ES8400145A1 - "procedimiento para la preparacion de polipeptidos inmunogenamente activos y producidos microbianamente, para la obtencion de una vacuna contra la fiebre aftosa". - Google Patents
"procedimiento para la preparacion de polipeptidos inmunogenamente activos y producidos microbianamente, para la obtencion de una vacuna contra la fiebre aftosa".Info
- Publication number
- ES8400145A1 ES8400145A1 ES513159A ES513159A ES8400145A1 ES 8400145 A1 ES8400145 A1 ES 8400145A1 ES 513159 A ES513159 A ES 513159A ES 513159 A ES513159 A ES 513159A ES 8400145 A1 ES8400145 A1 ES 8400145A1
- Authority
- ES
- Spain
- Prior art keywords
- coli
- produced
- fmdv
- plasmid
- foot
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 241000710198 Foot-and-mouth disease virus Species 0.000 title abstract 5
- 239000000427 antigen Substances 0.000 title abstract 2
- 102000036639 antigens Human genes 0.000 title abstract 2
- 108091007433 antigens Proteins 0.000 title abstract 2
- 208000007212 Foot-and-Mouth Disease Diseases 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 239000013612 plasmid Substances 0.000 abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 241000588724 Escherichia coli Species 0.000 abstract 2
- 108020001507 fusion proteins Proteins 0.000 abstract 2
- 102000037865 fusion proteins Human genes 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108020004705 Codon Proteins 0.000 abstract 1
- 241001646716 Escherichia coli K-12 Species 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 101150036700 VP3 gene Proteins 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 230000002860 competitive effect Effects 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 238000003127 radioimmunoassay Methods 0.000 abstract 1
- 238000010839 reverse transcription Methods 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32111—Aphthovirus, e.g. footandmouth disease virus
- C12N2770/32122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE UN POLIPEPTIDO INMUNOLOGICAMENTE ACTIVO, UTIL PARA OBTENER UNA VACUNA CONTRA LA FIEBRE AFTOSA.SE EMPLEA UN POLIPEPTIDO QUE COMPRENDE LA SECUENCIA DE AMINOACIDOS DE AL MENOS UN DETERMINANTE ANTIGENO DE PROTEINA DE VIRUS DE FIEBRE AFTOSA O BIEN DOS DETERMINANTES ANTIGENOS, PROVENIENTES DE, POR LO MENOS, DOS CEPAS DIFERENTES DEL VIRUS DE FIEBRE AFTOSA O UNO DE LOS PROCEDENTES POLIPEPTIDOS FUSIONADO CON UN POLIPEPTIDO DERIVADO DE LA EXPRESION DE ADN ADICIONAL; SE UTILIZA UN VEHICULO DE EXPRESION MICROBIANA, CAPAZ DE EXPRESARDICHO POLIPEPTIDO EN UN MICROORGANISMO TRANSFORMANTE. EL CULTIVO MICROBIANO TRANSFORMADO, ES UN CULTIVO DE E. COLI. EL VEHICULO MICROBIANO REPLICABLE SE SELECCIONA DEL GRUPO COMPUESTO POR PFM1; PFM2; PFM3; PFM10; PFM20; PFMB1; PFMC; PFMD; P FMF; Y PFMG.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27410381A | 1981-06-16 | 1981-06-16 | |
US37485582A | 1982-05-04 | 1982-05-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES513159A0 ES513159A0 (es) | 1983-11-01 |
ES8400145A1 true ES8400145A1 (es) | 1983-11-01 |
Family
ID=26956602
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES513159A Expired ES8400145A1 (es) | 1981-06-16 | 1982-06-16 | "procedimiento para la preparacion de polipeptidos inmunogenamente activos y producidos microbianamente, para la obtencion de una vacuna contra la fiebre aftosa". |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0068693A3 (es) |
BR (1) | BR8203507A (es) |
DK (1) | DK268882A (es) |
ES (1) | ES8400145A1 (es) |
GB (1) | GB2103622B (es) |
IE (1) | IE53375B1 (es) |
PT (1) | PT75050B (es) |
ZW (1) | ZW11982A1 (es) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8105516L (sv) * | 1980-09-18 | 1982-03-19 | Wellcome Found | Syntetisk dna och forfarande for framstellning derav |
US4719177A (en) * | 1981-04-20 | 1988-01-12 | Massachusetts Institute Of Technology | Production of complementary DNA representing RNA viral sequences by recombinant DNA methods and uses therefor |
CA1338705C (en) * | 1981-10-22 | 1996-11-12 | Roy Curtiss Iii | Vaccines obtained from antigenic gene products of recombinant genes |
