ES8501231A1 - Un procedimiento para la preparacion de formulaciones granuladas con antibioticos estabilizados. - Google Patents
Un procedimiento para la preparacion de formulaciones granuladas con antibioticos estabilizados.Info
- Publication number
- ES8501231A1 ES8501231A1 ES521194A ES521194A ES8501231A1 ES 8501231 A1 ES8501231 A1 ES 8501231A1 ES 521194 A ES521194 A ES 521194A ES 521194 A ES521194 A ES 521194A ES 8501231 A1 ES8501231 A1 ES 8501231A1
- Authority
- ES
- Spain
- Prior art keywords
- stabilization
- food supplements
- drugs
- unstable drugs
- hydroxide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940079593 drug Drugs 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 3
- 235000015872 dietary supplement Nutrition 0.000 title abstract 2
- 230000006641 stabilisation Effects 0.000 title abstract 2
- 238000011105 stabilization Methods 0.000 title abstract 2
- -1 e.g. Substances 0.000 abstract 2
- 239000005660 Abamectin Substances 0.000 abstract 1
- HMSYAPGFKGSXAJ-PAHGNTJYSA-N Mocimycin Chemical compound C(/[C@H]1O[C@H]([C@H]([C@H]1O)O)[C@H](C)[C@H](OC)C(/C)=C/C=C/CNC(=O)[C@@H](CC)[C@]1(O)[C@@H]([C@H](O)C(C)(C)[C@H](\C=C\C=C/C)O1)O)=C\C=C\C=C(/C)C(=O)C1=C(O)NC=CC1=O HMSYAPGFKGSXAJ-PAHGNTJYSA-N 0.000 abstract 1
- 229920000615 alginic acid Polymers 0.000 abstract 1
- 239000000783 alginic acid Substances 0.000 abstract 1
- 229960001126 alginic acid Drugs 0.000 abstract 1
- 235000010443 alginic acid Nutrition 0.000 abstract 1
- 150000004781 alginic acids Chemical class 0.000 abstract 1
- ASOJLQIBBYOFDE-HCHBIZCOSA-N chembl2106443 Chemical compound C(/[C@H]1O[C@H]([C@H]([C@H]1O)O)[C@H](C)[C@H](OC)C(/C)=C/C=C/CNC(=O)[C@@H](CC)[C@]1(O)[C@@H]([C@H](O[C@H]2[C@@H]([C@H](OC)[C@H](O[C@H]3[C@@H]([C@H](O)[C@@H](OC)[C@H](C)O3)OC)[C@@H](C)O2)O)C(C)(C)[C@H](\C=C\C=C\C)O1)O)=C\C=C\C=C(/C)C(=O)C1=C(O)C=CN(C)C1=O ASOJLQIBBYOFDE-HCHBIZCOSA-N 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 229950003445 efrotomycin Drugs 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000003349 gelling agent Substances 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 238000005469 granulation Methods 0.000 abstract 1
- 230000003179 granulation Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 1
- 150000002680 magnesium Chemical class 0.000 abstract 1
- VTHJTEIRLNZDEV-UHFFFAOYSA-L magnesium dihydroxide Chemical compound [OH-].[OH-].[Mg+2] VTHJTEIRLNZDEV-UHFFFAOYSA-L 0.000 abstract 1
- 229910001862 magnesium hydroxide Inorganic materials 0.000 abstract 1
- 239000000347 magnesium hydroxide Substances 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- FXWHFKOXMBTCMP-WMEDONTMSA-N milbemycin Natural products COC1C2OCC3=C/C=C/C(C)CC(=CCC4CC(CC5(O4)OC(C)C(C)C(OC(=O)C(C)CC(C)C)C5O)OC(=O)C(C=C1C)C23O)C FXWHFKOXMBTCMP-WMEDONTMSA-N 0.000 abstract 1
- ZLBGSRMUSVULIE-GSMJGMFJSA-N milbemycin A3 Chemical class O1[C@H](C)[C@@H](C)CC[C@@]11O[C@H](C\C=C(C)\C[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 ZLBGSRMUSVULIE-GSMJGMFJSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229950008095 mocimycin Drugs 0.000 abstract 1
