PH30956A - Phosphonoacetic esters and acids as anti-inflammatories. - Google Patents

Phosphonoacetic esters and acids as anti-inflammatories.

Info

Publication number
PH30956A
PH30956A PH46642A PH46642A PH30956A PH 30956 A PH30956 A PH 30956A PH 46642 A PH46642 A PH 46642A PH 46642 A PH46642 A PH 46642A PH 30956 A PH30956 A PH 30956A
Authority
PH
Philippines
Prior art keywords
image
inflammatories
acids
phosphonoacetic
esters
Prior art date
Application number
PH46642A
Other languages
English (en)
Inventor
Nugent Richard Allen
Anderson David John
Schlachter Stephe Thomas
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of PH30956A publication Critical patent/PH30956A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4056Esters of arylalkanephosphonic acids
    • C07F9/4059Compounds containing the structure (RY)2P(=X)-(CH2)n-C(=O)-(CH2)m-Ar, (X, Y = O, S, Se; n>=1, m>=0)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F17/00Metallocenes
    • C07F17/02Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4018Esters of cycloaliphatic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/58Pyridine rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503Five-membered rings
    • C07F9/65031Five-membered rings having the nitrogen atoms in the positions 1 and 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509Six-membered rings
    • C07F9/6512Six-membered rings having the nitrogen atoms in positions 1 and 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PH46642A 1992-08-07 1993-08-06 Phosphonoacetic esters and acids as anti-inflammatories. PH30956A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US92687992A 1992-08-07 1992-08-07

Publications (1)

Publication Number Publication Date
PH30956A true PH30956A (en) 1997-12-23

Family

ID=25453835

Family Applications (1)

Application Number Title Priority Date Filing Date
PH46642A PH30956A (en) 1992-08-07 1993-08-06 Phosphonoacetic esters and acids as anti-inflammatories.

Country Status (13)

Country Link
US (2) US5565441A (de)
EP (1) EP0654035B1 (de)
JP (1) JPH07509712A (de)
CN (1) CN1086218A (de)
AT (1) ATE157097T1 (de)
AU (1) AU4407493A (de)
DE (1) DE69313291D1 (de)
IL (1) IL106435A0 (de)
MX (1) MX9304780A (de)
PH (1) PH30956A (de)
TW (1) TW226021B (de)
WO (1) WO1994003463A1 (de)
ZA (1) ZA935380B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100372162C (zh) * 2003-01-22 2008-02-27 威伦斯技术公司 锂电池组

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3683080A (en) * 1970-08-28 1972-08-08 Procter & Gamble Compositions for inhibiting anomalous deposition and mobilization of calcium phosphate in animal tissue
DE2310450A1 (de) * 1973-03-02 1974-09-05 Henkel & Cie Gmbh Komplexbildner fuer mehrwertige metallionen
DE2360797C2 (de) * 1973-12-06 1985-05-23 Henkel KGaA, 4000 Düsseldorf Pharmazeutische Präparate
FR2531088B1 (fr) * 1982-07-29 1987-08-28 Sanofi Sa Produits anti-inflammatoires derives de l'acide methylenediphosphonique et leur procede de preparation
PH27078A (en) * 1984-12-21 1993-02-01 Procter & Gamble Pharmaceutical compositions containing geminal diphosphonates
IL84731A0 (en) * 1986-12-19 1988-05-31 Norwich Eaton Pharma Heterocycle-substituted diphosphonic acids and salts and esters and pharmaceutical compositions containing them
US5071840A (en) * 1986-12-19 1991-12-10 Norwich Eaton Pharmaceuticals, Inc. Certain heterocyclic substituted diphosphonate compounds pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism
IT1242565B (it) * 1990-09-14 1994-05-16 Marposs Spa Apparecchiatura per il controllo di una pluralita' di pezzi meccanici e relativo metodo di controllo.
EP0521622B1 (de) * 1991-07-03 1997-08-13 PHARMACIA & UPJOHN COMPANY Pyrazolopyrimiden- und Pyrimidinylbisphosphonsäureester als entzündungshemmende Mittel
US5312814A (en) * 1992-12-09 1994-05-17 Bristol-Myers Squibb Co. α-phosphonocarboxylate squalene synthetase inhibitors

Also Published As

Publication number Publication date
JPH07509712A (ja) 1995-10-26
TW226021B (de) 1994-07-01
EP0654035A1 (de) 1995-05-24
WO1994003463A1 (en) 1994-02-17
CN1086218A (zh) 1994-05-04
AU4407493A (en) 1994-03-03
EP0654035B1 (de) 1997-08-20
DE69313291D1 (de) 1997-09-25
US5643895A (en) 1997-07-01
IL106435A0 (en) 1993-11-15
ZA935380B (en) 1995-01-26
ATE157097T1 (de) 1997-09-15
MX9304780A (es) 1994-02-28
US5565441A (en) 1996-10-15

Similar Documents

Publication Publication Date Title
UA35592C2 (uk) Похідні оцтової кислоти
CA2502856A1 (en) Intermediates for retroviral protease inhibiting compounds
GR3036867T3 (en) Hydroxymethylimidazodiazepines and their esters
IT1118335B (it) Convertitore per l'alimentazione di lampade a scarica e,piu' in generale,di lampade ad arco,e sua applicazione ai proiettori per dette lampade
AU4575279A (en) 17 beta-thiocarboxylic acid esters of 4-halo-3-oxoandrost-4- enes
HU9400003D0 (en) Pyrazolopyrimidine and pyrimidinyl bisphosphonic esters as anti-inflammatories
NO934512L (no) Fremgangsmåte for fremstilling av karbonmonoksydrik gass
ATE214698T1 (de) Neue carbamazepin hapten analoge
FI802559A (fi) Foerfarande och anordning foer utfodring av djur i synnerhet grisar och svin
IE780552L (en) Esters and thiolesters of amino acids
NZ322777A (en) Sulfur containing di-tert-butylphenol compounds useful as anti-inflammatory agents
CA2108584A1 (en) Substituted Azetidinones as Anti-Inflammatory and Antidegenerative Agents
PH30956A (en) Phosphonoacetic esters and acids as anti-inflammatories.
DK0602961T3 (da) Hudbehandlingssammensætning af lanolin/lanolinsyreestere
JPS5519214A (en) 2-acyl-6-aminomethylphenol derivative and its preparation
MY104238A (en) Prodrugs of antiinflammatory 3-acyl-2-oxindole-1 -carboxamides.
IL85403A0 (en) Thionophosphonic acid esters,their preparation and their use as pesticides
JPS6492A (en) Novel glycerin derivative, production thereof, hypotensor containing said derivative
GR75173B (de)
ATE16100T1 (de) Ester der 1-methyl-5-p-toluoylpyrrolyl-2essigs|ure mit antiinflammatorischen, mucolytischen und antitussiven eigenschaften, verfahren zu seiner herstellung und diese enthaltende pharmazeutische zusammensetzungen.
NZ238124A (en) Heterocyclylalkylphosphonic acid and ester derivatives and pharmacueitcal compositions
EP0305837A3 (en) Thiono-phosphonic-acid ester
JPS57206691A (en) 6,10,14,18-tetramethyl-5,9,13,17-nonadecatetraene-2-yl phosphoric ester
CA2073673A1 (en) Esters of 2-arylmethyl-1-naphthol derivatives as 5-lipoxygenase inhibitors
IE800978L (en) Esters of 2-(6-methoxy-2-naphthyl)-1-propanol