ES8500892A1 - Un procedimiento para la preparacion de un nuevo derivado n-acil-peptidico. - Google Patents

Un procedimiento para la preparacion de un nuevo derivado n-acil-peptidico.

Info

Publication number
ES8500892A1
ES8500892A1 ES518771A ES518771A ES8500892A1 ES 8500892 A1 ES8500892 A1 ES 8500892A1 ES 518771 A ES518771 A ES 518771A ES 518771 A ES518771 A ES 518771A ES 8500892 A1 ES8500892 A1 ES 8500892A1
Authority
ES
Spain
Prior art keywords
alkyl
carboxy
hydrogen
amino
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES518771A
Other languages
English (en)
Other versions
ES518771A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of ES8500892A1 publication Critical patent/ES8500892A1/es
Publication of ES518771A0 publication Critical patent/ES518771A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06052—Val-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UN DERIVADO N-ACILPEPTIDICO, DE FORMULA (I), EN LA QUE R ES HIDROGENO, ALCANOILOXI O ALQUENOILOXI; R ES ALQUILO O ALQUENILO; R Y R SON CADA UNO DE ELLOS HIDROGENO, ALQUILO INFERIOR O ARALQUILO INFERIOR; R ES HIDROGENO, AMINOALQUILO INFERIOR O HIDROXIALQUILO INFERIOR; R ES CARBOXI O SULFOALQUILO INFERIOR; A, A Y A SON CADA UNO DE ELLOS UN ENLACE O ALQUILENO INFERIOR; Y M Y N SON CADA UNO DE ELLOS 0 O 1, Y SUS SALES FARMACEUTICAMENTE ACEPTABLES.DE APLICACION COMO AGENTES TERAPEUTICOS EN EL TRATAMIENTO DE ENFERMEDADES INMUNOCOMPLEJAS Y AUTOINMUNITARIAS.
ES518771A 1982-01-05 1983-01-04 Un procedimiento para la preparacion de un nuevo derivado n-acil-peptidico. Granted ES518771A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8200212 1982-01-05
GB8215910 1982-06-01

Publications (2)

Publication Number Publication Date
ES8500892A1 true ES8500892A1 (es) 1984-03-01
ES518771A0 ES518771A0 (es) 1984-03-01

Family

ID=26281659

Family Applications (1)

Application Number Title Priority Date Filing Date
ES518771A Granted ES518771A0 (es) 1982-01-05 1983-01-04 Un procedimiento para la preparacion de un nuevo derivado n-acil-peptidico.

Country Status (11)

Country Link
US (1) US4643990A (es)
EP (1) EP0085255B1 (es)
KR (1) KR840003235A (es)
AT (1) ATE22087T1 (es)
AU (1) AU9173582A (es)
DE (1) DE3273256D1 (es)
DK (1) DK579682A (es)
ES (1) ES518771A0 (es)
FI (1) FI824453L (es)
GR (1) GR77060B (es)
NO (1) NO830011L (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU560285B2 (en) * 1982-07-19 1987-04-02 Imperial Chemical Industries Plc Heterocyclyl carbonyl sulphonamides
EP0136879A3 (en) * 1983-09-30 1987-01-07 Yamanouchi Pharmaceutical Co., Ltd. Fatty acid derivatives and processes of producing them
DE3423582A1 (de) * 1984-06-27 1986-01-09 Bayer Ag, 5090 Leverkusen Substituierte 5-acylamino-1-phenylpyrazole
DE3700173A1 (de) * 1987-01-05 1988-07-14 Hoechst Ag Verfahren zur herstellung von lipophilen aminosaeurederivaten sowie lipophile aminosaeurederivate
FR2611205B1 (fr) * 1987-02-20 1990-03-02 Serbio Dipeptides, procede de preparation et utilisation dans le dosage de proteases
US5464825A (en) * 1991-03-14 1995-11-07 Cornell Research Foundation, Inc. Raising glutathione equivalent levels using N-acyl glutathione monoesters
EP0697882A4 (en) * 1993-05-03 1999-04-07 Cornell Res Foundation Inc USE OF GLUTATHION DIESTERS
US5627210A (en) * 1995-02-06 1997-05-06 Chiron Corporation Branched combinatorial libraries
WO2001035982A1 (fr) * 1999-11-12 2001-05-25 Fujimoto Brothers Co., Ltd. Compositions medicinales anti-inflammatoires
WO2005053727A2 (en) * 2003-11-29 2005-06-16 Sangstat Medical Corporation Pharmaceutical compositions for bioactive peptide agents

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL279057A (es) * 1900-01-01
NL109134C (es) * 1900-01-01
FR2907E (fr) * 1903-03-09 1904-07-12 Brunet Loiseau Freres Soc Interrupteur-vibreur pour bobine d'induction, en vue de l'allumage des moteurs
FR4629E (fr) * 1904-04-21 1905-09-02 Jean Victorin Poplawski Générateur de vapeur à mèche
FR7648E (fr) * 1906-02-26 1907-09-17 Georges Clesse Dispositif de changement de vitesse et de renversement de marche pour voitures automobiles
NL299197A (es) * 1957-07-11
JPS4211925Y1 (es) * 1966-02-09 1967-07-05
DE1593858A1 (de) * 1967-03-02 1970-10-29 Hoechst Ag Verfahren zur Herstellung tyrosinhaltiger Peptide und deren Derivaten
JPS468685Y1 (es) * 1967-08-02 1971-03-27
JPS46164Y1 (es) * 1967-09-05 1971-01-07
US3893992A (en) * 1970-11-19 1975-07-08 Rohm & Haas N-acylated peptides of amino aromatic sulfonic acids and their derivatives
FR2340983A1 (fr) * 1976-02-10 1977-09-09 Ugine Kuhlmann Activateurs pour percomposes
LU78804A1 (de) * 1977-12-30 1979-07-20 Byk Gulden Lomberg Chem Fab N-substituierte w-aminoalkanoyl-w-aminoalkansaeuren,ihre verwendung und verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
US4205069A (en) * 1978-09-29 1980-05-27 American Home Products Corporation Dipeptide narcotic antagonists
EP0011283B1 (en) * 1978-11-14 1982-07-28 Fujisawa Pharmaceutical Co., Ltd. New lactyl tetrapeptide, processes for preparation thereof and pharmaceutical compositions containing it
US4311640A (en) * 1978-11-14 1982-01-19 Fujisawa Pharmaceutical Co., Ltd. Peptide, process for preparation thereof and use thereof
FR2460288A1 (fr) * 1979-06-29 1981-01-23 Rhone Poulenc Ind Nouveaux dipeptides, leur preparation et les medicaments qui les contiennent
US4436726A (en) * 1980-12-15 1984-03-13 Fujisawa Pharmaceutical Co., Ltd. N-Acylpeptide compound, processes for the preparation thereof and the pharmaceutical compositions

Also Published As

Publication number Publication date
EP0085255A2 (en) 1983-08-10
AU9173582A (en) 1983-07-14
US4643990A (en) 1987-02-17
ES518771A0 (es) 1984-03-01
DK579682A (da) 1983-07-06
FI824453L (fi) 1983-07-06
FI824453A0 (fi) 1982-12-27
ATE22087T1 (de) 1986-09-15
NO830011L (no) 1983-07-06
EP0085255A3 (en) 1984-08-01
EP0085255B1 (en) 1986-09-10
DE3273256D1 (en) 1986-10-16
GR77060B (es) 1984-09-05
KR840003235A (ko) 1984-08-20

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