ES8304557A1 - Un procedimiento para la preparacion de derivados de ciclo- hepteno. - Google Patents
Un procedimiento para la preparacion de derivados de ciclo- hepteno.Info
- Publication number
- ES8304557A1 ES8304557A1 ES508775A ES508775A ES8304557A1 ES 8304557 A1 ES8304557 A1 ES 8304557A1 ES 508775 A ES508775 A ES 508775A ES 508775 A ES508775 A ES 508775A ES 8304557 A1 ES8304557 A1 ES 8304557A1
- Authority
- ES
- Spain
- Prior art keywords
- cyclohepten
- dibenzo
- reduction
- pharmceuticals
- intermediates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 125000001162 cycloheptenyl group Chemical class C1(=CCCCCC1)* 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- ONQBOTKLCMXPOF-UHFFFAOYSA-N 1-ethylpyrrolidine Chemical compound CCN1CCCC1 ONQBOTKLCMXPOF-UHFFFAOYSA-N 0.000 abstract 2
- 206010020751 Hypersensitivity Diseases 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 208000035285 Allergic Seasonal Rhinitis Diseases 0.000 abstract 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 1
- 206010002198 Anaphylactic reaction Diseases 0.000 abstract 1
- 208000024780 Urticaria Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 230000036783 anaphylactic response Effects 0.000 abstract 1
- 208000003455 anaphylaxis Diseases 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- ZXIJMRYMVAMXQP-UHFFFAOYSA-N cycloheptene Chemical class C1CCC=CCC1 ZXIJMRYMVAMXQP-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 230000009610 hypersensitivity Effects 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/30—Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
- C07C2603/32—Dibenzocycloheptenes; Hydrogenated dibenzocycloheptenes
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH27381 | 1981-01-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES508775A0 ES508775A0 (es) | 1983-03-16 |
| ES8304557A1 true ES8304557A1 (es) | 1983-03-16 |
Family
ID=4183246
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES508775A Expired ES8304557A1 (es) | 1981-01-16 | 1982-01-15 | Un procedimiento para la preparacion de derivados de ciclo- hepteno. |
| ES517501A Granted ES517501A0 (es) | 1981-01-16 | 1982-11-19 | Un procedimiento para la preparacion de derivados de ciclohepteno. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES517501A Granted ES517501A0 (es) | 1981-01-16 | 1982-11-19 | Un procedimiento para la preparacion de derivados de ciclohepteno. |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US4513002A (en, 2012) |
| EP (1) | EP0056617B1 (en, 2012) |
| JP (1) | JPS57139021A (en, 2012) |
| KR (1) | KR880001863B1 (en, 2012) |
| AR (1) | AR229877A1 (en, 2012) |
| AT (1) | ATE16484T1 (en, 2012) |
| AU (1) | AU550523B2 (en, 2012) |
| CA (1) | CA1157853A (en, 2012) |
| DE (1) | DE3267334D1 (en, 2012) |
| DK (1) | DK17982A (en, 2012) |
| ES (2) | ES8304557A1 (en, 2012) |
| FI (1) | FI76572C (en, 2012) |
| GR (1) | GR75161B (en, 2012) |
| HU (1) | HU184981B (en, 2012) |
| IE (1) | IE51955B1 (en, 2012) |
| IL (1) | IL64755A (en, 2012) |
| MC (1) | MC1439A1 (en, 2012) |
| NO (1) | NO157374C (en, 2012) |
| NZ (1) | NZ199451A (en, 2012) |
| PH (1) | PH17091A (en, 2012) |
| PT (1) | PT74287A (en, 2012) |
| YU (1) | YU6782A (en, 2012) |
| ZA (1) | ZA82136B (en, 2012) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4513002A (en) * | 1981-01-16 | 1985-04-23 | Hoffmann-La Roche Inc. | Cycloheptene derivatives |
| US5049673A (en) * | 1987-10-30 | 1991-09-17 | The Regents Of The University Of California | Fluorescent indicator dyes for calcium working at long wavelengths |
| US4920025A (en) * | 1988-04-08 | 1990-04-24 | Xerox Corporation | Control of selenium alloy fractionation |
