ES8502133A1 - Procedimiento para la preparacion de polimeros en globulos macroporosos - Google Patents

Procedimiento para la preparacion de polimeros en globulos macroporosos

Info

Publication number
ES8502133A1
ES8502133A1 ES532831A ES532831A ES8502133A1 ES 8502133 A1 ES8502133 A1 ES 8502133A1 ES 532831 A ES532831 A ES 532831A ES 532831 A ES532831 A ES 532831A ES 8502133 A1 ES8502133 A1 ES 8502133A1
Authority
ES
Spain
Prior art keywords
preparation
macroporous polymers
beaded shape
denotes
beaded
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES532831A
Other languages
English (en)
Other versions
ES532831A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25811132&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8502133(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES532831A0 publication Critical patent/ES532831A0/es
Publication of ES8502133A1 publication Critical patent/ES8502133A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/52—Amides or imides
    • C08F20/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/087—Acrylic polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Graft Or Block Polymers (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE POLIMEROS EN GLOBULOS, A PARTIR DE MONOMEROS DE FORMULA (I), EN LA QUE X ES HIDROGENO O METILO; R ES ALQUILO C1-12 E Y ES OH O NH2, CON AL MENOS OTRO MONOMERO.LA POLIMERIZACION SE EFECTUA EN UN DISPERSANTE LIQUIDO, EN PRESENCIA DE UN INICIADOR ACTIVO POR RADICALES Y DE UN ESTABILIZADOR DE DISPERSION, TAL COMO UN COPOLIMERO A BASE DE ANHIDRIDO MALEICO Y UN VINILALQUILETER C6-30.ESTOS POLIMEROS TIENEN APLICACIONES COMO MATERIAL DE SOPORTE PARA SUSTANCIAS BIOLOGICAMENTE ACTIVAS, COMO ENZIMAS, ANTICUERPOS, ANTIGENOS Y HORMONAS.
ES532831A 1983-05-28 1984-05-25 Procedimiento para la preparacion de polimeros en globulos macroporosos Expired ES8502133A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3319506 1983-05-28
DE19843404021 DE3404021A1 (de) 1983-05-28 1984-02-06 Makroporoese perlpolymerisate, verfahren zu ihrer herstellung und ihre anwendung

Publications (2)

Publication Number Publication Date
ES532831A0 ES532831A0 (es) 1985-01-01
ES8502133A1 true ES8502133A1 (es) 1985-01-01

Family

ID=25811132

Family Applications (1)

Application Number Title Priority Date Filing Date
ES532831A Expired ES8502133A1 (es) 1983-05-28 1984-05-25 Procedimiento para la preparacion de polimeros en globulos macroporosos

Country Status (17)

