es) | 1982-08-06 | 1983-08-04 | Procedimiento para la preparacion de n-acetil-4-triazolidincarboxilato de guayacol |
Country Status (4)
Country | Link |
---|---|
JP (1) | JPS6050789B2 (de) |
DE (1) | DE3325677A1 (de) |
ES (1) | ES8502429A1 (de) |
IT (1) | IT1190945B (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63168794U (de) * | 1987-04-21 | 1988-11-02 | ||
ATE74354T1 (de) * | 1988-06-29 | 1992-04-15 | Yason Srl | N-karbethoxy-4-thiazolin-karbonsaeure, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR8266M (de) * | 1968-12-31 | 1970-10-26 | ||
FR2222087B1 (de) * | 1973-03-22 | 1976-04-09 | Ferlux |
-
1982
- 1982-08-06 IT IT22764/82A patent/IT1190945B/it active
-
1983
- 1983-07-15 DE DE19833325677 patent/DE3325677A1/de active Granted
- 1983-08-03 JP JP58142379A patent/JPS6050789B2/ja not_active Expired
- 1983-08-04 ES ES524727A patent/ES8502429A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES524727A0 (es) | 1985-01-01 |
JPS6050789B2 (ja) | 1985-11-11 |
IT8222764A0 (it) | 1982-08-06 |
DE3325677A1 (de) | 1984-02-09 |
DE3325677C2 (de) | 1988-04-07 |
IT1190945B (it) | 1988-02-24 |
JPS5944367A (ja) | 1984-03-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970303 |