ES8502093A1 - Derivados de quinolina. - Google Patents
Derivados de quinolina.Info
- Publication number
- ES8502093A1 ES8502093A1 ES522089A ES522089A ES8502093A1 ES 8502093 A1 ES8502093 A1 ES 8502093A1 ES 522089 A ES522089 A ES 522089A ES 522089 A ES522089 A ES 522089A ES 8502093 A1 ES8502093 A1 ES 8502093A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- quinoline derivatives
- formula
- cyclopropyl
- mean
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8212787 | 1982-05-04 | ||
GB838302236A GB8302236D0 (en) | 1983-01-27 | 1983-01-27 | Heterocyclic compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
ES522089A0 ES522089A0 (es) | 1984-12-16 |
ES8502093A1 true ES8502093A1 (es) | 1984-12-16 |
Family
ID=26282723
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES522089A Expired ES8502093A1 (es) | 1982-05-04 | 1983-05-04 | Derivados de quinolina. |
Country Status (13)
Country | Link |
---|---|
US (1) | US4607039A (en22) |
EP (1) | EP0093521B1 (en22) |
KR (1) | KR840004726A (en22) |
DD (1) | DD209817A5 (en22) |
DE (1) | DE3377796D1 (en22) |
DK (1) | DK199183A (en22) |
ES (1) | ES8502093A1 (en22) |
FI (1) | FI831537A7 (en22) |
GB (1) | GB8310261D0 (en22) |
GR (1) | GR78484B (en22) |
IL (1) | IL68513A0 (en22) |
NO (1) | NO831562L (en22) |
PT (1) | PT76630B (en22) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8308601D0 (en) * | 1983-03-29 | 1983-05-05 | Ici Plc | Heterocyclic compounds |
JPH064584B2 (ja) * | 1984-02-29 | 1994-01-19 | 沢井製薬株式会社 | 新規アニリド誘導体 |
US5179107A (en) * | 1990-09-07 | 1993-01-12 | Schering Corporation | Antiviral quinolinone compounds |
US5190956A (en) * | 1990-09-07 | 1993-03-02 | Schering Corporation | Certain N-substituted 3-oximino-2,4-dioxoquinolin-2,4-(1H)diones useful for treating viral infections |
EP0549729B1 (en) * | 1990-09-07 | 1997-12-17 | Schering Corporation | Antiviral compounds and antihypertensive compounds |
GB9022785D0 (en) * | 1990-10-19 | 1990-12-05 | Merck Sharp & Dohme | Therapeutic agents |
US5179093A (en) * | 1991-05-10 | 1993-01-12 | Schering Corporation | Quinoline-diones |
FR2795645B1 (fr) * | 1999-06-30 | 2001-09-21 | Union Pharma Scient Appl | Nouvelle association pharmaceutique a activite analgesique |
US6566361B2 (en) | 1999-06-30 | 2003-05-20 | Laboratories, Upsa | Azapirone pain treatment |
MY120631A (en) * | 2000-09-08 | 2005-11-30 | Union Pharma Scient Appl | Novel pharmaceutical combination having analgesic activity |
WO2007089634A2 (en) * | 2006-01-30 | 2007-08-09 | Merck & Co., Inc. | Inhibitors of fatty acid synthase (fas) |
US8680116B2 (en) * | 2009-07-22 | 2014-03-25 | Merck Sharp & Dohme Corp. | Quinolinone PDE2 inhibitors |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US16394A (en) * | 1857-01-13 | Improvement in gotton-gins | ||
DE430960C (de) * | 1924-07-11 | 1926-06-23 | J G Farbenindustrie Akt Ges | Verfahren zur Darstellung von basischen AEthern von Chinolinderivaten |
US1572768A (en) * | 1925-06-26 | 1926-02-09 | Winthrop Chem Co Inc | Pharmaceutical product |
US1860286A (en) * | 1929-05-16 | 1932-05-24 | Soc Of Chemical Ind | Basic ethers of aryl-quinolines |
GB349761A (en) * | 1929-05-16 | 1931-06-04 | Chem Ind Basel | Manufacture of aminoalkoxy-derivatives of aryl-quinolines |
US4035374A (en) * | 1973-05-03 | 1977-07-12 | Smith Kline & French Laboratories Limited | Imidazolyl alkylaminopyridone and pyridinethione compounds |
US4260764A (en) * | 1976-12-22 | 1981-04-07 | Pfizer Inc. | 9-Hydroxyoctahydrobenzo [C] quinolines and intermediates therefor |
US4343805A (en) * | 1978-12-16 | 1982-08-10 | John Wyeth & Brother Limited | Heterocyclic compounds |
US4235909A (en) * | 1979-04-19 | 1980-11-25 | Eli Lilly And Company | Octahydro-2H-pyrrolo[3,4-g]quinolines |
GR73576B (en22) * | 1980-03-01 | 1984-03-20 | Wyeth John & Brother Ltd | |
IN158970B (en22) * | 1981-06-09 | 1987-02-28 | Ici Plc |
-
1983
- 1983-04-13 EP EP83302078A patent/EP0093521B1/en not_active Expired
- 1983-04-13 DE DE8383302078T patent/DE3377796D1/de not_active Expired
- 1983-04-15 GB GB838310261A patent/GB8310261D0/en active Pending
- 1983-04-25 US US06/488,607 patent/US4607039A/en not_active Expired - Lifetime
- 1983-04-28 GR GR71238A patent/GR78484B/el unknown
- 1983-04-28 IL IL68513A patent/IL68513A0/xx unknown
- 1983-05-03 PT PT76630A patent/PT76630B/pt unknown
- 1983-05-03 DD DD25055683A patent/DD209817A5/de unknown
- 1983-05-03 NO NO831562A patent/NO831562L/no unknown
- 1983-05-04 ES ES522089A patent/ES8502093A1/es not_active Expired
- 1983-05-04 FI FI831537A patent/FI831537A7/fi not_active Application Discontinuation
- 1983-05-04 KR KR1019830001898A patent/KR840004726A/ko not_active Abandoned
- 1983-05-04 DK DK199183A patent/DK199183A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR840004726A (ko) | 1984-10-24 |
ES522089A0 (es) | 1984-12-16 |
PT76630B (en) | 1985-12-03 |
NO831562L (no) | 1983-11-07 |
FI831537L (fi) | 1983-11-05 |
DE3377796D1 (en) | 1988-09-29 |
PT76630A (en) | 1983-06-01 |
GR78484B (en22) | 1984-09-27 |
DK199183A (da) | 1983-11-05 |
EP0093521A3 (en) | 1984-08-01 |
FI831537A0 (fi) | 1983-05-04 |
US4607039A (en) | 1986-08-19 |
IL68513A0 (en) | 1983-07-31 |
FI831537A7 (fi) | 1983-11-05 |
DD209817A5 (de) | 1984-05-23 |
EP0093521B1 (en) | 1988-08-24 |
GB8310261D0 (en) | 1983-05-18 |
DK199183D0 (da) | 1983-05-04 |
EP0093521A2 (en) | 1983-11-09 |
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