Country Link
US (1) US4568706A (es)
EP (1) EP0129719B1 (es)
AT (1) ATE38678T1 (es)
AU (1) AU564409B2 (es)
BR (1) BR8402533A (es)
CA (1) CA1251890A (es)
DE (2) DE3404021A1 (es)
DK (1) DK261084A (es)
ES (1) ES8502133A1 (es)
FI (1) FI73229C (es)
GR (1) GR81579B (es)
HU (1) HUT36151A (es)
IL (1) IL71946A (es)
NO (1) NO842097L (es)
NZ (1) NZ208287A (es)
PH (1) PH22516A (es)
PT (1) PT78643B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3344912A1 (de) * 1983-12-13 1985-06-20 Hoechst Ag, 6230 Frankfurt Vernetzte polymerisate, verfahren zu ihrer herstellung und ihre anwendung
DE3413904A1 (de) * 1984-04-13 1985-10-24 Hoechst Ag, 6230 Frankfurt Polymerisate auf basis von polyvinylencarbonat und/oder polyhydroxymethylen, verfahren zu ihrer herstellung und ihre anwendung
DE3521684A1 (de) * 1985-06-18 1986-12-18 Dr. Müller-Lierheim KG, Biologische Laboratorien, 8033 Planegg Verfahren zur beschichtung von polymeren
EP0205790B1 (de) * 1985-06-18 1992-01-08 Anawa München Aktiengesellschaft Biologische Laboratorien Träger für die Kultivierung von menschlichen und/oder tierischen Zellen in einem Fermenter
US4788288A (en) * 1985-07-30 1988-11-29 Air Products And Chemicals, Inc. Self-and Hydroxyl reactive formaldehyde-free cyclic hemiamidal and hemiamide ketal crosslinking monomers
US4691026A (en) * 1985-07-30 1987-09-01 Air Products And Chemicals, Inc. Self- and hydroxyl reactive formaldehyde-free cyclic hemiamidal and hemiamide ketal crosslinking monomers
US4663410A (en) * 1985-08-06 1987-05-05 Air Products And Chemicals, Inc. Polymers of self- and hydroxyl reactive formaldehyde-free cyclic hemiamidal and hemiamide ketal crosslinking monomers
GB8521192D0 (en) * 1985-08-23 1985-10-02 Courtaulds Plc Polymeric carrier materials
DE3537259A1 (de) * 1985-10-19 1987-04-23 Hoechst Ag Copolymerisat, verfahren zu seiner herstellung und seine verwendung als enzymtraeger
US4745025A (en) * 1986-02-19 1988-05-17 Air Products And Chemicals, Inc. Nonwoven products bonded with binder emulsions of vinyl acetate/ethylene copolymers having improved solvent resistance
US4698384A (en) * 1986-02-19 1987-10-06 Air Products And Chemicals, Inc. Nonwoven binder emulsions of vinyl acetate/ethylene copolymers having improved solvent resistance
DE3629176A1 (de) * 1986-08-28 1988-03-17 Hoechst Ag Vernetzte polymerisate mit carbonatestergruppen und verfahren zu ihrer herstellung
CA2013023A1 (en) * 1989-04-17 1990-10-17 Milan F. Sojka Method of making highly adsorptive copolymers
US5100477A (en) * 1989-05-15 1992-03-31 Dow Corning Corporation Decontamination of toxic chemical agents
JPH0383914A (ja) * 1989-08-18 1991-04-09 W R Grace & Co ドラッグキャリアー
TW198064B (es) * 1990-12-24 1993-01-11 Hoechst Ag
CN1039017C (zh) * 1992-07-11 1998-07-08 南开大学 大孔聚丙烯酰胺系列树脂的合成方法
US6228340B1 (en) 1997-08-25 2001-05-08 The Regents Of The University Of California Method for the production of macroporous ceramics
DE19804518C2 (de) * 1998-02-05 2000-10-05 Roehm Gmbh Verfahren zur Herstellung von perlförmigen Mischpolymerisaten auf Acrylatbasis, danach hergestellte Trägerpolymermaterialien und deren Verwendung
US6464850B1 (en) * 1998-07-31 2002-10-15 Biowhittaker Molecular Applications, Inc. Method for producing hydrophilic monomers and uses thereof
SE0201623D0 (sv) * 2002-05-30 2002-05-30 Amersham Biosciences Ab Macroporous cross-linked polymer particles
KR101115903B1 (ko) * 2003-04-16 2012-02-13 세키스이가가쿠 고교가부시키가이샤 자성체 내포 입자 및 그의 제조 방법, 면역 측정용 입자,및 면역 측정 방법
US7276283B2 (en) * 2004-03-24 2007-10-02 Wisconsin Alumni Research Foundation Plasma-enhanced functionalization of carbon-containing substrates
US8029902B2 (en) * 2006-12-11 2011-10-04 Wisconsin Alumni Research Foundation Plasma-enhanced functionalization of substrate surfaces with quaternary ammonium and quaternary phosphonium groups
EP3993888B1 (en) * 2019-07-03 2023-11-22 Merck Patent GmbH Antibody drug conjugate purification

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3594333A (en) * 1967-07-26 1971-07-20 Univ California Formylated aromatic polymers and method of making same
DE1795235C3 (de) * 1968-08-27 1974-06-06 Pharmacia Fine Chemicals Ab, Uppsala (Schweden) Trennmittel zur Gelfiltration
DE2237316C3 (de) * 1972-07-29 1985-08-29 Roehm Gmbh, 6100 Darmstadt Verfahren zur Herstellung perlförmiger, vernetzter, wasserunlöslicher Mischpolymerisate und ihre Verwendung
JPS52137482A (en) * 1976-05-14 1977-11-16 Kyoritsu Yuki Kogyo Kenkyusho:Kk Preparation of acrylamide polymer
DE2722751C2 (de) * 1977-05-20 1990-06-21 Röhm GmbH, 6100 Darmstadt Perlpolymerisat mit einem Teilchendurchmesser von 5 bis 1000 μm und innerem Hohlraum
JPS54160300A (en) * 1978-06-08 1979-12-18 Toyo Soda Mfg Co Ltd Hydrophilic separating carrier and making method thereof
US4266610A (en) * 1978-11-28 1981-05-12 Phillips Petroleum Company Sulfonate-cosurfactant mixtures for use in hard brines during oil recovery operations