| US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| ZA200804550B (en) | 2005-11-09 | 2009-08-26 | Combinatorx Inc | Methods, compositions, and kits for the treatment of medical conditions |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3409640A (en) * | 1959-07-22 | 1968-11-05 | Schering Corp | 5-(3'-dimethylamino-2'-methyl-propyl)dibenzocycloheptenes |
| GB1017696A (en) * | 1961-09-25 | 1966-01-19 | Merck & Co Inc | Substituted 5h-dibenzo[a, d]cycloheptenes and 10,11-dihydro-5h-dibenzo[a, d]cycloheptenes |
| US3922305A (en) * | 1962-08-09 | 1975-11-25 | Merck & Co Inc | Chemical compounds |
| US4136116A (en) * | 1968-05-03 | 1979-01-23 | Hoffmann-La Roche Inc. | Tricyclic compounds |
| US4127717A (en) * | 1978-03-20 | 1978-11-28 | E. R. Squibb & Sons, Inc. | Benzo-cyclitolamines |
| US4513002A (en) * | 1981-01-16 | 1985-04-23 | Hoffmann-La Roche Inc. | Cycloheptene derivatives |
| US4337260A (en) * | 1981-09-10 | 1982-06-29 | Yoshitomi Pharmaceutical Industries, Ltd. | Imidazopyridine-spiro-piperidine compounds |
-
1981
- 1981-12-14 US US06/330,733 patent/US4513002A/en not_active Expired - Fee Related
- 1981-12-23 CA CA000393170A patent/CA1157853A/en not_active Expired
-
1982
- 1982-01-08 ZA ZA82136A patent/ZA82136B/xx unknown
- 1982-01-08 NZ NZ199451A patent/NZ199451A/en unknown
- 1982-01-11 AU AU79418/82A patent/AU550523B2/en not_active Ceased
- 1982-01-11 IL IL64755A patent/IL64755A/xx unknown
- 1982-01-12 HU HU8273A patent/HU184981B/hu unknown
- 1982-01-12 JP JP57002366A patent/JPS57139021A/ja active Pending
- 1982-01-13 AT AT82100204T patent/ATE16484T1/de not_active IP Right Cessation
- 1982-01-13 EP EP82100204A patent/EP0056617B1/de not_active Expired
- 1982-01-13 FI FI820106A patent/FI76572C/fi not_active IP Right Cessation
- 1982-01-13 AR AR288115A patent/AR229877A1/es active
- 1982-01-13 YU YU00067/82A patent/YU6782A/xx unknown
- 1982-01-13 DE DE8282100204T patent/DE3267334D1/de not_active Expired
- 1982-01-14 GR GR67001A patent/GR75161B/el unknown
- 1982-01-14 MC MC821569A patent/MC1439A1/xx unknown
- 1982-01-15 DK DK17982A patent/DK17982A/da unknown
- 1982-01-15 ES ES508775A patent/ES8304557A1/es not_active Expired
- 1982-01-15 PT PT74287A patent/PT74287A/pt unknown
- 1982-01-15 NO NO820125A patent/NO157374C/no unknown
- 1982-01-15 IE IE72/82A patent/IE51955B1/en unknown
- 1982-01-15 KR KR8200159A patent/KR880001863B1/ko not_active Expired
- 1982-01-15 PH PH26740A patent/PH17091A/en unknown
- 1982-11-19 ES ES517501A patent/ES517501A0/es active Granted
-
1985
- 1985-02-05 US US06/698,493 patent/US4691040A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IL64755A (en) | 1985-04-30 |
| YU6782A (en) | 1985-03-20 |
| ES8401760A1 (es) | 1984-01-01 |
| PH17091A (en) | 1984-05-29 |
| JPS57139021A (en) | 1982-08-27 |
| FI820106L (fi) | 1982-07-17 |
| FI76572C (fi) | 1988-11-10 |
| EP0056617A3 (en) | 1982-11-17 |
| IE51955B1 (en) | 1987-04-29 |
| IL64755A0 (en) | 1982-03-31 |
| NO820125L (no) | 1982-07-19 |
| NZ199451A (en) | 1984-12-14 |
| ES508775A0 (es) | 1983-03-16 |
| CA1157853A (en) | 1983-11-29 |
| AU7941882A (en) | 1982-07-22 |
| DK17982A (da) | 1982-07-17 |
| AU550523B2 (en) | 1986-03-27 |
| ES517501A0 (es) | 1984-01-01 |
| IE820072L (en) | 1982-07-16 |
| KR880001863B1 (ko) | 1988-09-23 |
| KR830009021A (ko) | 1983-12-17 |
| ZA82136B (en) | 1982-11-24 |
| US4513002A (en) | 1985-04-23 |
| NO157374B (no) | 1987-11-30 |
| HU184981B (en) | 1984-11-28 |
| DE3267334D1 (en) | 1985-12-19 |
| FI76572B (fi) | 1988-07-29 |
| EP0056617A2 (de) | 1982-07-28 |
| US4691040A (en) | 1987-09-01 |
| MC1439A1 (fr) | 1982-12-06 |
| ATE16484T1 (de) | 1985-11-15 |
| AR229877A1 (es) | 1983-12-30 |
| NO157374C (no) | 1988-03-09 |
| EP0056617B1 (de) | 1985-11-13 |
| PT74287A (en) | 1982-02-01 |
| GR75161B (en, 2012) | 1984-07-13 |
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