DE69313291D1 - Phosphonoessigsäure und ester als antientzündungsmittel - Google Patents
Phosphonoessigsäure und ester als antientzündungsmittelInfo
- Publication number
- DE69313291D1 DE69313291D1 DE69313291T DE69313291T DE69313291D1 DE 69313291 D1 DE69313291 D1 DE 69313291D1 DE 69313291 T DE69313291 T DE 69313291T DE 69313291 T DE69313291 T DE 69313291T DE 69313291 D1 DE69313291 D1 DE 69313291D1
- Authority
- DE
- Germany
- Prior art keywords
- image
- ignitant
- ester
- phosphonoacetic acid
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- XUYJLQHKOGNDPB-UHFFFAOYSA-N phosphonoacetic acid Chemical compound OC(=O)CP(O)(O)=O XUYJLQHKOGNDPB-UHFFFAOYSA-N 0.000 title 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 229940124346 antiarthritic agent Drugs 0.000 abstract 1
- 239000003435 antirheumatic agent Substances 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4056—Esters of arylalkanephosphonic acids
- C07F9/4059—Compounds containing the structure (RY)2P(=X)-(CH2)n-C(=O)-(CH2)m-Ar, (X, Y = O, S, Se; n>=1, m>=0)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F17/00—Metallocenes
- C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4018—Esters of cycloaliphatic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6503—Five-membered rings
- C07F9/65031—Five-membered rings having the nitrogen atoms in the positions 1 and 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US92687992A | 1992-08-07 | 1992-08-07 | |
PCT/US1993/005365 WO1994003463A1 (en) | 1992-08-07 | 1993-06-09 | Phosphonoacetic esters and acids as anti-inflammatories |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69313291D1 true DE69313291D1 (de) | 1997-09-25 |
Family
ID=25453835
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69313291T Expired - Lifetime DE69313291D1 (de) | 1992-08-07 | 1993-06-09 | Phosphonoessigsäure und ester als antientzündungsmittel |
Country Status (13)
Country | Link |
---|---|
US (2) | US5565441A (de) |
EP (1) | EP0654035B1 (de) |
JP (1) | JPH07509712A (de) |
CN (1) | CN1086218A (de) |
AT (1) | ATE157097T1 (de) |
AU (1) | AU4407493A (de) |
DE (1) | DE69313291D1 (de) |
IL (1) | IL106435A0 (de) |
MX (1) | MX9304780A (de) |
PH (1) | PH30956A (de) |
TW (1) | TW226021B (de) |
WO (1) | WO1994003463A1 (de) |
ZA (1) | ZA935380B (de) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004066469A2 (en) * | 2003-01-22 | 2004-08-05 | Valence Technology, Inc. | Electrolyte for use in phosphate based lithium ion/polymer cells |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3683080A (en) * | 1970-08-28 | 1972-08-08 | Procter & Gamble | Compositions for inhibiting anomalous deposition and mobilization of calcium phosphate in animal tissue |
DE2310450A1 (de) * | 1973-03-02 | 1974-09-05 | Henkel & Cie Gmbh | Komplexbildner fuer mehrwertige metallionen |
DE2360797C2 (de) * | 1973-12-06 | 1985-05-23 | Henkel KGaA, 4000 Düsseldorf | Pharmazeutische Präparate |
FR2531088B1 (fr) * | 1982-07-29 | 1987-08-28 | Sanofi Sa | Produits anti-inflammatoires derives de l'acide methylenediphosphonique et leur procede de preparation |
PH27078A (en) * | 1984-12-21 | 1993-02-01 | Procter & Gamble | Pharmaceutical compositions containing geminal diphosphonates |
US5071840A (en) * | 1986-12-19 | 1991-12-10 | Norwich Eaton Pharmaceuticals, Inc. | Certain heterocyclic substituted diphosphonate compounds pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism |
IL84731A0 (en) * | 1986-12-19 | 1988-05-31 | Norwich Eaton Pharma | Heterocycle-substituted diphosphonic acids and salts and esters and pharmaceutical compositions containing them |
IT1242565B (it) * | 1990-09-14 | 1994-05-16 | Marposs Spa | Apparecchiatura per il controllo di una pluralita' di pezzi meccanici e relativo metodo di controllo. |
