ES8302663A1 - Un procedimiento para la preparacion de 3h-2-benzacepinas - Google Patents

Un procedimiento para la preparacion de 3h-2-benzacepinas

Info

Publication number
ES8302663A1
ES8302663A1 ES502211A ES502211A ES8302663A1 ES 8302663 A1 ES8302663 A1 ES 8302663A1 ES 502211 A ES502211 A ES 502211A ES 502211 A ES502211 A ES 502211A ES 8302663 A1 ES8302663 A1 ES 8302663A1
Authority
ES
Spain
Prior art keywords
signifies
hydrogen
see diagramm
general formula
chlorine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES502211A
Other languages
English (en)
Other versions
ES502211A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES8302663A1 publication Critical patent/ES8302663A1/es
Publication of ES502211A0 publication Critical patent/ES502211A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE 3H-2-BENZACEPINAS Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE X ES HIDROGENO, CLORO O BROMO; Y ES HIDROGENO, FLUOR O CLORO; R ES UNO DE VARIOS RADICALES Y N VALE 0 O 1. CONSISTE EN LA SEPARACION DEL GRUPO O GRUPOS FTALOILO DE UN COMPUESTO DE FORMULA (II) O (III), EN LAS QUE X, Y Y N TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), A UNA TEMPERATURA ENTRE LA AMBIENTE Y LA DE REFLUJO DE LA MEZCLA DE REACCION; O BIEN POR REACCION CON UNA MONOALQUILAMINA ACUOSA O HIDRACINA ENTRE 0<025>C Y 60<025>C, SI SE QUIERE OBTENER UNA SAL. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD PSICOTROPICA.
ES502211A 1980-05-16 1981-05-14 Un procedimiento para la preparacion de 3h-2-benzacepinas Granted ES502211A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15050880A 1980-05-16 1980-05-16
US25157981A 1981-04-06 1981-04-06

Publications (2)

Publication Number Publication Date
ES8302663A1 true ES8302663A1 (es) 1983-02-01
ES502211A0 ES502211A0 (es) 1983-02-01

Family

ID=26847744

Family Applications (2)

Application Number Title Priority Date Filing Date
ES502211A Granted ES502211A0 (es) 1980-05-16 1981-05-14 Un procedimiento para la preparacion de 3h-2-benzacepinas
ES510003A Expired ES8304938A1 (es) 1980-05-16 1982-03-01 "un procedimiento para la preparacion de 3h-2-benzacepinas"

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES510003A Expired ES8304938A1 (es) 1980-05-16 1982-03-01 "un procedimiento para la preparacion de 3h-2-benzacepinas"

Country Status (15)

Country Link
EP (1) EP0041627B1 (es)
AR (2) AR228355A1 (es)
AU (1) AU542482B2 (es)
CA (1) CA1157856A (es)
DE (1) DE3165365D1 (es)
DK (1) DK216581A (es)
ES (2) ES502211A0 (es)
FI (1) FI811489L (es)
HU (1) HU184957B (es)
IE (1) IE51286B1 (es)
IL (1) IL62872A (es)
MC (1) MC1388A1 (es)
NO (1) NO811671L (es)
NZ (1) NZ197103A (es)
PT (1) PT73047B (es)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4022800A (en) * 1974-06-03 1977-05-10 Ciba-Geigy Corporation 2-Pyrazolyl-benzophenones
ZA786230B (en) * 1977-12-21 1979-10-31 Smithkline Corp 8 and/or 9 substituted 2-benzazepine compounds
NZ192775A (en) * 1979-02-07 1982-12-07 Hoffmann La Roche Preparation of 1-phenyl-3,4-dihydro-5h-2-benzazepin-5-ones and precursors therein

Also Published As

Publication number Publication date
IE51286B1 (en) 1986-11-26
AR230627A1 (es) 1984-05-31
HU184957B (en) 1984-11-28
AU7063981A (en) 1981-11-19
NO811671L (no) 1981-11-17
DK216581A (da) 1981-11-17
IL62872A0 (en) 1981-07-31
DE3165365D1 (en) 1984-09-13
AU542482B2 (en) 1985-02-21
NZ197103A (en) 1984-07-31
MC1388A1 (fr) 1982-04-27
ES510003A0 (es) 1983-04-01
IL62872A (en) 1984-10-31
ES8304938A1 (es) 1983-04-01
AR228355A1 (es) 1983-02-28
PT73047A (en) 1981-06-01
EP0041627B1 (de) 1984-08-08
EP0041627A2 (de) 1981-12-16
IE811095L (en) 1981-11-16
CA1157856A (en) 1983-11-29
ES502211A0 (es) 1983-02-01
EP0041627A3 (en) 1982-02-24
FI811489L (fi) 1981-11-17
PT73047B (en) 1983-04-29

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