ES8303094A1 - "un procedimiento de tratamiento termico para inactivar el virus de hepatitis en una globulina insoluble en frio". - Google Patents

"un procedimiento de tratamiento termico para inactivar el virus de hepatitis en una globulina insoluble en frio".

Info

Publication number
ES8303094A1
ES8303094A1 ES509833A ES509833A ES8303094A1 ES 8303094 A1 ES8303094 A1 ES 8303094A1 ES 509833 A ES509833 A ES 509833A ES 509833 A ES509833 A ES 509833A ES 8303094 A1 ES8303094 A1 ES 8303094A1
Authority
ES
Spain
Prior art keywords
aqueous solution
cold insoluble
insoluble globulin
heat treatment
solution containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES509833A
Other languages
English (en)
Other versions
ES509833A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Green Cross Corp Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp Japan filed Critical Green Cross Corp Japan
Publication of ES509833A0 publication Critical patent/ES509833A0/es
Publication of ES8303094A1 publication Critical patent/ES8303094A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/04—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROCEDIMIENTO PARA INACTIVAR EL VIRUS DE LA HEPATITIS EN UNA GLOBULINA INSOLUBLE EN FRIO, MEDIANTE TRATAMIENTO TERMICO. CONSISTE EN CALENTAR ENTRE 50 A 80 C UNA DISOLUCION ACUOSA QUE CONTIENE GLOBULINA INSOLUBLE EN FRIO, DURANTE UN TIEMPO SUFICIENTE PARA DESACTIVAR EL VIRUS DE LA HEPATITIS, PERO CONSERVANDO LA ACTIVIDAD DE LA GLOBULINA, EN PRESENCIA DE 10% P/V DE AL MENOS UN ESTABILAZADOR TAL COMO AMINOACIDOS NEUTROS, MONOSACARIDOS, DISACARIDOS Y AZUCAR-ALCOHOLES. ESTA GLOBULINA TIENE APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTICANCEROSA Y ANTILEUCEMICA.
ES509833A 1981-02-25 1982-02-23 "un procedimiento de tratamiento termico para inactivar el virus de hepatitis en una globulina insoluble en frio". Expired ES8303094A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56027448A JPS57140724A (en) 1981-02-25 1981-02-25 Heat-treatment of aqueous solution containing cold insoluble globulin

Publications (2)

Publication Number Publication Date
ES509833A0 ES509833A0 (es) 1983-02-01
ES8303094A1 true ES8303094A1 (es) 1983-02-01

Family

ID=12221394

Family Applications (1)

Application Number Title Priority Date Filing Date
ES509833A Expired ES8303094A1 (es) 1981-02-25 1982-02-23 "un procedimiento de tratamiento termico para inactivar el virus de hepatitis en una globulina insoluble en frio".

Country Status (6)

