FI861150A - Monoklonala antikroppar mot metallkelat. - Google Patents

Monoklonala antikroppar mot metallkelat. Download PDF

Info

Publication number
FI861150A
FI861150A FI861150A FI861150A FI861150A FI 861150 A FI861150 A FI 861150A FI 861150 A FI861150 A FI 861150A FI 861150 A FI861150 A FI 861150A FI 861150 A FI861150 A FI 861150A
Authority
FI
Finland
Prior art keywords
metal coils
complex
monoclonal
antibody
mot
Prior art date
Application number
FI861150A
Other languages
English (en)
Other versions
FI861150A0 (fi
FI87532B (fi
FI87532C (fi
Inventor
Claude F Meares
Gary S David
Original Assignee
Hybritech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hybritech Inc filed Critical Hybritech Inc
Publication of FI861150A0 publication Critical patent/FI861150A0/fi
Publication of FI861150A publication Critical patent/FI861150A/fi
Publication of FI87532B publication Critical patent/FI87532B/fi
Application granted granted Critical
Publication of FI87532C publication Critical patent/FI87532C/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y10S436/813—Cancer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Glass Compositions (AREA)
  • Electric Double-Layer Capacitors Or The Like (AREA)
  • Cereal-Derived Products (AREA)
FI861150A 1984-08-31 1986-03-19 Monoklonala antikroppar mot metallkelat FI87532C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/646,602 US4722892A (en) 1984-08-31 1984-08-31 Monoclonal antibodies against metal chelates
US64660284 1984-08-31
PCT/US1985/001603 WO1986001407A1 (en) 1984-08-31 1985-08-23 Monoclonal antibodies against metal chelates
US8501603 1985-08-23

Publications (4)

Publication Number Publication Date
FI861150A0 FI861150A0 (fi) 1986-03-19
FI861150A true FI861150A (fi) 1986-03-19
FI87532B FI87532B (fi) 1992-10-15
FI87532C FI87532C (fi) 1993-01-25

Family

ID=24593709

Family Applications (1)

Application Number Title Priority Date Filing Date
FI861150A FI87532C (fi) 1984-08-31 1986-03-19 Monoklonala antikroppar mot metallkelat

Country Status (14)

