ES8403447A1 - Procedimiento para preparar un nuevo derivado de la benzhidrilsulfiniletilamina. - Google Patents
Procedimiento para preparar un nuevo derivado de la benzhidrilsulfiniletilamina.Info
- Publication number
- ES8403447A1 ES8403447A1 ES522983A ES522983A ES8403447A1 ES 8403447 A1 ES8403447 A1 ES 8403447A1 ES 522983 A ES522983 A ES 522983A ES 522983 A ES522983 A ES 522983A ES 8403447 A1 ES8403447 A1 ES 8403447A1
- Authority
- ES
- Spain
- Prior art keywords
- benzhydrylsulfinyl
- therapy
- preparation
- ethyl amines
- amines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 Benzhydrylsulfinyl ethyl Chemical group 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- SHMYXVVITSBKCM-UHFFFAOYSA-N 2-benzhydrylsulfinylethanamine Chemical class C=1C=CC=CC=1C([S+]([O-])CCN)C1=CC=CC=C1 SHMYXVVITSBKCM-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/28—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Anesthesiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR UN DERIVADO DE LA BENZHIDRILSULFINILETILAMINA, DE FORMULA GENERAL (I), EN LA QUE R ES UN GRUPO ALQUILO DE C1-C4, Y SUS SALES DE ADICION DE ACIDO.CONSISTE EN HACER REACCIONAR EN AGUA, EN PRESENCIA DE UNA BASE PARTICULARMENTE SELECCIONADA ENTRE NAOH Y KOH, EL DIFENILMETANOTIOL, DE FORMULA (C6H5)2 CH-SH, CON UNA 2-BROMOETILAMINA DE FORMULA: BR-CH2CH2-NHR, EN LA QUE R TIENE EL SIGNIFICADO YA INDICADO, PARA OBTENER UNA BENZHIDRILTIOETILAMINA, DE FORMULA (II), Y A CONTINUACION SE SOMETE EL COMPUESTO DE FORMULA (II) ASI OBTENIDO A UNA REACCION DE OXIDACION EN ACIDOACETICO POR MEDIO DE H2O2.DE APLICACION EN LA PREPARACION DE COMPOSICIONES TERAPEUTICAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8209804A FR2528040A1 (fr) | 1982-06-04 | 1982-06-04 | Benzhydrylsulfinylethylamines, procede de preparation et utilisation en therapeutique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8403447A1 true ES8403447A1 (es) | 1984-03-16 |
| ES522983A0 ES522983A0 (es) | 1984-03-16 |
Family
ID=9274665
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES522983A Granted ES522983A0 (es) | 1982-06-04 | 1983-06-03 | Procedimiento para preparar un nuevo derivado de la benzhidrilsulfiniletilamina. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0097546B1 (es) |
| JP (1) | JPS591457A (es) |
| AT (1) | ATE15796T1 (es) |
| CA (1) | CA1215393A (es) |
| DE (1) | DE3360881D1 (es) |
| DK (1) | DK160090C (es) |
| ES (1) | ES522983A0 (es) |
| FR (1) | FR2528040A1 (es) |
| IE (1) | IE54987B1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4518637B2 (ja) * | 2000-07-07 | 2010-08-04 | 住友精化株式会社 | ２−（メチルスルホニル）エチルアミンの製造方法 |
| US7314875B2 (en) | 2004-04-13 | 2008-01-01 | Cephalon, Inc. | Tricyclic aromatic and bis-phenyl sulfinyl derivatives |
| US9862679B2 (en) | 2013-03-08 | 2018-01-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Office Of Technology Transfer, National Institutes Of Health | Potent and selective inhibitors of monoamine transporters; method of making; and use thereof |
| WO2019094856A1 (en) | 2017-11-13 | 2019-05-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Atypical inhibitors of monoamine transporters; method of making; and use thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1520812A (en) * | 1975-10-02 | 1978-08-09 | Lafon Labor | Benzhydrylsulphinyl derivatives |
-
1982
- 1982-06-04 FR FR8209804A patent/FR2528040A1/fr active Granted
-
1983
- 1983-05-26 EP EP83401048A patent/EP0097546B1/fr not_active Expired
- 1983-05-26 DE DE8383401048T patent/DE3360881D1/de not_active Expired
- 1983-05-26 IE IE1249/83A patent/IE54987B1/en not_active IP Right Cessation
- 1983-05-26 AT AT83401048T patent/ATE15796T1/de not_active IP Right Cessation
- 1983-05-31 CA CA000429260A patent/CA1215393A/en not_active Expired
- 1983-06-03 DK DK253483A patent/DK160090C/da not_active IP Right Cessation
- 1983-06-03 ES ES522983A patent/ES522983A0/es active Granted
- 1983-06-04 JP JP58098796A patent/JPS591457A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE3360881D1 (en) | 1985-10-31 |
| ATE15796T1 (de) | 1985-10-15 |
| EP0097546A1 (fr) | 1984-01-04 |
| CA1215393A (en) | 1986-12-16 |
| DK160090C (da) | 1991-06-24 |
| IE54987B1 (en) | 1990-04-11 |
| ES522983A0 (es) | 1984-03-16 |
| IE831249L (en) | 1983-12-04 |
| EP0097546B1 (fr) | 1985-09-25 |
| JPS591457A (ja) | 1984-01-06 |
| DK160090B (da) | 1991-01-28 |
| DK253483D0 (da) | 1983-06-03 |
| FR2528040A1 (fr) | 1983-12-09 |
| DK253483A (da) | 1983-12-05 |
| FR2528040B1 (es) | 1984-12-28 |
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