IL64755A - 1-(2-(4,5,10,11-tetrahydro-1h-dibenzo(a,d)cyclohepten-5-yl)-ethyl)pyrrolidine and pharmaceutically acceptable acid addition salts thereof,their preparation and pharmaceutical compositions containing them - Google Patents
1-(2-(4,5,10,11-tetrahydro-1h-dibenzo(a,d)cyclohepten-5-yl)-ethyl)pyrrolidine and pharmaceutically acceptable acid addition salts thereof,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL64755A IL64755A IL64755A IL6475582A IL64755A IL 64755 A IL64755 A IL 64755A IL 64755 A IL64755 A IL 64755A IL 6475582 A IL6475582 A IL 6475582A IL 64755 A IL64755 A IL 64755A
- Authority
- IL
- Israel
- Prior art keywords
- cyclohepten
- dibenzo
- pyrrolidine
- tetrahydro
- ethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/30—Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
- C07C2603/32—Dibenzocycloheptenes; Hydrogenated dibenzocycloheptenes
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH27381 | 1981-01-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL64755A0 IL64755A0 (en) | 1982-03-31 |
| IL64755A true IL64755A (en) | 1985-04-30 |
Family
ID=4183246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL64755A IL64755A (en) | 1981-01-16 | 1982-01-11 | 1-(2-(4,5,10,11-tetrahydro-1h-dibenzo(a,d)cyclohepten-5-yl)-ethyl)pyrrolidine and pharmaceutically acceptable acid addition salts thereof,their preparation and pharmaceutical compositions containing them |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US4513002A (xx) |
| EP (1) | EP0056617B1 (xx) |
| JP (1) | JPS57139021A (xx) |
| KR (1) | KR880001863B1 (xx) |
| AR (1) | AR229877A1 (xx) |
| AT (1) | ATE16484T1 (xx) |
| AU (1) | AU550523B2 (xx) |
| CA (1) | CA1157853A (xx) |
| DE (1) | DE3267334D1 (xx) |
| DK (1) | DK17982A (xx) |
| ES (2) | ES8304557A1 (xx) |
| FI (1) | FI76572C (xx) |
| GR (1) | GR75161B (xx) |
| HU (1) | HU184981B (xx) |
| IE (1) | IE51955B1 (xx) |
| IL (1) | IL64755A (xx) |
| MC (1) | MC1439A1 (xx) |
| NO (1) | NO157374C (xx) |
| NZ (1) | NZ199451A (xx) |
| PH (1) | PH17091A (xx) |
| PT (1) | PT74287A (xx) |
| YU (1) | YU6782A (xx) |
| ZA (1) | ZA82136B (xx) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4513002A (en) * | 1981-01-16 | 1985-04-23 | Hoffmann-La Roche Inc. | Cycloheptene derivatives |
| US5049673A (en) * | 1987-10-30 | 1991-09-17 | The Regents Of The University Of California | Fluorescent indicator dyes for calcium working at long wavelengths |
| US4920025A (en) * | 1988-04-08 | 1990-04-24 | Xerox Corporation | Control of selenium alloy fractionation |
| US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| EP2218442A1 (en) | 2005-11-09 | 2010-08-18 | CombinatoRx, Inc. | Methods, compositions, and kits for the treatment of ophthalmic disorders |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3409640A (en) * | 1959-07-22 | 1968-11-05 | Schering Corp | 5-(3'-dimethylamino-2'-methyl-propyl)dibenzocycloheptenes |
| GB1017696A (en) * | 1961-09-25 | 1966-01-19 | Merck & Co Inc | Substituted 5h-dibenzo[a, d]cycloheptenes and 10,11-dihydro-5h-dibenzo[a, d]cycloheptenes |
| US3922305A (en) * | 1962-08-09 | 1975-11-25 | Merck & Co Inc | Chemical compounds |