Country Link
US (1) US4424206A (es)
EP (1) EP0058993B1 (es)
JP (1) JPS57140724A (es)
AT (1) ATE52413T1 (es)
DE (1) DE3280166D1 (es)
ES (1) ES8303094A1 (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2848529A1 (de) * 1978-11-09 1980-05-29 Behringwerke Ag Verfahren zur herstellung des kaelteunloeslichen globulins und dieses enthaltende arzneimittel
US4456590B2 (en) * 1981-11-02 1989-05-30 Heat treatment of lyphilized blood clotting factor viii concentrate
SE446688C (sv) * 1982-09-14 1989-10-16 Magnus Hoeoek Medel foer avlaegsnande av mikroorganismer fraan vaevnader, vilket bestaar av ett protein som kan bindas till mikroorganismerna
JPS5967228A (ja) * 1982-10-07 1984-04-16 Green Cross Corp:The 寒冷不溶性グロブリンの凍結乾燥方法
US4585654A (en) * 1983-04-29 1986-04-29 Armour Pharmaceutical Co. Process for pasteurizing fibronectin
DE3316464A1 (de) * 1983-05-05 1984-11-08 Heinrich Prof Dr Med Liehr Virusantigen, verfahren zu seiner gewinnung und anwendung in diagnose und therapie (impfstoff)
US4820805A (en) * 1983-07-14 1989-04-11 New York Blood Center, Inc. Undenatured virus-free trialkyl phosphate treated biologically active protein derivatives
US4764369A (en) * 1983-07-14 1988-08-16 New York Blood Center Inc. Undenatured virus-free biologically active protein derivatives
US4615886A (en) * 1983-08-31 1986-10-07 The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services Utilizing a halohydrocarbon containing dissolved water to inactivate a lipid virus
JPS6094917A (ja) * 1983-10-28 1985-05-28 Green Cross Corp:The Ｂ型肝炎感染予防用ワクチンの製造方法
AT389815B (de) * 1984-03-09 1990-02-12 Immuno Ag Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern in blutprodukten
JPS61103836A (ja) * 1984-10-24 1986-05-22 Green Cross Corp:The フイブロネクチン製剤
AT385658B (de) * 1985-03-28 1988-05-10 Serotherapeutisches Inst Wien Verfahren zur herstellung einer fuer die anwendung beim menschen geeigneten fibronektinloesung
US4695454A (en) * 1985-04-01 1987-09-22 New York Blood Center, Inc. Process for preparing hepatitis B surface antigen containing particles in novel forms which are highly immunogenic
US5248767A (en) * 1986-06-11 1993-09-28 Behringwerke Aktiengesellschaft Process for the preparation of a pasteurized immunoglobulin preparation using ethanol
DE3619565A1 (de) * 1986-06-11 1987-12-17 Behringwerke Ag Verfahren zur herstellung einer pasteurisierten immunglobulinpraeparation
US4841023A (en) * 1986-06-25 1989-06-20 New York Blood Center, Inc. Inactivation of viruses in labile protein-containing compositions using fatty acids
CA1310267C (en) * 1986-07-09 1992-11-17 Yutaka Hirao Process for heat treating chemically unmodified _-globulin
GB8628104D0 (en) * 1986-11-25 1986-12-31 Connaught Lab Pasteurization of immunoglobin solutions
ES2057191T5 (es) * 1989-01-13 2003-05-01 Mitsubishi Pharma Corp Metodo de produccion para una composicion que contiene proteinas.
USH1509H (en) * 1989-06-09 1995-12-05 Eran; Harutyun Heparin enhanced process for separating antihemophilic factor (Factor VIII) and fibronectin from cryoprecipitate
AU7494491A (en) * 1990-03-06 1991-10-10 Curative Technologies, Inc. Virus free platelet derivatives and method of making same
US5256771A (en) * 1990-04-03 1993-10-26 Miles Inc. Heat treatment of IgM-containing immunoglobulins to eliminate non-specific complement activation
JPH0565233A (ja) * 1991-03-08 1993-03-19 Mitsui Toatsu Chem Inc モノクローナル抗体含有凍結乾燥製剤
DE4125625C2 (de) * 1991-08-02 1999-12-02 Octapharma Ag Glarus Verfahren zur Herstellung von virusinaktivierten Immunglobulinlösungen
US5564345A (en) * 1993-05-11 1996-10-15 Park Ohio Industries Inc. Stackable table, table assembly, and tray and table combination
JP2948708B2 (ja) * 1991-11-27 1999-09-13 ニューヨーク・ブラッド・センター・インコーポレーテッド フィブロネクチン含有点眼液
WO1995031727A1 (en) * 1994-05-13 1995-11-23 Therasorb Medizinische Systeme Gmbh Sterile and pyrogen-free columns coupled to protein for binding and removal of substances from blood
US5762963A (en) * 1995-06-07 1998-06-09 Emory University Method and compositions for controlling oral and pharyngeal pain using capsaicinoids
US6632648B1 (en) 1996-05-14 2003-10-14 Elan Drug Delivery Limited Methods of terminal sterilization of fibrinogen
NL2009407C2 (en) * 2012-09-03 2014-03-04 Dutch Renewable Energy B V Antimicrobial composition.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL30448A (en) * 1967-08-02 1972-06-28 Diagnostic Data Inc Protein metal chelate composition stabilized with saccharide,and preparation thereof
JPS5322139B2 (es) * 1973-11-15 1978-07-06
JPS51118820A (en) * 1975-04-08 1976-10-19 Green Cross Corp:The A process for preparing heat stable macroglobulin
JPS51118819A (en) * 1975-04-08 1976-10-19 Green Cross Corp:The A process for preparing heat stable antitrypsin
JPS5359018A (en) * 1976-11-10 1978-05-27 Green Cross Corp:The Concentrated xiii-th blood coagulating factor derived from human placentaand its preparation
DE2916711A1 (de) * 1979-04-25 1980-11-06 Behringwerke Ag Blutgerinnungsfaktoren und verfahren zu ihrer herstellung
JPS56135418A (en) 1980-03-27 1981-10-22 Green Cross Corp:The Heat treatment of aqueous solution containing 8 factor of coagulation of blood derived from human
JPS5735520A (en) * 1980-08-09 1982-02-26 Green Cross Corp:The Preparation of cold insoluble globulin
US4305871A (en) 1980-09-02 1981-12-15 Edward Shanbrom Method of selectively increasing yield and purity of certain cryoprecipitate proteins by heating

Also Published As

Publication number Publication date
DE3280166D1 (de) 1990-06-13
JPS57140724A (en) 1982-08-31
ES509833A0 (es) 1983-02-01
US4424206A (en) 1984-01-03
EP0058993A2 (en) 1982-09-01
EP0058993A3 (en) 1985-01-23
EP0058993B1 (en) 1990-05-09
ATE52413T1 (de) 1990-05-15
JPH0348169B2 (es) 1991-07-23

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401