ES8404788A2 - Perfeccionamientos en la patente de invencion n 511.472 por procedimiento para la obtencion del 4-hidroxi-2-metil-n-(2-piridil)-2h-1,2-benzotiazina-3-carboxamida-1,1-dioxido. - Google Patents

Perfeccionamientos en la patente de invencion n 511.472 por procedimiento para la obtencion del 4-hidroxi-2-metil-n-(2-piridil)-2h-1,2-benzotiazina-3-carboxamida-1,1-dioxido.

Info

Publication number
ES8404788A2
ES8404788A2 ES518908A ES518908A ES8404788A2 ES 8404788 A2 ES8404788 A2 ES 8404788A2 ES 518908 A ES518908 A ES 518908A ES 518908 A ES518908 A ES 518908A ES 8404788 A2 ES8404788 A2 ES 8404788A2
Authority
ES
Spain
Prior art keywords
alkyl
benzothiazine
methyl
halo
prepn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES518908A
Other languages
English (en)
Other versions
ES518908A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medichem SA
Original Assignee
Medichem SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medichem SA filed Critical Medichem SA
Priority to ES518908A priority Critical patent/ES518908A0/es
Priority to CA000422926A priority patent/CA1197244A/en
Priority to GR70707A priority patent/GR78072B/el
Priority to US06/472,831 priority patent/US4478996A/en
Priority to PT76352A priority patent/PT76352B/pt
Priority to DE19833308377 priority patent/DE3308377A1/de
Priority to GB08307008A priority patent/GB2118544B/en
Priority to KR1019830001097A priority patent/KR900008812B1/ko
Priority to NL8301004A priority patent/NL8301004A/nl
Priority to FR8305460A priority patent/FR2525219B1/fr
Priority to AT0131483A priority patent/AT380241B/de
Publication of ES8404788A2 publication Critical patent/ES8404788A2/es
Publication of ES518908A0 publication Critical patent/ES518908A0/es
Granted legal-status Critical Current

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  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DEL 4-HIDROXI-2-METIL-N-( 2-PIRIDIL)-2H-1,2-BENZOTIAZINA-3-CARBOXAMIDA-1,1,-DIOXIDO (CERTIFICADO DE ADICION DE LA PATENTE NUM. 511.472).CONSISTE EN TRATAR EL 1,1-DIOXIDO DE 4-HIDROXI-2-METIL-2H-1,2-BENZOTIAZINA-3-CARBOXILATO DE ALQUILO EN EL QUE EL RADICAL ALQUILO ESTA CONSTITUIDO POR UNO, TRES, CUATRO, CINCO O SEIS ATOMOS DE CARBONO, CON EL BROMURO DE 2-AMINOPIRIDIL-MAGNESIO EN EL SENO DE UN DISOLVENTE INERTE A LA REACCION Y A UNA TEMPERATURA COMPRENDIDA ENTRE 0 Y 130 GRADOS, HASTA QUE LA REACCION SEA SUSTANCIALMENTE COMPLETA. POSTERIORMENTE SE SOMETE A HIDROLISIS ACIDA EL CUERPOINTERMEDIO OBTENIDO, SEGUIDA DE RECRISTALIZACION.DE APLICACION EN MEDICINA POR SUS PROPIEDADES ANALGESICAS Y ANTIINFLAMATORIAS.
ES518908A 1982-04-16 1983-01-11 Perfeccionamientos en la patente de invencion n 511.472 por procedimiento para la obtencion del 4-hidroxi-2-metil-n-(2-piridil)-2h-1,2-benzotiazina-3-carboxamida-1,1-dioxido. Granted ES518908A0 (es)

Priority Applications (11)

Application Number Priority Date Filing Date Title
ES518908A ES518908A0 (es) 1983-01-11 1983-01-11 Perfeccionamientos en la patente de invencion n 511.472 por procedimiento para la obtencion del 4-hidroxi-2-metil-n-(2-piridil)-2h-1,2-benzotiazina-3-carboxamida-1,1-dioxido.
CA000422926A CA1197244A (en) 1982-04-16 1983-03-04 Process for the preparation of 4-hydroxy-2-methyl-2h- 1,2-benzothiazine-3-carboxamide-1,1-dioxides
GR70707A GR78072B (es) 1982-04-16 1983-03-07
US06/472,831 US4478996A (en) 1982-04-16 1983-03-07 Process for the preparation of 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxides
PT76352A PT76352B (en) 1982-04-16 1983-03-07 Process for preparing 4-hidroxy-2-methyl-2h-1,2-benzothiazine-3-carboxamide-1,1-dioxide
DE19833308377 DE3308377A1 (de) 1982-04-16 1983-03-09 Verfahren zur herstellung von 4-hydroxy-2-methyl-2h-1,2-benzothiazin-3-carboxamind-1,1-dioxiden
GB08307008A GB2118544B (en) 1982-04-16 1983-03-14 A process for the preparation of 4-hydroxy-2-methyl-2h-1,2--benzothiazine-3-carboxamide-1,1-dioxides
KR1019830001097A KR900008812B1 (ko) 1982-04-16 1983-03-18 4-하이드록시-2-메틸-2h-1,2-벤조티아진-3-카복스아마이드-1,1-디옥사이드의 제조방법
NL8301004A NL8301004A (nl) 1982-04-16 1983-03-21 Werkwijze voor de bereiding van 4-hydroxy-2- methyl-2h-1,2-benzothiazine-3-carboxamide-1,1-dioxiden.
FR8305460A FR2525219B1 (fr) 1982-04-16 1983-04-01 Procede pour la preparation de 4-hydroxy-2-methyl-2h-1,2-benzothiazine-3-carboxamide-1-1-dioxydes
AT0131483A AT380241B (de) 1982-04-16 1983-04-13 Verfahren zur herstellung von 4-hydroxy-2-methyl-2h-1,2-benzothiazin-3-carbox mid-1,1-dioxiden

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES518908A ES518908A0 (es) 1983-01-11 1983-01-11 Perfeccionamientos en la patente de invencion n 511.472 por procedimiento para la obtencion del 4-hidroxi-2-metil-n-(2-piridil)-2h-1,2-benzotiazina-3-carboxamida-1,1-dioxido.

Publications (2)

Publication Number Publication Date
ES8404788A2 true ES8404788A2 (es) 1984-06-01
ES518908A0 ES518908A0 (es) 1984-06-01

Family

ID=8485205

Family Applications (1)

Application Number Title Priority Date Filing Date
ES518908A Granted ES518908A0 (es) 1982-04-16 1983-01-11 Perfeccionamientos en la patente de invencion n 511.472 por procedimiento para la obtencion del 4-hidroxi-2-metil-n-(2-piridil)-2h-1,2-benzotiazina-3-carboxamida-1,1-dioxido.

Country Status (1)

Country Link
ES (1) ES518908A0 (es)

Also Published As

Publication number Publication date
ES518908A0 (es) 1984-06-01

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