Also Published As

Publication number Publication date
ATE38678T1 (de) 1988-12-15
FI73229B (fi) 1987-05-29
FI842078A0 (fi) 1984-05-24
DK261084D0 (da) 1984-05-25
EP0129719A2 (de) 1985-01-02
DK261084A (da) 1984-11-29
CA1251890A (en) 1989-03-28
AU2877084A (en) 1984-11-29
DE3475199D1 (en) 1988-12-22
AU564409B2 (en) 1987-08-13
DE3404021A1 (de) 1984-11-29
EP0129719B1 (de) 1988-11-17
FI73229C (fi) 1987-09-10
PT78643B (de) 1986-10-20
NZ208287A (en) 1986-10-08
US4568706A (en) 1986-02-04
NO842097L (no) 1984-11-29
BR8402533A (pt) 1985-04-02
FI842078A (fi) 1984-11-29
IL71946A0 (en) 1984-09-30
IL71946A (en) 1987-11-30
ES532831A0 (es) 1985-01-01
EP0129719A3 (en) 1986-02-12
PH22516A (en) 1988-09-12
GR81579B (es) 1984-12-11
HUT36151A (en) 1985-08-28
PT78643A (de) 1984-06-01

Similar Documents

Publication Publication Date Title
ES8502133A1 (es) Procedimiento para la preparacion de polimeros en globulos macroporosos
DE3373277D1 (en) Process for preparing insoluble, only slightly expandable polymers of basic vinyl-heterocyclic compounds, and their use
TW223645B (es)
TW291486B (es)
CA1254209A (en) 3,7-DIAZA-BICYCLO-(3,3,1)-NONANE COMPOUNDS; COMPOSITIONS CONTAINING THEM; PREPARATION AND USE
MX9604374A (es) Polietilenos hidrofilicos modificados en polvo de peso molecular elevado y/o ultraelevado.
ES8503696A1 (es) Procedimiento para la preparacion de polimeros de carbonato de vinileno
AU7174487A (en) Dispersion polymers, processes for their preparation and their use
CA2029324A1 (fr) Support de catalyseur pour la polymerisation des olefines procede de fabrication du support et catalyseur obtenu a partir de ce support
ZA849504B (en) Substituted o-acylglycosylamides,a process for their preparation and their use
EP0464488A3 (en) Optically active n-alpha-fluoroacryloyl-aminoacid derivatives, their preparation, optically active polymers prepared therefrom and their use for the separation of racemates
ES8707265A1 (es) Un procedimiento para la polimerizacion
EP0415213A3 (en) Copolymers containing amino groups, process for their preparation and their use as a binder or binder-component
GB1518058A (en) Process for the preparation of a particulate material comprising titanium trichloride suitable for use in the stereospecific polymerisation of alpha-olefins
JPS6420265A (en) Immobilized product of polymer-protected metallic colloid and its production
Watanabe et al. Process for Producing Vinyl Chloride Copolymer
DE3267690D1 (en) Process for the preparation of 3-alkyl-6-methyl-beta-resorcylic-acid esters
ES479537A1 (es) Procedimiento de preparacion de esteres bencilidenicos.
EP0088522A3 (en) Novel esters or amides of azobiscarboxylic acids and their use as polymerisation initiators
JPS52128984A (en) Preparation of vinyl chloride polymers by suspension polymerization
TH33546EX (th) ผลึกโอลีฟินพอลิเมอร์และโคพอลิเมอร์ในรูปของอนุภาคทรงกลมที่มีความพรุนมาก
TW349945B (en) Substituted benzenedicarboxylic acid diguanides, process for their preparation, their use as a medicament or diagnostic
EP0394840A3 (de) 4- Hydroperoxi-2-alkensäuren und deren Ester
JPS56125396A (en) Protein an-1