Country Link
US (1) US4722892A (fi)
EP (1) EP0193561B1 (fi)
JP (1) JPS62500120A (fi)
CN (1) CN85107873A (fi)
AT (1) ATE68353T1 (fi)
AU (1) AU587993B2 (fi)
BR (1) BR8506896A (fi)
CA (1) CA1275952C (fi)
DE (1) DE3584443D1 (fi)
DK (1) DK157086A (fi)
FI (1) FI87532C (fi)
IL (1) IL76183A0 (fi)
NO (1) NO174136C (fi)
WO (1) WO1986001407A1 (fi)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4518356A (en) * 1983-09-30 1985-05-21 Dentsply Research & Development Corp. Utrasonic dental file and method of determining failure resistant lengths thereof
GB8408193D0 (en) * 1984-03-30 1984-05-10 Cambridge Patent Dev Antibodies
GB2161165A (en) * 1984-06-12 1986-01-08 Cambridge Patent Dev Secondary antibodies
GB8530829D0 (en) * 1985-12-13 1986-01-22 Syngene International Nv Monoclonal antibodies
FR2604092B1 (fr) * 1986-09-19 1990-04-13 Immunotech Sa Immunoreactifs destines a cibler les cellules animales pour leur visualisation ou leur destruction in vivo
US5053226A (en) * 1987-07-15 1991-10-01 Board Of Regents, The University Of Texas System Monoclonal antibodies binding platinum complexes
AU609939B2 (en) * 1988-02-03 1991-05-09 University Of Melbourne, The Tumour imaging
IL89490A0 (en) * 1988-11-17 1989-09-10 Hybritech Inc Chimeric antibodies directed against metal chelates
US5639624A (en) * 1989-03-14 1997-06-17 Board Of Regents Of The University Of Nebraska Monoclonal antibodies specific for metallic cations and method therefor
US5972656A (en) * 1989-03-14 1999-10-26 Bionebraska, Inc. Mercury binding polypeptides and nucleotides coding therefore
WO1990010709A2 (en) * 1989-03-14 1990-09-20 Board Of Regents Of The University Of Nebraska Monoclonal antibodies for metallic cations on small molecules
WO1990012109A1 (en) * 1989-03-30 1990-10-18 Board Of Regents, The University Of Texas System Monoclonal antibodies binding platinum complexes
DE3920358A1 (de) * 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
US5112951A (en) * 1989-07-28 1992-05-12 Hybritech Incorporated Separation of anti-metal chelate antibodies
DE4007079A1 (de) * 1990-03-07 1991-09-12 Behringwerke Ag Monoklonale antikoerper gegen komplexierte und nicht komplexierte komplexbildner zur entfernung von schwermetallen aus waessrigen loesungen
IL97459A0 (en) * 1990-03-09 1992-06-21 Hybritech Inc Trifunctional antibody-like compounds as a combined diagnostic and therapeutic agent
US5273743A (en) * 1990-03-09 1993-12-28 Hybritech Incorporated Trifunctional antibody-like compounds as a combined diagnostic and therapeutic agent
US5091542A (en) * 1990-03-09 1992-02-25 Hybritech Incorporated Tris-maleimido compounds as intermediates in trifunctional antibody synthesis
GB9015683D0 (en) * 1990-07-17 1990-09-05 Amersham Int Plc Testing for metal ions
EP0640216B1 (en) * 1991-03-20 2002-10-02 Marconi Optical Components Limited Separation method
AU2400692A (en) * 1991-07-19 1993-02-23 Hybritech Incorporated Trifunctional compounds having specificity for multi-drug resistant cells
IT1257908B (it) * 1992-07-10 1996-02-16 Mini Ricerca Scient Tecnolog Proccedimento per la produzione di ittrio-90 e generatore di ittrio-90
ZA938243B (en) * 1992-11-12 1995-05-04 Hybritech Inc Altered affinity polypeptides of metal chelate binding antibodies
US5532136A (en) * 1993-06-22 1996-07-02 Bionebraska, Inc. Monoclonal antibody assay and kit for detecting metal cations in body fluids
US5459040A (en) * 1993-11-22 1995-10-17 The Regents Of The University Of California Enzyme amplified, complex linked, competitive and non-competitive assays for the detection of metal ions
US5476939A (en) * 1993-12-30 1995-12-19 Abbott Laboratories Certain pyridyl and isoquinolyl carbinolamine derivatives
CA2190727C (en) * 1994-05-19 2006-07-18 Sudhakar Kasina Aromatic amine substituted bridged nitrogen and sulfur donor atom ligands for imaging
US6111079A (en) * 1995-06-05 2000-08-29 Bionebraska, Inc. Lead binding polypeptides and nucleotides coding therefore
US5962291A (en) * 1996-04-19 1999-10-05 The Regents Of The University Of Colorado Metal dependent catalytic antibodies and method for producing the same
US6005083A (en) * 1997-03-28 1999-12-21 Neorx Corporation Bridged aromatic substituted amine ligands with donor atoms
US6190923B1 (en) 1997-09-05 2001-02-20 David K. Johnson Diethylenetriamine-N,N′,N″-triacetic acid derivatives
EP1103552A4 (en) * 1998-08-07 2003-01-15 Takeda Chemical Industries Ltd BENZOTHIEPINE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE
IL127621A (en) * 1998-12-17 2002-05-23 Yissum Res Dev Co Method for measuring non-bound metal in serum and biological fluids
MY133346A (en) * 1999-03-01 2007-11-30 Biogen Inc Kit for radiolabeling ligands with yttrium-90
US20020102208A1 (en) * 1999-03-01 2002-08-01 Paul Chinn Radiolabeling kit and binding assay
EP1218413A4 (en) * 1999-09-27 2005-06-15 Univ California IRREVERSIBLE BINDING ANTIBODY MANIPULATIONS
US7118745B1 (en) 1999-09-27 2006-10-10 The Regents Of The University Of California Engineering antibodies that bind irreversibly
US20030049800A1 (en) * 2000-12-15 2003-03-13 Saravis Calvin A. Compositions and methods for producing antibodies to low molecular weight analytes
US6686202B2 (en) * 2001-08-08 2004-02-03 Placer Dome, Inc. Methods for detecting and extracting gold
KR20040058229A (ko) * 2001-10-22 2004-07-03 더 스크립스 리서치 인스티튜트 항체 표적화 화합물
WO2003034995A2 (en) * 2001-10-22 2003-05-01 The Scripps Research Institute Integrin targeting compounds
US7820787B2 (en) * 2003-01-23 2010-10-26 The Regents Of The University Of California Multi-functional antibodies
JP4722534B2 (ja) * 2005-04-12 2011-07-13 財団法人電力中央研究所 抗３価クロムモノクローナル抗体およびその使用方法
US20130344619A1 (en) 2012-06-21 2013-12-26 Lightship Medical Limited Glucose sensor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4401764A (en) * 1980-02-07 1983-08-30 Technicon Instruments Corporation Immunoassays employing labeled reagent and a conjugate having two binding sites
US4474893A (en) * 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
US4522918A (en) * 1981-12-15 1985-06-11 Jeffery Schlom Process for producing monoclonal antibodies reactive with human breast cancer
US4446233A (en) * 1982-05-05 1984-05-01 E. I. Du Pont De Nemours And Company Homogeneous immunoassay using covalent hybrid antibodies
US4472509A (en) * 1982-06-07 1984-09-18 Gansow Otto A Metal chelate conjugated monoclonal antibodies
CA1260827A (en) * 1984-08-31 1989-09-26 Richard C. Siegel Antibody-metal ion complexes

