ES8301887A1 - Procedimiento para la obtencion de derivados de ciclopropano - Google Patents
Procedimiento para la obtencion de derivados de ciclopropanoInfo
- Publication number
- ES8301887A1 ES8301887A1 ES502029A ES502029A ES8301887A1 ES 8301887 A1 ES8301887 A1 ES 8301887A1 ES 502029 A ES502029 A ES 502029A ES 502029 A ES502029 A ES 502029A ES 8301887 A1 ES8301887 A1 ES 8301887A1
- Authority
- ES
- Spain
- Prior art keywords
- processes
- production
- pharmaceutical compositions
- compositions containing
- cyclopropane derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/64—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE CICLOPROPANO Y DE SUS SALES DE ADICION DE ACIDO FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE AR ES FENILO SUSTITUIDO O SIN SUSTITUIR; Y R ES HIDROGENO, ALQUILO C <003> O BENCILO. CONSISTE EN LA REACCION DE UN FENOL DE FORMULA AROH O UNA DE SUS SALES CON UNA AMINA DE FORMULA (II), O UNO DE SUS DERIVADOS REACTIVOS, FORMULAS EN LAS QUE X ES CLORO, BROMO, YODO O HIDROXI; Y R Y AR TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE INERTE, A UNA TEMPERATURA ENTRE -20<025>C Y 150<025>C. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SUS EFECTOS SOBRE EL SISTEMA NERVIOSO CENTRAL, COMO ANTIDEPRESIVOS Y ANTICATALEPTICOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19803017812 DE3017812A1 (de) | 1980-05-09 | 1980-05-09 | Cyclopropanderivate, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES502029A0 ES502029A0 (es) | 1983-01-01 |
| ES8301887A1 true ES8301887A1 (es) | 1983-01-01 |
Family
ID=6102013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES502029A Expired ES8301887A1 (es) | 1980-05-09 | 1981-05-08 | Procedimiento para la obtencion de derivados de ciclopropano |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4500541A (es) |
| EP (1) | EP0039771B1 (es) |
| JP (1) | JPS574950A (es) |
| AT (1) | ATE5068T1 (es) |
| AU (1) | AU540658B2 (es) |
| CA (1) | CA1178597A (es) |
| DE (2) | DE3017812A1 (es) |
| ES (1) | ES8301887A1 (es) |
| HU (1) | HU186768B (es) |
| IL (1) | IL62815A (es) |
| ZA (1) | ZA813093B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6030038U (ja) * | 1983-08-08 | 1985-02-28 | アルプス電気株式会社 | 入力装置 |
| US4609758A (en) * | 1985-05-09 | 1986-09-02 | American Home Products Corporation | Phenoxyethylamine derivatives |
| US4956388A (en) * | 1986-12-22 | 1990-09-11 | Eli Lilly And Company | 3-aryloxy-3-substituted propanamines |
| ZA885824B (en) * | 1987-08-14 | 1989-04-26 | Merrell Dow Pharma | Novel antidepressants |
| DK630987D0 (da) * | 1987-12-01 | 1987-12-01 | Ferrosan As | Aryloxyphenylpropylaminer, deres fremstilling og anvendelse |
| US5238959A (en) * | 1988-04-08 | 1993-08-24 | Eli Lilly And Company | 3-phenyloxy-3-phenyl propanamines |
| US5166437A (en) * | 1989-03-03 | 1992-11-24 | Orion-Yhtyma Oy | Process for the preparation of fluoxetine |
| US6291409B1 (en) * | 1998-07-02 | 2001-09-18 | Cargill, Inc. | Process for modifying unsaturated triacylglycerol oils; Resulting products and uses thereof |