EP0521622B1 (de) * | 1991-07-03 | 1997-08-13 | PHARMACIA & UPJOHN COMPANY | Pyrazolopyrimiden- und Pyrimidinylbisphosphonsäureester als entzündungshemmende Mittel |
US5312814A (en) * | 1992-12-09 | 1994-05-17 | Bristol-Myers Squibb Co. | α-phosphonocarboxylate squalene synthetase inhibitors |
-
1993
- 1993-06-09 JP JP6505275A patent/JPH07509712A/ja active Pending
- 1993-06-09 AT AT93914399T patent/ATE157097T1/de active
- 1993-06-09 EP EP93914399A patent/EP0654035B1/de not_active Expired - Lifetime
- 1993-06-09 AU AU44074/93A patent/AU4407493A/en not_active Abandoned
- 1993-06-09 DE DE69313291T patent/DE69313291D1/de not_active Expired - Lifetime
- 1993-06-09 WO PCT/US1993/005365 patent/WO1994003463A1/en active IP Right Grant
- 1993-07-16 TW TW082105671A patent/TW226021B/zh active
- 1993-07-21 IL IL106435A patent/IL106435A0/xx unknown
- 1993-07-26 ZA ZA935380A patent/ZA935380B/xx unknown
- 1993-08-06 PH PH46642A patent/PH30956A/en unknown
- 1993-08-06 MX MX9304780A patent/MX9304780A/es unknown
- 1993-08-07 CN CN93116258A patent/CN1086218A/zh active Pending
-
1995
- 1995-02-01 US US08/382,240 patent/US5565441A/en not_active Expired - Fee Related
-
1996
- 1996-05-29 US US08/654,801 patent/US5643895A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0654035A1 (de) | 1995-05-24 |
CN1086218A (zh) | 1994-05-04 |
PH30956A (en) | 1997-12-23 |
EP0654035B1 (de) | 1997-08-20 |
US5565441A (en) | 1996-10-15 |
TW226021B (de) | 1994-07-01 |
JPH07509712A (ja) | 1995-10-26 |
ATE157097T1 (de) | 1997-09-15 |
ZA935380B (en) | 1995-01-26 |
IL106435A0 (en) | 1993-11-15 |
AU4407493A (en) | 1994-03-03 |
MX9304780A (es) | 1994-02-28 |
US5643895A (en) | 1997-07-01 |
WO1994003463A1 (en) | 1994-02-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU586248B2 (en) | (Meth)-acrylic acid esters and their use | |
DE3762412D1 (de) | (meth)acrylsaeureester und ihre verwendung zur herstellung von dentalmassen. | |
GB2306958B (en) | Oximesulfonic acid esters and the use thereof as latent sulfonic acids | |
EP0604641A4 (de) | Zusammensetzung, die aminderivate oder aminverwandte derivate der benzoesäure enthält, und ihre verwendung einschliesslich der behandlung von entzündlichen erkrankungen. | |
FI972865A (fi) | Hydroksimetyyli-imidatsodiatseptiinejä ja niiden esterit | |
ATE152728T1 (de) | Pyrazolopyrimidin- und pyrimidinylbisphosphonsäureester als entzündungshemmende mittel | |
FR2354091A1 (fr) | Utilisation d'esters aliphatiques d'acide 2-methyl-2-alkylalcanoiques comme matieres aromatiques et compositions de parfums en contenant | |
FI802559A (fi) | Foerfarande och anordning foer utfodring av djur i synnerhet grisar och svin | |
BR9611472A (pt) | Compostos de di-terc-butilfenol contendo enxofre úteis como agentes antiinflamatórios | |
ATE151067T1 (de) | Vpa-analoge antiepileptika | |
DE69313291D1 (de) | Phosphonoessigsäure und ester als antientzündungsmittel | |
FR2355822A1 (fr) | Derives d'esters de l'acide indolacetique. utiles comme anti-inflammatoires et analgesiques | |
BE875142A (fr) | Compositions anaerobies stabilisees contenant des acides | |
BR9707342A (pt) | Dihidrobensofurano e compostos correlatod úteis como agentes antiinflamatórios | |
ATE181388T1 (de) | Modulare, nutzungsflexible hausanordnung | |
ES8403922A1 (es) | "procedimiento para preparar nuevos esteres de acido tiolfosforico" | |
DE69203142D1 (de) | Von l-Glutaminsäure abgeleitete Süssungsmittel, Verfahren zu ihrer Herstellung. | |
DE59403903D1 (de) | Verfahren zur Herstellung von gegebenfalls 2-substituierten 5-Chlorimidazolen | |
FI934252A (fi) | 1,5,6,7-tetrahydro-4H-indazol-4-oner innehaollande laekemedel, nya 1,5,6,7-tetrahydro-4H-indazol-4-oner och foerfarande foer deras framstaellning | |
JPS56142260A (en) | 2-azetidinone and its preparation | |
CA2073673A1 (en) | Esters of 2-arylmethyl-1-naphthol derivatives as 5-lipoxygenase inhibitors |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |