ES8406491A1 - Procedimiento para la obtencion de nuevas cefaloesporinas - Google Patents

Procedimiento para la obtencion de nuevas cefaloesporinas

Info

Publication number
ES8406491A1
ES8406491A1 ES526674A ES526674A ES8406491A1 ES 8406491 A1 ES8406491 A1 ES 8406491A1 ES 526674 A ES526674 A ES 526674A ES 526674 A ES526674 A ES 526674A ES 8406491 A1 ES8406491 A1 ES 8406491A1
Authority
ES
Spain
Prior art keywords
preparation
cephalosporin derivatives
alkyl
phenyl
alkylcarbamoyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES526674A
Other languages
English (en)
Other versions
ES526674A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES8406491A1 publication Critical patent/ES8406491A1/es
Publication of ES526674A0 publication Critical patent/ES526674A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE NUEVAS CEFALOSPORINAS.CONSISTE EN OBTENER COMPUESTOS DE FORMULA (I) EN LOS QUE R SIGNIFICA C1-C6 U OTROS, Y R Y R, QUE PUEDEN SER IGUALES O DIFERENTES, SIGNIFICAN H, C1, C6 U OTRO. A UN ACIDO CARBOXILICO DE FORMULA (II), DONDE R TIENE EL SIGNIFICADO ANTERIOR, SE HACE REACCIONAR EN UN DISOLVENTE ORGANICO POLAR A TEMPERATURAS BAJAS CON UN COMPUESTO DE X-SO2-R; LA SOLUCION ASI OBTENIDA SE AGREGA A UNA DISOLUCION ACUOSA DE CEFALOESPORANATO DE FORMULA (III) O SU SAL, EN PRESENCIA DE 1-4 EQUIVALENTES DE UNA BASE.SE EMPLEA COMO MEDICAMENTOEN LA TERAPIA ANTIBACTERIANA.
ES526674A 1982-10-23 1983-10-21 Procedimiento para la obtencion de nuevas cefaloesporinas Granted ES526674A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823239365 DE3239365A1 (de) 1982-10-23 1982-10-23 Neue cephalosporine und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
ES8406491A1 true ES8406491A1 (es) 1984-07-01
ES526674A0 ES526674A0 (es) 1984-07-01

Family

ID=6176491

Family Applications (1)

Application Number Title Priority Date Filing Date
ES526674A Granted ES526674A0 (es) 1982-10-23 1983-10-21 Procedimiento para la obtencion de nuevas cefaloesporinas

Country Status (19)

Country Link
US (1) US4489076A (es)
EP (1) EP0107138B1 (es)
JP (1) JPS5993086A (es)
KR (1) KR840006487A (es)
AT (1) ATE29498T1 (es)
AU (1) AU556826B2 (es)
CA (1) CA1208206A (es)
DE (2) DE3239365A1 (es)
DK (1) DK486183A (es)
ES (1) ES526674A0 (es)
FI (1) FI73689C (es)
GR (1) GR79682B (es)
HU (1) HU189763B (es)
IL (1) IL70012A (es)
NO (1) NO833644L (es)
NZ (1) NZ206017A (es)
PH (3) PH20918A (es)
PT (1) PT77501B (es)
ZA (1) ZA837850B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3300593A1 (de) * 1983-01-11 1984-07-12 Bayer Ag, 5090 Leverkusen Neue cephalosporine und verfahren zu ihrer herstellung
DE3343208A1 (de) * 1983-11-30 1985-06-05 Bayer Ag, 5090 Leverkusen Neue cephalosporine und verfahren zu ihrer herstellung
DE3418376A1 (de) * 1984-05-17 1985-11-21 Bayer Ag, 5090 Leverkusen Zwischenprodukte sowie verfahren zur herstellung von zwischenprodukten fuer die synthese von cephalosporinen
DE3419012A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel oder wachstumsfoerderer in der tieraufzucht oder als antioxidantien
JP2501785B2 (ja) * 1984-07-09 1996-05-29 明治製菓株式会社 新規セフアロスポリン系化合物
AT397963B (de) * 1985-03-29 1994-08-25 Shionogi & Co Verfahren zur herstellung von neuen 7 beta-(2-(2- amino-4-thiazolyl)-alkenoylamimo)-3-cephem-4- carbonsäureestern
AU580855B2 (en) * 1985-03-29 1989-02-02 Shionogi & Co., Ltd. Alkeneamidocephalosporin esters
JP4554395B2 (ja) 2005-02-17 2010-09-29 浜松ホトニクス株式会社 光源装置
JP4589142B2 (ja) 2005-02-17 2010-12-01 浜松ホトニクス株式会社 光源装置

