ES8304123A1 - Procedimiento para preparar derivados de piridina. - Google Patents

Procedimiento para preparar derivados de piridina.

Info

Publication number
ES8304123A1
ES8304123A1 ES506986A ES506986A ES8304123A1 ES 8304123 A1 ES8304123 A1 ES 8304123A1 ES 506986 A ES506986 A ES 506986A ES 506986 A ES506986 A ES 506986A ES 8304123 A1 ES8304123 A1 ES 8304123A1
Authority
ES
Spain
Prior art keywords
benzoxadiazol
dicarboxylates
dihydro
pyridine
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES506986A
Other languages
English (en)
Other versions
ES506986A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES506986A0 publication Critical patent/ES506986A0/es
Publication of ES8304123A1 publication Critical patent/ES8304123A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE PIRIDINA DE FORMULA (I), EN LA QUE COOR Y COOR SON GRUPOS DE ESTER DE ACIDO CARBOXILICO; Y R ES HIDROGENO O ACILO. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UNA AMIDINA DE FORMULA (III), EN LAS QUE TODOS LOS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO, TAL COMO ETANOL, A UNA TEMPERATURA ENTRE LA AMBIENTE Y LA DE REFLUJO DEL DISOLVENTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE LAS ENFERMEDADES CORONARIAS Y CEREBROVASCULARES Y POR SU ACTIVIDAD ANTIHIPERTENSIVA.
ES506986A 1980-11-10 1981-11-10 Procedimiento para preparar derivados de piridina. Expired ES8304123A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH832780 1980-11-10

Publications (2)

Publication Number Publication Date
ES506986A0 ES506986A0 (es) 1983-02-16
ES8304123A1 true ES8304123A1 (es) 1983-02-16

Family

ID=4338627

Family Applications (1)

Application Number Title Priority Date Filing Date
ES506986A Expired ES8304123A1 (es) 1980-11-10 1981-11-10 Procedimiento para preparar derivados de piridina.

Country Status (15)

Country Link
JP (1) JPS57108089A (es)
AU (1) AU7732381A (es)
BE (1) BE891032A (es)
DE (1) DE3143649A1 (es)
DK (1) DK494781A (es)
ES (1) ES8304123A1 (es)
FI (1) FI813460L (es)
FR (1) FR2493847A1 (es)
GB (1) GB2086901A (es)
IL (1) IL64244A0 (es)
IT (1) IT1189050B (es)
NL (1) NL8105035A (es)
PT (1) PT73943B (es)
SE (1) SE8106633L (es)
ZA (1) ZA817774B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4414213A (en) * 1982-03-22 1983-11-08 Mead Johnson & Company Dihydropyridyl cyclic imidate esters and their pharmaceutical use
FR2528431B1 (fr) * 1982-06-15 1986-01-10 Sandoz Sa Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2210674C3 (de) * 1972-03-06 1981-09-24 Bayer Ag, 5090 Leverkusen 2-Amino-6-methyl-1,4-dihydropyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
FI64938C (fi) * 1977-06-20 1984-02-10 Sandoz Ag Foerfarande foer framstaellning av nya terapeutiskt anvaendbara bensoxa- och bensotiadiazolyl-1,4-dihydropyridinderivat
DK525179A (da) * 1978-12-18 1980-06-19 Sandoz Ag Fremgangsmaade til fremstilling af benzoxadiazoler og benzothiazoler

Also Published As

Publication number Publication date
IL64244A0 (en) 1982-02-28
DE3143649A1 (de) 1982-07-01
JPS57108089A (en) 1982-07-05
ES506986A0 (es) 1983-02-16
BE891032A (fr) 1982-05-10
GB2086901A (en) 1982-05-19
ZA817774B (en) 1983-06-29
AU7732381A (en) 1982-05-20
DK494781A (da) 1982-05-11
NL8105035A (nl) 1982-06-01
IT1189050B (it) 1988-01-28
FR2493847A1 (fr) 1982-05-14
PT73943B (en) 1983-07-14
PT73943A (en) 1981-12-01
SE8106633L (sv) 1982-05-11
FI813460L (fi) 1982-05-11
IT8149677A0 (it) 1981-11-10

Similar Documents

Publication Publication Date Title
MX9203338A (es) Nuevos derivados del oxico a_nor-esteroide-3-carboxilico.
IT1170996B (it) Perfezionamento nelle strutture di composizioni catalitiche per l'ossidazione parziale di n-butano ad anidride maleica
ATE40884T1 (de) Zwischenverbindungen fuer die herstellung von omeprazol.
BE859817A (fr) Compositions notamment utiles pour le traitement de l'acne
PT76472A (de) Neue derivate von cycloalka<c>pyrrol-carbonsaeuren verfahren zu ihrer herstellung diese enthaltende mittel und deren verwendung sowie neue cycloalka<c>pyrrol-carbonsaeuren als zwischenstufen und verfahren zu deren herstellung
JPS5223001A (en) Process for elimination of formyl group
IT1087971B (it) Processo per l'esterificazione di anidridi succiniche idrocarbil-sostituite.
BE837662A (fr) Composition gelifiee contenant de la tretinoine pour le traitement de l'acne
FR2334013A1 (fr) Revetement protegeant de l'oxydation pour disques de freins au carbone
ES8304123A1 (es) Procedimiento para preparar derivados de piridina.
ES8106276A1 (es) Un procedimiento para la preparacion de amidas del acido po-liprenilcarboxilico
DE3672446D1 (en) Pantothenolderivate.
SU694557A1 (ru) Сталь
JPS522941A (en) Traction elevator
ES451053A1 (es) Un procedimiento para la preparacion de nuevas penicilinas cefalosporinas.
ATE84780T1 (de) Neue di(meth)acrylate, verfahren zu deren herstellung und deren verwendung.
GB1532046A (en) Glass
JPS51138691A (en) Process for preparing novel b is-penicillins
JPS5220308A (en) Apparatus for continuously supplying raw materials in steel making
JPS5246067A (en) Reduction of optically active 5-oxo-2-pyrrolidinacetic acid esters
DE3669508D1 (de) Verbrueckungsreagenz, verfahren zu seiner herstellung und seine anwendung.
JPS51141874A (en) 6-aminochroman linolic acid amides.
JPS5230475A (en) Apparatus for measuring power line voltage
FI842639A (fi) Acylderivat av 1,4,3,6-dianhydro- hexitol.
DE69313291D1 (de) Phosphonoessigsäure und ester als antientzündungsmittel