- HMSYAPGFKGSXAJ-KNHRXMRASA-N mocimycin Natural products C([C@H]1O[C@H]([C@H]([C@H]1O)O)[C@H](C)[C@H](OC)C(C)=CC=CCNC(=O)[C@@H](CC)[C@]1(O)[C@@H]([C@H](O)C(C)(C)[C@H](C=CC=CC)O1)O)=CC=CC=C(C)C(=O)C1=C(O)NC=CC1=O HMSYAPGFKGSXAJ-KNHRXMRASA-N 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 150000004804 polysaccharides Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/195—Antibiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/24—Compounds of alkaline earth metals, e.g. magnesium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Fodder In General (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE FORMULACIONES GRANULADAS CON ANTIBIOTICOS ESTABILIZADOS, QUE SE INCORPORAN A LOS ALIMENTOS O A LOS COMPONENTES ALIMENTICIOS.COMPRENDE LAS SIGUIENTES OPERACIONES: PRIMERA, SE FORMA UN AGLOMERADO COMPUESTO POR 0,1 A 70 PARTES EN PESO DE UN COMPUESTOS ANTIBIOTICO SELECCIONADO ENTRE EFROTOMICINA, IVERMECTINA, MILBEMICINA, TILOSINA Y SIMILARES, POR 10 A 80 PARTES EN PESO DE UN AGENTE GELIFICANTE POLISACARIDO, Y POR 10 A 80 PARTES EN PESO DE UNA SAL METALICA; SEGUNDA, A DICHO AGLOMERADO SE LE AN/ADE ENTRE 0,05 A 80 PARTES EN VOLUMEN DE UN DISOLVENTE, PARA FORMAR UNA MASA HUMEDA; Y POR ULTIMO, SE TAMIZA DICHA MASA HUMEDA Y SE SECA A UNA TEMPERATURA ADECUADA, HASTA CONSEGUIR LOS GRANULOS DE TAMAN/O ADECUADO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36541882A | 1982-04-05 | 1982-04-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8501231A1 true ES8501231A1 (es) | 1984-12-01 |
| ES521194A0 ES521194A0 (es) | 1984-12-01 |
Family
ID=23438838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES521194A Granted ES521194A0 (es) | 1982-04-05 | 1983-03-30 | Un procedimiento para la preparacion de formulaciones granuladas con antibioticos estabilizados. |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0091767B1 (es) |
| JP (1) | JPS58190357A (es) |
| KR (1) | KR910000743B1 (es) |
| AT (1) | ATE50492T1 (es) |
| AU (1) | AU555304B2 (es) |
| CA (1) | CA1213217A (es) |
| DE (1) | DE3381235D1 (es) |
| DK (1) | DK163343C (es) |
| ES (1) | ES521194A0 (es) |
| GR (1) | GR78150B (es) |
| HK (1) | HK25091A (es) |
| IE (1) | IE56276B1 (es) |
| IL (1) | IL68282A0 (es) |
| NZ (1) | NZ203684A (es) |
| PT (1) | PT76448B (es) |
| ZA (1) | ZA832400B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2575008B2 (ja) * | 1986-03-31 | 1997-01-22 | 日本農薬株式会社 | 動物用医薬品組成物 |
| US5152995A (en) * | 1986-12-18 | 1992-10-06 | Syntex (U.S.A.) Inc. | Stable antibiotic ester feed compositions |
| DK172608B1 (da) * | 1986-12-18 | 1999-02-22 | Syntex Inc | Antibiotisk foderblanding med forøget lagerstabilitet, dyrefoderforblandingspræparat med forøget lagerstabilitet til behand |
| SI8710674B (sl) * | 1987-04-14 | 1998-06-30 | Pliva | Postopek za pripravo 10,11,12,13-tetrahidro derivatov tilozina |
| JPH02124894A (ja) * | 1988-11-01 | 1990-05-14 | Sanwa Kagaku Kenkyusho Co Ltd | フィチン酸安定化組成物 |
| SG42865A1 (en) * | 1991-07-24 | 1997-10-17 | Enzacor Pty Ltd | Therapeutic compositions and methods |
| MX9308001A (es) * | 1992-12-21 | 1994-08-31 | Lilly Co Eli | Premezcla para piensos de animales que contiene tilosina y procedimiento para su obtencion. |
| GB9306106D0 (en) * | 1993-03-24 | 1993-05-12 | Norbrook Lab Ltd | Sustained release veterinary composition |
| FI980902A (fi) | 1998-04-23 | 1999-10-24 | Orion Yhtymae Oyj | Levosimendaanin stabiileja koostumuksia |
