ES8502436A1 - Procedimiento para la preparacion de n-(2-piridil)-(1,4-dimetil-5-(4-clorobenzoil))-2-pirrolacetamida. - Google Patents

Procedimiento para la preparacion de n-(2-piridil)-(1,4-dimetil-5-(4-clorobenzoil))-2-pirrolacetamida.

Info

Publication number
ES8502436A1
ES8502436A1 ES524706A ES524706A ES8502436A1 ES 8502436 A1 ES8502436 A1 ES 8502436A1 ES 524706 A ES524706 A ES 524706A ES 524706 A ES524706 A ES 524706A ES 8502436 A1 ES8502436 A1 ES 8502436A1
Authority
ES
Spain
Prior art keywords
analgesic
inflammatory activity
compound
pharmaceutical compositions
producing same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES524706A
Other languages
English (en)
Other versions
ES524706A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Poli Industria Chimica SpA
Original Assignee
Poli Industria Chimica SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poli Industria Chimica SpA filed Critical Poli Industria Chimica SpA
Publication of ES524706A0 publication Critical patent/ES524706A0/es
Publication of ES8502436A1 publication Critical patent/ES8502436A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE N-(2-PIRIDIL)-1,4-DIMETIL-5-(4-CLOROBENZOIL)-2-PIRROLACETAMIDA.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN EXCESO MOLAR DE 2-AMINOPIRIDINA, A UNA TEMPERATURA COMPRENDIDA ENTRE 70 Y 200JC, PARA OBTENER UN COMPUESTO DE FORMULA (I), DONDE R ES CH2 CN U OTROS.SE UTILIZA EN LA PREPARACION DE COMPUESTOS FARMACEUTICOS ANALGESICOS Y ANTIINFLAMATORIOS.
ES524706A 1982-08-04 1983-08-03 Procedimiento para la preparacion de n-(2-piridil)-(1,4-dimetil-5-(4-clorobenzoil))-2-pirrolacetamida. Expired ES8502436A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22730/82A IT1190942B (it) 1982-08-04 1982-08-04 Composto ad attivita' analgesica ed antiinfiammatoria,suo procedimento di preparazione e relative composizioni farmaceutiche

Publications (2)

Publication Number Publication Date
ES524706A0 ES524706A0 (es) 1985-01-01
ES8502436A1 true ES8502436A1 (es) 1985-01-01

Family

ID=11199756

Family Applications (1)

Application Number Title Priority Date Filing Date
ES524706A Expired ES8502436A1 (es) 1982-08-04 1983-08-03 Procedimiento para la preparacion de n-(2-piridil)-(1,4-dimetil-5-(4-clorobenzoil))-2-pirrolacetamida.

Country Status (9)

Country Link
JP (1) JPS5962586A (es)
KR (1) KR840005730A (es)
BE (1) BE897365A (es)
DE (1) DE3327080A1 (es)
ES (1) ES8502436A1 (es)
FR (1) FR2531954A1 (es)
GB (1) GB2127014B (es)
IT (1) IT1190942B (es)
PT (1) PT77025B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA848275B (en) * 1983-12-28 1985-08-28 Degussa New piridine-2-ethers or pyridine-2-thioethers having a nitrogen-containing cycloaliphatic ring
US6632823B1 (en) * 1997-12-22 2003-10-14 Merck & Co., Inc. Substituted pyridine compounds useful as modulators of acetylcholine receptors

Also Published As

Publication number Publication date
DE3327080A1 (de) 1984-02-09
PT77025A (fr) 1983-08-01
GB2127014B (en) 1985-10-02
JPS5962586A (ja) 1984-04-10
FR2531954A1 (fr) 1984-02-24
BE897365A (fr) 1983-11-14
PT77025B (fr) 1986-01-24
IT8222730A0 (it) 1982-08-04
KR840005730A (ko) 1984-11-16
GB8319437D0 (en) 1983-08-17
ES524706A0 (es) 1985-01-01
GB2127014A (en) 1984-04-04
IT1190942B (it) 1988-02-24

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20001009