| US6051539A (en) * | 1998-07-02 | 2000-04-18 | Cargill, Inc. | Process for modifying unsaturated triacylglycerol oils resulting products and uses thereof |
| US7659225B2 (en) * | 2001-09-17 | 2010-02-09 | Basf Catalysts Llc | Precious metal catalyst for debenzylation |
| US6992037B2 (en) * | 2001-09-17 | 2006-01-31 | Engelhard Corporation | Precious metal catalyst for debenzylation |
| JP2008510775A (ja) | 2004-08-26 | 2008-04-10 | ノイロサーチ アクティーゼルスカブ | モノアミン神経伝達物質再取込み阻害剤としての新規な置換アリールオキシアルキルアミン及びそれらの使用 |
| JP2008510776A (ja) * | 2004-08-26 | 2008-04-10 | ノイロサーチ アクティーゼルスカブ | モノアミン神経伝達物質再取込み阻害剤としての新規な置換ヘテロアリールオキシアルキルアミン及びそれらの使用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT196386B (de) * | 1954-04-08 | 1958-03-10 | Pharmazeutische Fabrik Montavit Gmbh | Verfahren zur Herstellung von am Stickstoff symmetrisch oder unsymmetrisch disubstituierten Aminoalkyläthern aromatisch-aliphatischer Alkohole und deren Salzen |
| GB951461A (en) * | 1959-11-17 | 1964-03-04 | Smith Kline French Lab | Improvements in or relating to substituted 2-phenoxy-cyclopropylamines |
| US3253040A (en) * | 1962-12-10 | 1966-05-24 | Union Carbide Corp | Process for the production of primary 3-hydrocarbyloxypropylamines |
| CH490335A (de) * | 1963-11-05 | 1970-05-15 | Whitefin Holding Sa | Verfahren zur Herstellung von neuen Phenylzyklopropanverbindungen |
| US3928426A (en) * | 1972-01-28 | 1975-12-23 | Robins Co Inc A H | 1-Cyclopropyl-1-phenyl-omega-amino-1-lower alkanoyloxyalkanes |
| US4314081A (en) * | 1974-01-10 | 1982-02-02 | Eli Lilly And Company | Arloxyphenylpropylamines |
| US4207343A (en) * | 1978-06-22 | 1980-06-10 | Eli Lilly And Company | 1-Phenyl-3-(substituted phenoxy)propylamines |
-
1980
- 1980-05-09 DE DE19803017812 patent/DE3017812A1/de not_active Withdrawn
-
1981
- 1981-03-30 DE DE8181102377T patent/DE3161219D1/de not_active Expired
- 1981-03-30 AT AT81102377T patent/ATE5068T1/de not_active IP Right Cessation
- 1981-03-30 EP EP81102377A patent/EP0039771B1/de not_active Expired
- 1981-04-08 AU AU69184/81A patent/AU540658B2/en not_active Ceased
- 1981-05-06 IL IL62815A patent/IL62815A/xx unknown
- 1981-05-07 CA CA000377048A patent/CA1178597A/en not_active Expired
- 1981-05-08 JP JP6839481A patent/JPS574950A/ja active Pending
- 1981-05-08 ES ES502029A patent/ES8301887A1/es not_active Expired
- 1981-05-08 ZA ZA00813093A patent/ZA813093B/xx unknown
- 1981-05-08 HU HU811235A patent/HU186768B/hu unknown
-
1983
- 1983-06-17 US US06/505,558 patent/US4500541A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES502029A0 (es) | 1983-01-01 |
| ZA813093B (en) | 1982-05-26 |
| HU186768B (en) | 1985-09-30 |
| IL62815A0 (en) | 1981-07-31 |
| EP0039771A1 (de) | 1981-11-18 |
| AU540658B2 (en) | 1984-11-29 |
| JPS574950A (en) | 1982-01-11 |
| IL62815A (en) | 1984-08-31 |
| ATE5068T1 (de) | 1983-11-15 |
| US4500541A (en) | 1985-02-19 |
| DE3161219D1 (en) | 1983-11-24 |
| DE3017812A1 (de) | 1981-11-12 |
| EP0039771B1 (de) | 1983-10-19 |
| AU6918481A (en) | 1981-11-12 |
| CA1178597A (en) | 1984-11-27 |
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