| FI980901A (fi) | 1998-04-23 | 1999-10-24 | Orion Yhtymae Oyj | Levosimendaania säädellysti vapauttavia oraalisia koostumuksia |
| DE10056345A1 (de) | 2000-11-14 | 2002-05-29 | Rettenmaier & Soehne Gmbh & Co | Futtermittel |
| GB0230034D0 (en) * | 2002-12-23 | 2003-01-29 | Biochemie Gmbh | Organic compounds |
| US7671034B2 (en) * | 2003-12-19 | 2010-03-02 | Merial Limited | Stabilized formulation of ivermectin feed premix with an extended shelf life |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3150042A (en) * | 1963-03-15 | 1964-09-22 | Upjohn Co | Treating coccidiosis with lincomycin |
| US3627885A (en) * | 1968-07-18 | 1971-12-14 | Rit Rech Ind Therapeut | Stabilized antibiotic compositions for animal feeding |
| JPS4856577A (es) * | 1971-11-22 | 1973-08-08 | ||
| US4042685A (en) * | 1974-05-15 | 1977-08-16 | Walton John Smith | Milk of magnesia |
| US4048268A (en) * | 1975-02-19 | 1977-09-13 | Eli Lilly And Company | Stabilization method |
| US4087556A (en) * | 1976-12-22 | 1978-05-02 | Chemische Industrie Randstad, N.V. | Folic acid animal feed materials and processes |
| JPS58175449A (ja) * | 1982-04-02 | 1983-10-14 | Nippon Soda Co Ltd | 反すう動物用飼料添加組成物 |
-
1983
- 1983-03-24 NZ NZ203684A patent/NZ203684A/en unknown
- 1983-03-24 AU AU12764/83A patent/AU555304B2/en not_active Ceased
- 1983-03-24 PT PT76448A patent/PT76448B/pt not_active IP Right Cessation
- 1983-03-30 ES ES521194A patent/ES521194A0/es active Granted
- 1983-03-30 CA CA000424955A patent/CA1213217A/en not_active Expired
- 1983-03-30 DK DK146283A patent/DK163343C/da not_active IP Right Cessation
- 1983-03-31 IE IE737/83A patent/IE56276B1/en not_active IP Right Cessation
- 1983-04-01 IL IL68282A patent/IL68282A0/xx not_active IP Right Cessation
- 1983-04-04 KR KR1019830001398A patent/KR910000743B1/ko not_active IP Right Cessation
- 1983-04-04 GR GR70975A patent/GR78150B/el unknown
- 1983-04-05 DE DE8383301890T patent/DE3381235D1/de not_active Expired - Lifetime
- 1983-04-05 EP EP83301890A patent/EP0091767B1/en not_active Expired - Lifetime
- 1983-04-05 AT AT83301890T patent/ATE50492T1/de not_active IP Right Cessation
- 1983-04-05 JP JP58058831A patent/JPS58190357A/ja active Granted
- 1983-04-05 ZA ZA832400A patent/ZA832400B/xx unknown
-
1991
- 1991-04-04 HK HK250/91A patent/HK25091A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GR78150B (es) | 1984-09-26 |
| HK25091A (en) | 1991-04-12 |
| JPH0427816B2 (es) | 1992-05-12 |
| EP0091767A3 (en) | 1986-01-15 |
| DK146283A (da) | 1983-10-06 |
| KR910000743B1 (ko) | 1991-02-06 |
| DK163343C (da) | 1992-07-20 |
| IL68282A0 (en) | 1983-07-31 |
| AU555304B2 (en) | 1986-09-18 |
| JPS58190357A (ja) | 1983-11-07 |
| DK163343B (da) | 1992-02-24 |
| AU1276483A (en) | 1983-10-13 |
| ATE50492T1 (de) | 1990-03-15 |
| IE56276B1 (en) | 1991-06-05 |
| DE3381235D1 (de) | 1990-04-05 |
| CA1213217A (en) | 1986-10-28 |
| PT76448A (en) | 1983-04-01 |
| DK146283D0 (da) | 1983-03-30 |
| ZA832400B (en) | 1984-11-28 |
| IE830737L (en) | 1983-10-05 |
| KR840004347A (ko) | 1984-10-15 |
| EP0091767B1 (en) | 1990-02-28 |
| NZ203684A (en) | 1986-06-11 |
| PT76448B (en) | 1986-03-20 |
| EP0091767A2 (en) | 1983-10-19 |
| ES521194A0 (es) | 1984-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970519 |