| US4136116A (en) * | 1968-05-03 | 1979-01-23 | Hoffmann-La Roche Inc. | Tricyclic compounds |
| US4127717A (en) * | 1978-03-20 | 1978-11-28 | E. R. Squibb & Sons, Inc. | Benzo-cyclitolamines |
| US4513002A (en) * | 1981-01-16 | 1985-04-23 | Hoffmann-La Roche Inc. | Cycloheptene derivatives |
| US4337260A (en) * | 1981-09-10 | 1982-06-29 | Yoshitomi Pharmaceutical Industries, Ltd. | Imidazopyridine-spiro-piperidine compounds |
-
1981
- 1981-12-14 US US06/330,733 patent/US4513002A/en not_active Expired - Fee Related
- 1981-12-23 CA CA000393170A patent/CA1157853A/en not_active Expired
-
1982
- 1982-01-08 ZA ZA82136A patent/ZA82136B/xx unknown
- 1982-01-08 NZ NZ199451A patent/NZ199451A/en unknown
- 1982-01-11 AU AU79418/82A patent/AU550523B2/en not_active Ceased
- 1982-01-11 IL IL64755A patent/IL64755A/xx unknown
- 1982-01-12 JP JP57002366A patent/JPS57139021A/ja active Pending
- 1982-01-12 HU HU8273A patent/HU184981B/hu unknown
- 1982-01-13 AT AT82100204T patent/ATE16484T1/de not_active IP Right Cessation
- 1982-01-13 FI FI820106A patent/FI76572C/fi not_active IP Right Cessation
- 1982-01-13 YU YU00067/82A patent/YU6782A/xx unknown
- 1982-01-13 AR AR288115A patent/AR229877A1/es active
- 1982-01-13 EP EP82100204A patent/EP0056617B1/de not_active Expired
- 1982-01-13 DE DE8282100204T patent/DE3267334D1/de not_active Expired
- 1982-01-14 GR GR67001A patent/GR75161B/el unknown
- 1982-01-14 MC MC821569A patent/MC1439A1/xx unknown
- 1982-01-15 DK DK17982A patent/DK17982A/da unknown
- 1982-01-15 ES ES508775A patent/ES8304557A1/es not_active Expired
- 1982-01-15 PH PH26740A patent/PH17091A/en unknown
- 1982-01-15 IE IE72/82A patent/IE51955B1/en unknown
- 1982-01-15 NO NO820125A patent/NO157374C/no unknown
- 1982-01-15 PT PT74287A patent/PT74287A/pt unknown
- 1982-01-15 KR KR8200159A patent/KR880001863B1/ko active
- 1982-11-19 ES ES517501A patent/ES517501A0/es active Granted
-
1985
- 1985-02-05 US US06/698,493 patent/US4691040A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0056617B1 (de) | 1985-11-13 |
| ES8401760A1 (es) | 1984-01-01 |
| FI820106L (fi) | 1982-07-17 |
| MC1439A1 (fr) | 1982-12-06 |
| JPS57139021A (en) | 1982-08-27 |
| AU7941882A (en) | 1982-07-22 |
| IE820072L (en) | 1982-07-16 |
| KR830009021A (ko) | 1983-12-17 |
| PH17091A (en) | 1984-05-29 |
| HU184981B (en) | 1984-11-28 |
| FI76572B (fi) | 1988-07-29 |
| FI76572C (fi) | 1988-11-10 |
| NO157374B (no) | 1987-11-30 |
| US4513002A (en) | 1985-04-23 |
| EP0056617A3 (en) | 1982-11-17 |
| NO820125L (no) | 1982-07-19 |
| NO157374C (no) | 1988-03-09 |
| AU550523B2 (en) | 1986-03-27 |
| ES517501A0 (es) | 1984-01-01 |
| KR880001863B1 (ko) | 1988-09-23 |
| DK17982A (da) | 1982-07-17 |
| IL64755A0 (en) | 1982-03-31 |
| ATE16484T1 (de) | 1985-11-15 |
| ES508775A0 (es) | 1983-03-16 |
| CA1157853A (en) | 1983-11-29 |
| IE51955B1 (en) | 1987-04-29 |
| GR75161B (xx) | 1984-07-13 |
| ZA82136B (en) | 1982-11-24 |
| US4691040A (en) | 1987-09-01 |
| DE3267334D1 (en) | 1985-12-19 |
| YU6782A (en) | 1985-03-20 |
| ES8304557A1 (es) | 1983-03-16 |
| EP0056617A2 (de) | 1982-07-28 |
| PT74287A (en) | 1982-02-01 |
| AR229877A1 (es) | 1983-12-30 |
| NZ199451A (en) | 1984-12-14 |
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