ATE480554T1 - Rekombinanter leukotoxinimpfstoff aus fusobacterium necrophorum und dessen präparation - Google Patents
Rekombinanter leukotoxinimpfstoff aus fusobacterium necrophorum und dessen präparationInfo
- Publication number
- ATE480554T1 ATE480554T1 AT01932626T AT01932626T ATE480554T1 AT E480554 T1 ATE480554 T1 AT E480554T1 AT 01932626 T AT01932626 T AT 01932626T AT 01932626 T AT01932626 T AT 01932626T AT E480554 T1 ATE480554 T1 AT E480554T1
- Authority
- AT
- Austria
- Prior art keywords
- gene
- leukotoxin
- protein
- necrophorum
- sequenced
- Prior art date
Links
- FBUKMFOXMZRGRB-UHFFFAOYSA-N Coronaric acid Natural products CCCCCC=CCC1OC1CCCCCCCC(O)=O FBUKMFOXMZRGRB-UHFFFAOYSA-N 0.000 title abstract 4
- 101710170970 Leukotoxin Proteins 0.000 title abstract 4
- 241000605952 Fusobacterium necrophorum Species 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 8
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 101100075612 Aggregatibacter actinomycetemcomitans ltxA gene Proteins 0.000 abstract 1
- 108700026244 Open Reading Frames Proteins 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000012228 culture supernatant Substances 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 230000005847 immunogenicity Effects 0.000 abstract 1
- 101150108880 lktA gene Proteins 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 238000011144 upstream manufacturing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55825700A | 2000-04-25 | 2000-04-25 | |
| US09/841,786 US6669940B2 (en) | 2000-04-25 | 2001-04-24 | Recombinant fusobacterium necrophorum leukotoxin vaccine and preparation thereof |
| PCT/US2001/013240 WO2001080886A2 (en) | 2000-04-25 | 2001-04-25 | Recombinant fusobacterium necrophorum leukotoxin vaccine and preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE480554T1 true ATE480554T1 (de) | 2010-09-15 |
Family
ID=24228816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01932626T ATE480554T1 (de) | 2000-04-25 | 2001-04-25 | Rekombinanter leukotoxinimpfstoff aus fusobacterium necrophorum und dessen präparation |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US6669940B2 (de) |
| AT (1) | ATE480554T1 (de) |
| DE (1) | DE60143029D1 (de) |
| ES (1) | ES2352322T3 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6669940B2 (en) * | 2000-04-25 | 2003-12-30 | Kansas University Research Foundation | Recombinant fusobacterium necrophorum leukotoxin vaccine and preparation thereof |
| AU2005280147B2 (en) * | 2004-08-25 | 2011-02-24 | Epitopix, Llc | Fusobacterium polypeptides and methods of use |
| EP2742875B1 (de) | 2007-11-14 | 2016-02-24 | Adhezion Biomedical, LLC | Cyanoacrylgewebehaftstoffe |
| US9308247B2 (en) | 2011-03-25 | 2016-04-12 | Kansas State University Research Foundation | Compositions and methods for detecting, treating, and protecting against fusobacterium infection |
| BR112015012288B1 (pt) | 2012-11-29 | 2022-07-26 | Cornell University | Uso de uma composição veterinária |
| BR112018009319A8 (pt) | 2015-11-09 | 2019-02-26 | Epitopix Llc | polipeptídeos de fusobacterium e métodos de uso |
| BR112022003788A2 (pt) * | 2019-08-27 | 2022-05-24 | Relica Genomics Inc | Plantas transformadas e métodos para produzir e usar as mesmas |
| CN110613842B (zh) * | 2019-10-15 | 2022-03-15 | 黑龙江八一农垦大学 | 一种牛坏死杆菌的亚单位疫苗及其制备方法 |
| CN111154904A (zh) * | 2020-03-02 | 2020-05-15 | 黑龙江八一农垦大学 | 坏死杆菌白细胞毒素基因pcr诊断试剂盒及其建立方法 |
| CN114686445B (zh) * | 2022-03-29 | 2023-07-07 | 黑龙江八一农垦大学 | 一种用于检测坏死杆菌白细胞毒素的单克隆抗体、试剂盒及其应用 |
| CN117288947B (zh) * | 2023-10-07 | 2024-09-24 | 黑龙江八一农垦大学 | 一种牛坏死杆菌抗体间接elisa检测试剂盒及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4203968A (en) | 1978-08-18 | 1980-05-20 | Iowa State University Research Foundation, Inc. | Combination vaccine for swine dysentery and method of use |
| US4152415A (en) | 1978-08-18 | 1979-05-01 | Iowa State University Research Foundation, Inc. | Method of increasing the effectiveness of oral vaccination for swine dysentery |
| US4919929A (en) | 1984-02-01 | 1990-04-24 | Stolle Research & Development Corporation | Mammal immunization |
| US5641653A (en) * | 1989-10-31 | 1997-06-24 | The Texas A&M University System | DNA encoding Actinobacillus pleuropneumoniae hemolysin |
