ES8404852A1 - Procedimiento para preparar derivados de acidos isoquinolein-4-carboxilicos - Google Patents
Procedimiento para preparar derivados de acidos isoquinolein-4-carboxilicosInfo
- Publication number
- ES8404852A1 ES8404852A1 ES525441A ES525441A ES8404852A1 ES 8404852 A1 ES8404852 A1 ES 8404852A1 ES 525441 A ES525441 A ES 525441A ES 525441 A ES525441 A ES 525441A ES 8404852 A1 ES8404852 A1 ES 8404852A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- isoquinoline derivatives
- isoquinoline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 125000002183 isoquinolinyl group Chemical class C1(=NC=CC2=CC=CC=C12)* 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000003288 anthiarrhythmic effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- MCVMLYSLPCECGO-UHFFFAOYSA-N isoquinoline-4-carboxylic acid Chemical class C1=CC=C2C(C(=O)O)=CN=CC2=C1 MCVMLYSLPCECGO-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823233424 DE3233424A1 (de) | 1982-09-09 | 1982-09-09 | Isochinolinderivate, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8404852A1 true ES8404852A1 (es) | 1984-05-16 |
| ES525441A0 ES525441A0 (es) | 1984-05-16 |
Family
ID=6172780
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES525441A Granted ES525441A0 (es) | 1982-09-09 | 1983-09-07 | Procedimiento para preparar derivados de acidos isoquinolein-4-carboxilicos |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4673682A (enEXAMPLES) |
| EP (1) | EP0105210B1 (enEXAMPLES) |
| JP (1) | JPS5967270A (enEXAMPLES) |
| KR (1) | KR840006206A (enEXAMPLES) |
| AT (1) | ATE25679T1 (enEXAMPLES) |
| AU (1) | AU1891683A (enEXAMPLES) |
| CA (1) | CA1211445A (enEXAMPLES) |
| DE (2) | DE3233424A1 (enEXAMPLES) |
| DK (1) | DK408083A (enEXAMPLES) |
| ES (1) | ES525441A0 (enEXAMPLES) |
| FI (1) | FI833200A7 (enEXAMPLES) |
| GR (1) | GR79382B (enEXAMPLES) |
| HU (1) | HU191094B (enEXAMPLES) |
| IL (1) | IL69683A0 (enEXAMPLES) |
| NO (1) | NO833217L (enEXAMPLES) |
| NZ (1) | NZ205513A (enEXAMPLES) |
| PH (1) | PH18186A (enEXAMPLES) |
| PT (1) | PT77309B (enEXAMPLES) |
| ZA (1) | ZA836663B (enEXAMPLES) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4956371A (en) * | 1989-09-19 | 1990-09-11 | Euroceltique, S.A. | Substituted isoquinolines and methods of using same |
| PT590455E (pt) * | 1992-09-28 | 2001-04-30 | Hoechst Ag | 1(2h)-isoquinolinas substituidas anti-arritmicas e cardioprotectoras processo para a sua preparacao medicamento contendo estes compostos e sua utilizacao para a preparacao de um medicamento para o combate de falhas cardiacas |
| US5552412A (en) * | 1995-01-09 | 1996-09-03 | Pfizer Inc | 5-substitued-6-cyclic-5,6,7,8-tetrahydronaphthalen2-ol compounds which are useful for treating osteoporosis |
| US7323475B2 (en) | 2003-06-06 | 2008-01-29 | Fibrogen, Inc. | Nitrogen-containing heteroaryl compounds and methods of use thereof |
| JP5161793B2 (ja) | 2006-01-27 | 2013-03-13 | フィブロジェン， インコーポレイテッド | 低酸素症誘導因子（ｈｉｆ）を安定化するシアノイソキノリン化合物 |
| BRPI0710527B8 (pt) * | 2006-04-04 | 2021-05-25 | Fibrogen Inc | compostos de pirrolo- e tiazolo-piridina e composição farmacêutica que os compreende |
