ES8401983A1 - Procedimiento para la preparacion de inmunoglobulina administrable por via intravenosa. - Google Patents

Procedimiento para la preparacion de inmunoglobulina administrable por via intravenosa.

Info

Publication number
ES8401983A1
ES8401983A1 ES518181A ES518181A ES8401983A1 ES 8401983 A1 ES8401983 A1 ES 8401983A1 ES 518181 A ES518181 A ES 518181A ES 518181 A ES518181 A ES 518181A ES 8401983 A1 ES8401983 A1 ES 8401983A1
Authority
ES
Spain
Prior art keywords
preparation
human
intravenously administrable
human immunoglobuline
immunoglobuline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES518181A
Other languages
English (en)
Other versions
ES518181A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cilag GmbH International
Original Assignee
Schweiz Serum und Impfinstitut und Institut zur Erforschung der Infektionskrankheiten
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4194125&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8401983(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schweiz Serum und Impfinstitut und Institut zur Erforschung der Infektionskrankheiten filed Critical Schweiz Serum und Impfinstitut und Institut zur Erforschung der Infektionskrankheiten
Publication of ES518181A0 publication Critical patent/ES518181A0/es
Publication of ES8401983A1 publication Critical patent/ES8401983A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE INMUNOGLOBULINA ADMINISTRABLE POR VIA INTRAVENOSA, INALTERADA QUIMICAMENTE Y NO DEGRADADA ENZIMATICAMENTE, PARA REFORZAR LA DEFENSA INMUNE DEL ORGANISMO HUMANO.COMPRENDE LAS SIGUIENTES OPERACIONES: PRIMERA, UNA INMUNOGLOBULINA OBTENIDA A PARTIR DE PLASMA HUMANO O DE PLACENTAS HUMANAS SE FIJA PRIMERAMENTE A UN INTERCAMBIADOR DE IONES; SEGUNDA, A PARTIR DE DICHA INMUNOGLOBULINA SE ELUYE SELECTIVAMENTE LA INMUNOGLOBULINA MONOMERA Y ESTA SE ESTABILIZA POR TRATAMIENTO CON UN ACIDO MUY DEBIL O POR ADICION DE UN POLIGLICOLY DE UN AZUCAR O DE UN POLIOL, SIENDO INDISPENSABLE LA ADICION DE UN POLIGLICOL Y DE UN AZUCAR; Y POR ULTIMO, SE ELIMINAN LOS ULTIMOS RESTOS DE ACTIVIDAD ANTICOMPLEMENTARIA POR ADSORCION EN OXIDO DE ALUMINIO.
ES518181A 1982-02-08 1982-12-14 Procedimiento para la preparacion de inmunoglobulina administrable por via intravenosa. Expired ES8401983A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH74182 1982-02-08

Publications (2)

Publication Number Publication Date
ES518181A0 ES518181A0 (es) 1984-01-16
ES8401983A1 true ES8401983A1 (es) 1984-01-16

Family

ID=4194125

Family Applications (1)

Application Number Title Priority Date Filing Date
ES518181A Expired ES8401983A1 (es) 1982-02-08 1982-12-14 Procedimiento para la preparacion de inmunoglobulina administrable por via intravenosa.

Country Status (12)