Also Published As

Publication number Publication date
NO174136C (no) 1994-03-23
ATE68353T1 (de) 1991-11-15
FI861150A0 (fi) 1986-03-19
IL76183A0 (en) 1985-12-31
NO174136B (no) 1993-12-13
DK157086D0 (da) 1986-04-07
CA1275952C (en) 1990-11-06
CN85107873A (zh) 1987-05-06
AU587993B2 (en) 1989-09-07
DK157086A (da) 1986-04-07
JPS62500120A (ja) 1987-01-16
BR8506896A (pt) 1986-12-09
NO860938L (no) 1986-03-20
EP0193561A1 (en) 1986-09-10
US4722892A (en) 1988-02-02
FI87532B (fi) 1992-10-15
FI87532C (fi) 1993-01-25
EP0193561A4 (en) 1988-04-13
AU4778585A (en) 1986-03-24
EP0193561B1 (en) 1991-10-16
DE3584443D1 (de) 1991-11-21
WO1986001407A1 (en) 1986-03-13

Similar Documents

Publication Publication Date Title
FI861150A (fi) Monoklonala antikroppar mot metallkelat.
ZA978865B (en) Reshaped human anti-HM 1.24 antibody.
KR0137930B1 (en) Process for preparing isothiocyanato functionalized metal complexes
MY111961A (en) Therapeutic method
EP0536275A4 (en) Tissue-derived tumor growth inhibitors, methods of preparation and uses thereof
MY8600514A (en) Monoclonal-antibody-producing hybird cell line, antibody and method of preparing it, therepeutic composition containing it and its diagnostic and therapeutic uses
EP0174853A3 (en) Radiolabeled antibody fragments
CA2093928A1 (en) Monoclonal antibodies for detection and treatment of cancer
ZA897858B (en) Family of high affinity,modified antibodies for cancer treatment
IE830823L (en) Process and reagent for the determination of low density¹lipoproteins in body fluids
IT7924302A0 (it) Procedimento per migliorare le proprieta' magnetiche di un corpo metallico magnetico.
DE2963550D1 (en) Agent for treating allergic reactions
SE8305496D0 (sv) Forfarande for behandling av utslepp
ES8704082A1 (es) Procedimiento para preparar un agente terapeutico a base de celulas tumorales humanas y eventualmente, neuraminidasa.
YU46858B (sh) Postupak za dobijanje imunoglobulinskih konjugata
IE821855L (en) Glycerophosphocholines
ES8704962A1 (es) Un procedimiento para preparar 1b-d-ribofuranosil, 1-2-4-triazol-3-carboxamida.
JPS5615215A (en) Preparation of human immunoglobulin for intravenous injection with immobilized pepsin gel
EP0218587A4 (en) MONOCLONAL ANTIBODIES AND IMMUNIZATION METHOD USING THE SAME.
EP0193880A3 (de) Verfahren und Reagenz zur Bestimmung des Follikel stimulierenden Hormons sowie hierzu geeignete monoklonale Antikörper
AU1626492A (en) Monoclonal antibodies against the plasmin-antiplasmin complex, a method for the preparation thereof and the use thereof
DK182188A (da) Humant tumorassocieret antigen
RO78386A2 (ro) Procedeu de obtinere a unui medicament destinat tratamentului unor afectiuni ale prostatei si cailor urinare

Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: HYBRITECH INCORPORATED