| JP5649584B2 (ja) | 2008-11-14 | 2015-01-07 | フィブロジェン インコーポレイテッド | Ｈｉｆヒドロキシラーゼ阻害剤としてのチオクロメン誘導体 |
| SG11201405574UA (en) | 2012-03-09 | 2014-10-30 | Fibrogen Inc | 4 -hydroxy- isoquinoline compounds as hif hydroxylase inhibitors |
| US8883823B2 (en) | 2012-07-16 | 2014-11-11 | Fibrogen, Inc. | Crystalline forms of a prolyl hydroxylase inhibitor |
| US9115085B2 (en) | 2012-07-16 | 2015-08-25 | Fibrogen, Inc. | Crystalline forms of a prolyl hydroxylase inhibitor |
| HUE034409T2 (en) | 2012-07-16 | 2018-02-28 | Fibrogen Inc | Process for the preparation of isoquinoline compounds |
| SG11201505748UA (en) | 2013-01-24 | 2015-08-28 | Fibrogen Inc | Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2054482B1 (enEXAMPLES) * | 1969-07-11 | 1973-06-08 | Anvar | |
| FR2424270A1 (fr) * | 1978-04-24 | 1979-11-23 | Rhone Poulenc Ind | Nouveaux derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent |
| DE2818423A1 (de) * | 1978-04-27 | 1979-11-08 | Hoechst Ag | Neue isochinolinderivate und verfahren zu ihrer herstellung |
-
1982
- 1982-09-09 DE DE19823233424 patent/DE3233424A1/de not_active Withdrawn
-
1983
- 1983-09-03 EP EP83108697A patent/EP0105210B1/de not_active Expired
- 1983-09-03 AT AT83108697T patent/ATE25679T1/de not_active IP Right Cessation
- 1983-09-03 DE DE8383108697T patent/DE3369983D1/de not_active Expired
- 1983-09-07 IL IL69683A patent/IL69683A0/xx unknown
- 1983-09-07 PH PH29505A patent/PH18186A/en unknown
- 1983-09-07 NZ NZ205513A patent/NZ205513A/en unknown
- 1983-09-07 GR GR72399A patent/GR79382B/el unknown
- 1983-09-07 KR KR1019830004199A patent/KR840006206A/ko not_active Withdrawn
- 1983-09-07 FI FI833200A patent/FI833200A7/fi not_active Application Discontinuation
- 1983-09-07 ES ES525441A patent/ES525441A0/es active Granted
- 1983-09-07 US US06/530,000 patent/US4673682A/en not_active Expired - Fee Related
- 1983-09-08 HU HU833134A patent/HU191094B/hu unknown
- 1983-09-08 CA CA000436316A patent/CA1211445A/en not_active Expired
- 1983-09-08 PT PT77309A patent/PT77309B/pt unknown
- 1983-09-08 NO NO833217A patent/NO833217L/no unknown
- 1983-09-08 ZA ZA836663A patent/ZA836663B/xx unknown
- 1983-09-08 AU AU18916/83A patent/AU1891683A/en not_active Abandoned
- 1983-09-08 DK DK408083A patent/DK408083A/da not_active Application Discontinuation
- 1983-09-08 JP JP58164274A patent/JPS5967270A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NZ205513A (en) | 1986-05-09 |
| DK408083A (da) | 1984-03-10 |
| ATE25679T1 (de) | 1987-03-15 |
| PT77309A (de) | 1983-10-01 |
| PT77309B (de) | 1986-04-18 |
| US4673682A (en) | 1987-06-16 |
| JPS5967270A (ja) | 1984-04-16 |
| HU191094B (en) | 1987-01-28 |
| CA1211445A (en) | 1986-09-16 |
| DE3369983D1 (en) | 1987-04-09 |
| GR79382B (enEXAMPLES) | 1984-10-22 |
| EP0105210A3 (en) | 1984-10-10 |
| FI833200A7 (fi) | 1984-03-10 |
| PH18186A (en) | 1985-04-12 |
| DE3233424A1 (de) | 1984-03-15 |
| EP0105210A2 (de) | 1984-04-11 |
| FI833200A0 (fi) | 1983-09-07 |
| ZA836663B (en) | 1984-04-25 |
| NO833217L (no) | 1984-03-12 |
| IL69683A0 (en) | 1983-12-30 |
| AU1891683A (en) | 1984-03-15 |