| US5455034A (en) | 1992-06-26 | 1995-10-03 | Kansas State University Research Foundation | Fusobacterium necrophorum leukotoxoid vaccine |
| AU2001259138B2 (en) * | 2000-04-25 | 2007-06-07 | Kansas State University Research Foundation | Recombinant fusobacterium necrophorum leukotoxin vaccine and preparation thereof |
| US6669940B2 (en) * | 2000-04-25 | 2003-12-30 | Kansas University Research Foundation | Recombinant fusobacterium necrophorum leukotoxin vaccine and preparation thereof |
-
2001
- 2001-04-24 US US09/841,786 patent/US6669940B2/en not_active Expired - Lifetime
- 2001-04-25 AT AT01932626T patent/ATE480554T1/de not_active IP Right Cessation
- 2001-04-25 ES ES01932626T patent/ES2352322T3/es not_active Expired - Lifetime
- 2001-04-25 DE DE60143029T patent/DE60143029D1/de not_active Expired - Lifetime
-
2008
- 2008-07-11 US US12/171,985 patent/US20090117142A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20090117142A1 (en) | 2009-05-07 |
| DE60143029D1 (de) | 2010-10-21 |
| US20020054883A1 (en) | 2002-05-09 |
| ES2352322T3 (es) | 2011-02-17 |
| US6669940B2 (en) | 2003-12-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Schnepf et al. | Delineation of a toxin-encoding segment of a Bacillus thuringiensis crystal protein gene. | |
| MX9702714A (es) | Produccion de peptidos en plantas como fusiones de proteinas con revestimiento viral. | |
| DE60035419D1 (de) | Antigene peptide aus neisseria | |
| ATE480554T1 (de) | Rekombinanter leukotoxinimpfstoff aus fusobacterium necrophorum und dessen präparation | |
| BG102983A (en) | Extramembrane protein 106 polypeptide of moraxella catarrhalis, its gene sequence and application | |
| DE68929507D1 (de) | Rekombinante mykobakterielle expressions-träger sowie deren verwendung | |
| AR018603A1 (es) | Un peptido, util para el tratamiento y/o profilaxis de la enfermedad de alzheimer y el sindrome de down, las composiciones farmaceuticas y vacunas que locontienen, el uso de dicho peptido para la preparacion de las composiciones farmaceuticas, una secuencia de aislado de adn, un plasmido o vector vi | |
| ATE346931T1 (de) | Clostridium perfringens impfstoff | |
| ES2236718T3 (es) | Proteina portadora de efecto adyuvante, complejo inmunogenico que la contiene, su procedimiento de preparacion, secuencia nucleotidica y vacuna. | |
| BR9306109A (pt) | Gene e grupo de genes isolado e purifcado proteína com elevado peso molecular proteína com elevado peso molecular isolada e purificade conjugado e peptideo sintético | |
| Makoff et al. | Protective surface antigen P69 of Bordetella pertussis: its characterization and very high level expression in Escherichia coli | |
| DE69839848D1 (de) | Nicht identische gene und ihre anwendung in verbesserten molekularen adjuvanten | |
| DE69935599D1 (de) | Modifizierte hcv peptid-impfstoffe | |
| IL99079A0 (en) | Protein structure of the plant toxin gelonin | |
| Futaki et al. | Embodying a stable α-helical protein structure through efficient chemical ligation via thioether formation | |
| MY135991A (en) | A vaccine-induced hepatits b viral strain and uses thereof | |
| CA2158024A1 (en) | A mycoplasma gallisepticum antigen, dna encoding the antigen, recombinant vector bearing the dna and recombinant virus utilizing the recombinant vector as well as use thereof | |
| NO20011263L (no) | Moraxella Catarrhalis BASBO34-polypeptider og anvendelser derav | |
| PE20010237A1 (es) | GEN DERIVADO DE LAWSONIA Y POLIPEPTIDOS OmpH, PEPTIDOS Y PROTEINAS RELACIONADOS Y SUS USOS | |
| PE20010316A1 (es) | GEN DERIVADO DE LAWSONIA Y POLIPEPTIDOS, PEPTIDOS Y PROTEINAS FlgE RELACIONADOS Y SUS USOS | |
| WO2005058944A3 (en) | Immunogenic peptides fragments of xage-1 | |
| ATE474927T1 (de) | Schützende hochmolekulargewichtsproteine aus haemophilus influenzae | |
| WO2004056316A3 (en) | Vaccines against hiv-1 tat protein to generate neutralizing antibodies | |
| US20090220517A1 (en) | Method for producing epitomers and their uses on carrier microorganisms | |
| WO2001074847A3 (en) | T-cell epitope of mage-12 and related nucleic acids, vectors, cells, compositions and methods of inducing an immune response to cancer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |