ES8501980A1 - Un procedimiento para la preparacion de una vacuna contra picornavirus. - Google Patents

Un procedimiento para la preparacion de una vacuna contra picornavirus.

Info

Publication number
ES8501980A1
ES8501980A1 ES521411A ES521411A ES8501980A1 ES 8501980 A1 ES8501980 A1 ES 8501980A1 ES 521411 A ES521411 A ES 521411A ES 521411 A ES521411 A ES 521411A ES 8501980 A1 ES8501980 A1 ES 8501980A1
Authority
ES
Spain
Prior art keywords
separate
group
cys
peptide
boc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES521411A
Other languages
English (en)
Other versions
ES521411A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of ES8501980A1 publication Critical patent/ES8501980A1/es
Publication of ES521411A0 publication Critical patent/ES521411A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32111—Aphthovirus, e.g. footandmouth disease virus
    • C12N2770/32122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32611—Poliovirus
    • C12N2770/32622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UNA VACUNA CONTRA PICORNAVIRUS.COMPRENDE LAS SIGUIENTES ETAPAS: A) PROVEERSE DE UNA RESINA INSOLUBLE CONTENIENDO UNA PLURALIDAD DE GRUPOS CLOROMETILO; B) ESTERIFICAR BOC-(MEOBZL)-CYS-OH A DICHA RESINA; C) SEPARAR EL GRUPO BOC PARA OBTENER UN GRUPO AMINO LIBRE SOBRE EL RESTO CYS; D) HACER REACCIONAR LA AMINA LIBRE CON UN EXCESO DE OTRO AMINOACIDO; E) SEPARAR EL EXCESO DE ESTE OTRO AMINOACIDO; F) SEPARAR EL GRUPO BOC EN ULTIMO LUGAR PARA PROPORCIONAR UN GRUPO AMINO LIBRE; G) REPETIR LAS ETAPAS (D), (E) Y (F) HASTA QUE SE HAYA SINTETIZADO UN PEPTIDO PROTEGIDO; H) SEPARAR EL PEPTIDO PROTEGIDO SINTETIZADO DE LA RESINA Y SEPARAR LOS GRUPOS PROTECTORES PARA FORMAR UN PEPTIDO; I) PROVEERSE DE UN PORTADOR QUE CONTIENE UN GRUPO QUE REACCIONA CON EL AZUFRE DEL RESTO CYS CITADO EN PRIMER LUGAR; J) HACER REACCIONAR EL PEPTIDO CON EL PORTADOR PARA FORMAR UN CONJUGADO; Y K) DISOLVER UNA CANTIDAD EFECTIVA DEL CONJUGADO EN UN DILUYENTEFISIOLOGICAMENTE TOLERABLE PARA FORMAR UNA VACUNA.SON UTILES PARA LA DIAGNOSIS Y TRATAMIENTO DE VIRUS DE LA FAMILIA PICORNAVIRUS.
ES521411A 1982-04-14 1983-04-13 Un procedimiento para la preparacion de una vacuna contra picornavirus. Granted ES521411A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36830882A 1982-04-14 1982-04-14
US47884783A 1983-03-25 1983-03-25

Publications (2)

Publication Number Publication Date
ES8501980A1 true ES8501980A1 (es) 1984-12-16
ES521411A0 ES521411A0 (es) 1984-12-16

Family

ID=27004134

Family Applications (2)

Application Number Title Priority Date Filing Date
ES521411A Granted ES521411A0 (es) 1982-04-14 1983-04-13 Un procedimiento para la preparacion de una vacuna contra picornavirus.
ES529298A Expired ES8503952A1 (es) 1982-04-14 1984-01-31 Un procedimiento para la preparacion de una vacuna contra picornavirus

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES529298A Expired ES8503952A1 (es) 1982-04-14 1984-01-31 Un procedimiento para la preparacion de una vacuna contra picornavirus

Country Status (8)

Country Link
EP (1) EP0105346B1 (es)
CA (1) CA1253298A (es)
DE (1) DE3382459D1 (es)
ES (2) ES521411A0 (es)
FI (1) FI80601C (es)
IT (1) IT1197625B (es)
WO (1) WO1983003547A1 (es)
ZA (1) ZA832644B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA831854B (en) * 1982-03-26 1984-01-25 Biogen Nv Small peptides with the specificity of foot and mouth disease viral antigens
US4751083A (en) * 1982-05-06 1988-06-14 Massachusetts Institute Of Technology Production of neutralizing antibodies by polypeptide VP1 of enteroviruses and by oligopeptide fragments of polypeptide VP1
US5230888A (en) * 1982-05-06 1993-07-27 Massachusetts Institute Of Technology Production of neutralizing antibodies by polypeptide VP1 of enteroviruses and by oligopeptide fragments of polypeptide VP1
US4694071A (en) * 1982-10-11 1987-09-15 National Research Development Corporation Polypeptides useful in vaccination against enteroviruses
GB8301928D0 (en) * 1983-01-24 1983-02-23 Nicholson B H Process for producing polypeptides
US4708871A (en) * 1983-03-08 1987-11-24 Commonwealth Serum Laboratories Commission Antigenically active amino acid sequences
WO1984003506A1 (en) * 1983-03-08 1984-09-13 Commw Serum Lab Commission Antigenically active amino acid sequences
AU573574B2 (en) * 1983-03-08 1988-06-16 Chiron Mimotopes Pty Ltd Immunogenic deteminants of foot and mouth disease virus
EP0119153A3 (en) * 1983-03-11 1985-08-28 The Research Foundation Of State University Of New York Synthetic vaccines
FR2550094B1 (fr) * 1983-08-01 1986-03-21 Anvar Compositions de vaccins conditionnees pour la vaccination de sujets immunitairement non naifs contre un agent pathogene determine et contenant un haptene comportant lui-meme un site antigenique caracteristique dudit agent pathogene ou un oligomere de cet haptene
US4743553A (en) * 1984-07-18 1988-05-10 W. R. Grace & Co. Synthetic genes for bovine parainfluenza virus
GB8508685D0 (en) * 1985-04-03 1985-05-09 Minor P D Peptides
US4732971A (en) 1985-06-03 1988-03-22 Eli Lilly And Company Synthetic vaccines for foot and mouth disease
CN1054544C (zh) * 1993-10-21 2000-07-19 复旦大学 家畜口蹄疫病毒多肽疫苗及其制备方法
DE19638044A1 (de) * 1996-09-18 1998-03-19 Bayer Ag Immunogene Peptide von Maul- und Klauenseuchen-Viren
US6048538A (en) * 1997-10-03 2000-04-11 United Biomedical, Inc. Peptides derived from the non-structural proteins of foot and mouth disease virus as diagnostic reagents
US6107021A (en) * 1998-06-20 2000-08-22 United Biomedical, Inc. Synthetic peptide vaccines for foot-and-mouth disease
KR100531760B1 (ko) * 2003-04-28 2005-11-29 대한민국(관리부서 : 농림부 국립수의과학검역원) 구제역 바이러스의 감염여부를 진단하는 방법 및 이를구현하기 위한 진단키트
US10420832B2 (en) 2012-11-16 2019-09-24 United Biomedical, Inc. Synthetic peptide-based emergency vaccine against foot and mouth disease (FMD)
CN109799344A (zh) * 2018-12-07 2019-05-24 中国农业科学院兰州兽医研究所 一种基于Asia I型口蹄疫病毒样颗粒的竞争ELISA抗体检测试剂盒

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4140763A (en) * 1976-09-08 1979-02-20 The United States Of America As Represented By The Secretary Of Agriculture Vaccine for foot and mouth disease
GB2079288B (en) * 1980-05-12 1984-05-16 Biogen Nv Dna sequences recombinat dna molecules and processes for producing polypeptides with the specificity of foot and mouth disease viral antigens
FI83662C (fi) * 1980-07-17 1991-08-12 Scripps Clinic Res Diagnostik antikropp och foerfarande foer dess framstaellning.
GB2103622B (en) * 1981-06-16 1986-01-15 Genentech Inc Production of foot and mouth disease vaccine from microbially expressed antigens
ZA831854B (en) * 1982-03-26 1984-01-25 Biogen Nv Small peptides with the specificity of foot and mouth disease viral antigens
DE3374170D1 (en) * 1982-05-06 1987-12-03 Massachusetts Inst Technology Production of enterovirus neutralizing antibodies from vp1
EP0105481A1 (en) * 1982-09-30 1984-04-18 The Wellcome Foundation Limited Novel antigens and vaccines containing them
DE3381494D1 (de) * 1982-11-30 1990-05-31 Pasteur Institut Immunogen-lage des poliovirus enthaltende peptide und dns enthaltend nukleotidfragmente die fuer diese peptide kodieren.
EP0268693B1 (en) * 1986-11-20 1989-10-18 Komori Printing Machinery Co., Ltd. Sheet conveyance table for sheet press

Also Published As

Publication number Publication date
FI834590A (fi) 1983-12-14
ES529298A0 (es) 1985-04-16
ES8503952A1 (es) 1985-04-16
EP0105346B1 (en) 1991-11-13
FI834590A0 (fi) 1983-12-14
EP0105346A1 (en) 1984-04-18
CA1253298A (en) 1989-04-25
FI80601B (fi) 1990-03-30
FI80601C (fi) 1990-07-10
DE3382459D1 (de) 1991-12-19
ZA832644B (en) 1983-12-28
WO1983003547A1 (en) 1983-10-27
EP0105346A4 (en) 1987-11-23
IT1197625B (it) 1988-12-06
ES521411A0 (es) 1984-12-16
IT8348094A0 (it) 1983-04-13

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303