Country Link
EP (1) EP0085747B2 (es)
JP (1) JPS58159424A (es)
AR (1) AR229486A1 (es)
AT (1) ATE19735T1 (es)
AU (1) AU554817B2 (es)
DE (1) DE3271181D1 (es)
DK (1) DK157367C (es)
ES (1) ES8401983A1 (es)
FI (1) FI73597C (es)
PH (1) PH20924A (es)
PT (1) PT75979B (es)
ZA (1) ZA828687B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58180433A (ja) * 1982-04-16 1983-10-21 Fujirebio Inc 免疫グロブリンから抗補体作用物質の除去法
US4439421A (en) * 1982-08-30 1984-03-27 Baxter Travenol Laboratories, Inc. Stabilized gamma globulin concentrate
EP0116571B2 (en) * 1982-08-30 1997-10-29 BAXTER INTERNATIONAL INC. (a Delaware corporation) Method for making gamma globulin-containing compositions
JP2691708B2 (ja) * 1984-09-26 1997-12-17 住友製薬株式会社 ヒトモノクローナル抗体およびその製法
GB8519848D0 (en) * 1985-08-07 1985-09-11 Schweiz Rotes Kreuz Treatment of chronic inflammatory disease
DE3641115A1 (de) * 1986-12-02 1988-06-16 Lentia Gmbh Verfahren zur herstellung eines intravenoes anwendbaren und in fluessiger form stabilen immunglobulins
AT389817B (de) * 1987-01-22 1990-02-12 Schwab & Co Ges Mbh Verfahren zur herstellung eines in fluessiger form stabilen immunglobulins zur intravenoesen anwendung
ES2051830T3 (es) * 1987-11-27 1994-07-01 Akzo Nv Solucion acuosa estable de anticuerpos.
DE3927111C3 (de) * 1989-08-17 1994-09-01 Biotest Pharma Gmbh Verfahren zur Herstellung nicht modifizierter intravenös verabreichbarer IgM- und/oderIgA-haltiger Immunglobulinpräparate
JPH0778025B2 (ja) * 1990-03-20 1995-08-23 日本赤十字社 免疫グロブリンｇの製造方法
US5256771A (en) * 1990-04-03 1993-10-26 Miles Inc. Heat treatment of IgM-containing immunoglobulins to eliminate non-specific complement activation
DE59309332D1 (de) * 1993-12-27 1999-03-04 Rotkreuzstiftung Zentratrallab Verfahren zur Herstellung eines Konzentrates von Anti-D-Immunoglobulin G und pharmazeutische Zusammensetzung, die dieses enthält
TWI391399B (zh) 2005-05-25 2013-04-01 Hoffmann La Roche 測定溶離多肽之鹽濃度之方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2500076C3 (de) * 1975-01-02 1982-11-18 SCHURA Blutderivate GmbH & Co KG, 4150 Krefeld Verfahren zur Gewinnung von intravenös-verträglichen Gammaglobulinen
DE2527064C3 (de) * 1975-06-18 1979-11-15 Biotest-Serum-Institut Gmbh, 6000 Frankfurt Verfahren zur Herstellung eines intravenösen Nativ-Human-Immunglobulin-Präparates mit natürlicher Halbwertszeit und gegenüber dem Ausgangsmaterial unveränderten Antikörperaktivität
US4126605A (en) * 1975-12-29 1978-11-21 Plasmesco Ag Process of improving the compatibility of gamma globulins
US4124576A (en) * 1976-12-03 1978-11-07 Coval M L Method of producing intravenously injectable gamma globulin
JPS5822085B2 (ja) * 1977-07-19 1983-05-06 株式会社ミドリ十字 静注用ガンマ・グロブリン製剤
DE2837168A1 (de) * 1978-08-25 1980-03-06 Blutspendedienst Dt Rote Kreuz Verfahren zur herstellung einer fuer die intravenoese anwendung geeigneten immunglobulinloesung
JPS5625114A (en) * 1979-08-07 1981-03-10 Green Cross Corp:The Preparation of human gamma globulin
US4374763A (en) * 1979-09-17 1983-02-22 Morishita Pharmaceutical Co., Ltd. Method for producing gamma-globulin for use in intravenous administration and method for producing a pharmaceutical preparation thereof
JPS58180433A (ja) * 1982-04-16 1983-10-21 Fujirebio Inc 免疫グロブリンから抗補体作用物質の除去法

Also Published As

Publication number Publication date
DK26583D0 (da) 1983-01-24
FI73597B (fi) 1987-07-31
JPS58159424A (ja) 1983-09-21
EP0085747A2 (de) 1983-08-17
FI73597C (fi) 1987-11-09
ATE19735T1 (de) 1986-05-15
PH20924A (en) 1987-06-05
DK157367B (da) 1989-12-27
ZA828687B (en) 1983-09-28
JPH0365327B2 (es) 1991-10-11
DE3271181D1 (en) 1986-06-19
FI824283L (fi) 1983-08-09
DK26583A (da) 1983-08-09
ES518181A0 (es) 1984-01-16
EP0085747B1 (de) 1986-05-14
AU9132882A (en) 1983-08-18
EP0085747B2 (de) 1990-05-30
PT75979B (de) 1985-10-04
DK157367C (da) 1990-05-21
AR229486A1 (es) 1983-08-31
AU554817B2 (en) 1986-09-04
FI824283A0 (fi) 1982-12-14
PT75979A (de) 1983-01-01
EP0085747A3 (en) 1984-09-05

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