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4970990A (es) * 1973-09-29 1974-07-09
NZ176206A (en) * 1973-12-25 1978-03-06 Takeda Chemical Industries Ltd Cephalosporins
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
US4148997A (en) * 1977-11-07 1979-04-10 Yeda Research And Development Co., Ltd. 7-[Sulfomethyl)phenyl]acetamidocephalosporin derivatives
GB2058791B (en) * 1978-05-26 1982-11-24 Glaxo Group Ltd Cephalosporin antibiotics
IT1148888B (it) * 1980-07-15 1986-12-03 Schiena Ricerche Di Composti antibiotici
DE3037997A1 (de) * 1980-10-08 1982-05-13 Bayer Ag (beta) -lactamantibiotika, verfahren zu deren herstellung sowie sie enthaltende mittel
DE3145727A1 (de) * 1981-11-19 1983-05-26 Bayer Ag, 5090 Leverkusen Zwischenprodukte, verfahren zu deren herstellung und verfahren zur herstellung von cephalosporinen

Also Published As

Publication number Publication date
HU189763B (en) 1986-07-28
ZA837850B (en) 1984-06-27
FI833846A0 (fi) 1983-10-20
NZ206017A (en) 1985-11-08
HUT34210A (en) 1985-02-28
US4489076A (en) 1984-12-18
FI73689B (fi) 1987-07-31
ATE29498T1 (de) 1987-09-15
IL70012A (en) 1987-09-16
PT77501A (en) 1983-11-01
AU2044783A (en) 1984-05-03
JPS5993086A (ja) 1984-05-29
NO833644L (no) 1984-04-24
FI833846A (fi) 1984-04-24
ES526674A0 (es) 1984-07-01
EP0107138A2 (de) 1984-05-02
KR840006487A (ko) 1984-11-30
PH20908A (en) 1987-05-27
GR79682B (es) 1984-10-31
DK486183A (da) 1984-04-24
AU556826B2 (en) 1986-11-20
CA1208206A (en) 1986-07-22
DE3373476D1 (en) 1987-10-15
DE3239365A1 (de) 1984-04-26
DK486183D0 (da) 1983-10-21
EP0107138B1 (de) 1987-09-09
PH20918A (en) 1987-05-28
FI73689C (fi) 1987-11-09
PT77501B (en) 1986-02-12
IL70012A0 (en) 1984-01-31
EP0107138A3 (en) 1985-05-15
PH20665A (en) 1987-03-23

Similar Documents

Publication Publication Date Title
ES8603497A1 (es) Procedimiento para preparar derivados de cefalosporina
ES8406491A1 (es) Procedimiento para la obtencion de nuevas cefaloesporinas
AU572916B2 (en) Cephalosporin derivatives
DE3269780D1 (en) Cephalosporin derivatives and process for their preparation
GB2068958B (en) 7-(2-amino-4-thiazolyl) acetamido cephalosporins
PT83712A (de) Cephalosporinderivate und verfahren zu ihrer herstellung
GB2068959B (en) 7-(2-amino-4-thiazolyl) acetamido cephalosporins
ES8404362A1 (es) Un procedimiento para preparar nuevos compuestos de cefem.
IL63892A (en) 7-(2-(aminothiazol-4yl)acetamido)cephalosporin derivatives,processes for producing the same and pharmaceutical compositions comprising them