EP0105346B1 (en) * | 1982-04-14 | 1991-11-13 | BITTLE, James L. | Synthetic picornavirus antigen |
US5230888A (en) * | 1982-05-06 | 1993-07-27 | Massachusetts Institute Of Technology | Production of neutralizing antibodies by polypeptide VP1 of enteroviruses and by oligopeptide fragments of polypeptide VP1 |
US4751083A (en) * | 1982-05-06 | 1988-06-14 | Massachusetts Institute Of Technology | Production of neutralizing antibodies by polypeptide VP1 of enteroviruses and by oligopeptide fragments of polypeptide VP1 |
EP0105481A1 (en) * | 1982-09-30 | 1984-04-18 | The Wellcome Foundation Limited | Novel antigens and vaccines containing them |
US4512922A (en) * | 1982-12-22 | 1985-04-23 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
US4599197A (en) * | 1982-12-22 | 1986-07-08 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
US4511503A (en) * | 1982-12-22 | 1985-04-16 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
US4620948A (en) * | 1982-12-22 | 1986-11-04 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
US4518526A (en) * | 1982-12-22 | 1985-05-21 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
WO1984003506A1 (en) * | 1983-03-08 | 1984-09-13 | Commw Serum Lab Commission | Antigenically active amino acid sequences |
US4769237A (en) * | 1983-03-25 | 1988-09-06 | Bittle James L | Synthetic picornavirus antigen |
NZ209308A (en) | 1983-08-30 | 1991-08-27 | Genentech Inc | Vaccine against hsv involving a truncated membrane-free derivative of a membrane-bound protein |
US4701416A (en) * | 1983-12-09 | 1987-10-20 | Cetus Corporation | Feline leukemia virus vaccine plasmids for fusion protein of the gp70 envelope protein of FELV |
US4732971A (en) * | 1985-06-03 | 1988-03-22 | Eli Lilly And Company | Synthetic vaccines for foot and mouth disease |
US5539092A (en) * | 1992-10-02 | 1996-07-23 | Arch Development Corporation | Cyanobacterial and plant acetyl-CoA carboxylase |
US6306636B1 (en) | 1997-09-19 | 2001-10-23 | Arch Development Corporation | Nucleic acid segments encoding wheat acetyl-CoA carboxylase |
NZ556635A (en) | 2004-12-22 | 2010-11-26 | Genentech Inc | Method for producing soluble multi-membrane-spanning proteins |
CN101795703B (zh) | 2007-06-27 | 2015-05-06 | 里兰斯坦福初级大学理事会 | 肽酪氨酸酶抑制剂及其应用 |
CN104792990A (zh) * | 2015-03-31 | 2015-07-22 | 洛阳莱普生信息科技有限公司 | 一种a型口蹄疫竞争elisa抗体检测试剂盒 |
CN105399802B (zh) * | 2015-12-08 | 2020-04-03 | 中国农业科学院兰州兽医研究所 | A型口蹄疫基因工程复合表位蛋白及疫苗 |
CN105622762B (zh) * | 2016-03-03 | 2020-04-03 | 中国农业科学院兰州兽医研究所 | 一种牛趋化因子介导的o型口蹄疫靶向性复合表位蛋白及疫苗 |
CN105777909B (zh) * | 2016-03-03 | 2020-04-03 | 中国农业科学院兰州兽医研究所 | 一种猪趋化因子介导的a型口蹄疫靶向性复合表位蛋白及疫苗 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK207681A (da) * | 1980-05-12 | 1981-11-13 | Biogen Nv | Dna-sekvenser rekombinations-dna-molekyler og fremgangsmaade klovsyge virale antigener til fremstilling af polypeptider med specificitet som mund og |
PH22618A (en) * | 1980-06-06 | 1988-10-28 | Biogen Nv | Improved vectors and method for making such vectors and for expressing cloned genes |
SE8105516L (sv) * | 1980-09-18 | 1982-03-19 | Wellcome Found | Syntetisk dna och forfarande for framstellning derav |
-
1982
- 1982-06-11 EP EP82303040A patent/EP0068693A3/en not_active Ceased
- 1982-06-11 GB GB08217060A patent/GB2103622B/en not_active Expired
- 1982-06-14 PT PT75050A patent/PT75050B/pt unknown
- 1982-06-14 ZW ZW119/82A patent/ZW11982A1/xx unknown
- 1982-06-15 DK DK268882A patent/DK268882A/da not_active Application Discontinuation
- 1982-06-15 IE IE1428/82A patent/IE53375B1/en unknown
- 1982-06-16 ES ES513159A patent/ES8400145A1/es not_active Expired
- 1982-06-16 BR BR8203507A patent/BR8203507A/pt unknown
Also Published As
Publication number | Publication date |
---|---|
GB2103622B (en) | 1986-01-15 |
EP0068693A2 (en) | 1983-01-05 |
PT75050A (en) | 1982-07-01 |
ES513159A0 (es) | 1983-11-01 |
DK268882A (da) | 1983-02-02 |
IE53375B1 (en) | 1988-10-26 |
ZW11982A1 (en) | 1982-11-10 |
BR8203507A (pt) | 1983-06-07 |
GB2103622A (en) | 1983-02-23 |
PT75050B (en) | 1984-02-21 |
EP0068693A3 (en) | 1983-07-20 |
IE821428L (en) | 1982-12-16 |
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