| EP0105210B1 (de) | 1987-03-04 |
| KR840006206A (ko) | 1984-11-22 |
| ES525441A0 (es) | 1984-05-16 |
| DK408083D0 (da) | 1983-09-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0500143A3 (en) | Pharmaceutical composition comprising an aminoglycoside phosphate | |
| ZA926328B (en) | Naphthylethylureas and naphthylethylthioureas process for the preparation thereof and pharmaceutical compositions containing them. | |
| EP0163599A3 (en) | Pyrimidopyrimidine derivatives, processes for producing them, pharmaceutical compositions containing them and their use as anti-allergic agents | |
| IL69095A (en) | 9-(2-hydroxyethoxymethyl)-guanine derivatives,their preparation and pharmaceutical compositions containing them | |
| IL57648A (en) | 2-substituted-5,9-dimethyl-2'-hydroxy-6,7-benzomorphanes,their preparation and pharmaceutical compositions containing them | |
| ES8801277A1 (es) | Procedimiento para preparar (1,2,4) triazolo (1,5-c) quinazolinas | |
| IL96636A0 (en) | Piperidine derivatives and pharmaceutical compositions containing them | |
| ES8402261A1 (es) | Procedimiento para la obtencion de nuevos derivados de omega-ciano-1,omega difenil-aza-alcano. | |
| DE3167320D1 (en) | Novel uracil derivatives, process for preparing the same and a pharmaceutical composition containing the same | |
| ES8102561A1 (es) | Procedimiento de preparacion de los aril-1 arilsulfonil-4 a amino-propoxi-3 1h pirazoles | |
| ES8202784A1 (es) | Un procedimiento para la preparacion de derivados de aminas secundarias. | |
| IL108571A0 (en) | Derivatives of quinolonecarboxylic acid and naphthyrdionecarboxylic acid, their preparation and pharmaceutical compositions containing them | |
| ES8403494A1 (es) | "un procedimiento para la preparacion de derivados de s-adenosilmetionina". | |
| ES8401960A1 (es) | Procedimiento para la preparacion de imidazolilfenil-tetrahidropiridazinas. | |
| ES8404852A1 (es) | Procedimiento para preparar derivados de acidos isoquinolein-4-carboxilicos | |
| ES8403910A1 (es) | Procedimiento para la preparacion de nitratos de amino-deso-xi-1.4;3.6-dianhidro-hexito,asi como de sus sales de adicionacida farmacologicamente inocuas | |
| ES8401944A1 (es) | Procedimiento para la preparacion de derivados de acido salicilico. | |
| TW252979B (enEXAMPLES) | ||
| ES8801633A1 (es) | Procedimiento para preparar nuevos derivados de 3-piridil-metilnaftilo | |
| IL71068A0 (en) | N-arylpiperazine derivative,its preparation and pharmaceutical compositions containing it | |
| ES8201575A1 (es) | Procedimiento de obtencion de nuevos 2-aminoetanoles | |
| IL67400A0 (en) | 3,7alpha-diazacyclohepta(j,k)fluorene derivatives,their preparation and pharmaceutical compositions containing them | |
| ATE23528T1 (de) | +/- 2-((3,4-methylenedioxy)phenethyl)-5-((3carboxamido-4-hydroxy)-alpha-hydroxybenzyl)pyrrolidine, pharmazeutische zusammenstellungen die sie enthalten, verfahren zur herstellung und deren zwischenprodukte. | |
| ZA948515B (en) | Cyclised analogues of fatty acid metabolites,a process for their preparation and pharmaceutical compositions containing them |