ES8207544A1 - Un procedimiento para la preparacion de derivados de macrolidos c-076. - Google Patents

Un procedimiento para la preparacion de derivados de macrolidos c-076.

Info

Publication number
ES8207544A1
ES8207544A1 ES501777A ES501777A ES8207544A1 ES 8207544 A1 ES8207544 A1 ES 8207544A1 ES 501777 A ES501777 A ES 501777A ES 501777 A ES501777 A ES 501777A ES 8207544 A1 ES8207544 A1 ES 8207544A1
Authority
ES
Spain
Prior art keywords
preparation
compounds
acid
dimethylsufoxide
hydroxi
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES501777A
Other languages
English (en)
Spanish (es)
Other versions
ES501777A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES501777A0 publication Critical patent/ES501777A0/es
Publication of ES8207544A1 publication Critical patent/ES8207544A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ES501777A 1980-05-02 1981-04-29 Un procedimiento para la preparacion de derivados de macrolidos c-076. Expired ES8207544A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/146,725 US4289760A (en) 1980-05-02 1980-05-02 23-Keto derivatives of C-076 compounds

Publications (2)

Publication Number Publication Date
ES501777A0 ES501777A0 (es) 1982-09-16
ES8207544A1 true ES8207544A1 (es) 1982-09-16

Family

ID=22518711

Family Applications (1)

Application Number Title Priority Date Filing Date
ES501777A Expired ES8207544A1 (es) 1980-05-02 1981-04-29 Un procedimiento para la preparacion de derivados de macrolidos c-076.

Country Status (13)

Country Link
US (1) US4289760A (forum.php)
EP (1) EP0040913B1 (forum.php)
JP (1) JPS5718684A (forum.php)
AT (1) ATE8637T1 (forum.php)
AU (1) AU547211B2 (forum.php)
CA (1) CA1168605A (forum.php)
DE (1) DE3165016D1 (forum.php)
DK (1) DK193881A (forum.php)
ES (1) ES8207544A1 (forum.php)
GR (1) GR74875B (forum.php)
NZ (1) NZ196897A (forum.php)
PT (1) PT72915B (forum.php)
ZA (1) ZA812908B (forum.php)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57139012A (en) * 1981-02-23 1982-08-27 Sankyo Co Ltd Anthelmintic composition
US4333925A (en) * 1981-05-11 1982-06-08 Merck & Co., Inc. Derivatives of C-076 compounds
US4423209A (en) * 1982-02-26 1983-12-27 Merck & Co., Inc. Processes for the interconversion of avermectin compounds
US4510133A (en) * 1982-04-22 1985-04-09 Imperial Chemical Industries Plc Method for combating pests
US4469682A (en) * 1983-01-28 1984-09-04 Merck & Co., Inc. Avermectin and milbemycin phosphate esters, pharmaceutical compositions, and method of use
US4582852A (en) * 1983-11-02 1986-04-15 Ciba-Geigy Corporation 14- and 15-hydroxy milbemycin derivatives for controlling plant and animal parasites
JPS60126289A (ja) * 1983-11-14 1985-07-05 Sankyo Co Ltd ミルベマイシン類の５−カ−ボネ−ト誘導体
US4579864A (en) * 1984-06-11 1986-04-01 Merck & Co., Inc. Avermectin and milbemycin 13-keto, 13-imino and 13-amino derivatives
US4547491A (en) * 1984-07-18 1985-10-15 Merck & Co., Inc. C-8A-Oxo-avermectin and milbemycin derivatives, pharmaceutical compositions and method of use
GB2168345B (en) * 1984-12-14 1988-05-25 Ciba Geigy Ag Pesticidal 13b-substituted milbemycin derivatives
ES8802229A1 (es) * 1985-04-30 1988-04-16 Glaxo Group Ltd Un procedimiento para preparar nuevos derivados lactonicos macrociclicos.
IT1190285B (it) * 1985-04-30 1988-02-16 Glaxo Group Ltd Antibiotici macrolidi e procedimento per prepararli ed applicarli
US4789684A (en) * 1985-05-02 1988-12-06 Merck & Co., Inc. Anthelmintic fermentation products of microorganisms
ES8605582A1 (es) * 1985-12-11 1986-03-16 Antibioticos Sa Un procedimiento para la preparacion de avermectinas
ES2051731T3 (es) * 1986-01-23 1994-07-01 American Cyanamid Co Un procedimiento para preparar antibioticos macrolidos y su uso.
GB8606108D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Chemical compounds
CH671764A5 (forum.php) * 1986-03-12 1989-09-29 Glaxo Group Ltd
IE62773B1 (en) * 1986-03-12 1995-02-22 American Cyanamid Co Macrolide compounds
CA1296329C (en) * 1986-06-06 1992-02-25 Derek R. Sutherland Macrolide compounds
US4886784A (en) * 1986-09-12 1989-12-12 American Cyanamid Company Novel 23-imino derivatives of 23-keto compounds
US4849446A (en) * 1986-09-12 1989-07-18 American Cyanamid Company 23-imino derivatives of 23-keto compounds
EP0260537A1 (en) * 1986-09-12 1988-03-23 American Cyanamid Company 13-Deoxy-23-oxo(keto) and 23-imino derivatives of 13-deoxy C-076-aglycone compounds
US4916154A (en) * 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
EP0259779B1 (en) * 1986-09-12 1994-08-10 American Cyanamid Company 23-Oxo (Keto) and 23-imino Derivatives of LL-F28249 Compounds
US4877888A (en) * 1986-09-12 1989-10-31 American Cyanamid Company 13-deoxy-23-imino derivatives of 13-deoxy C-076-aglycone compounds
US4886829A (en) * 1987-03-06 1989-12-12 American Cyanamid Company 23-Oxo (keto) and 23-imino derivatives of mono- and diepoxy LL-F28249 compounds
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives
US4906619A (en) * 1988-07-22 1990-03-06 Merck & Co., Inc. Alkyl avermectin derivatives
US5428034A (en) * 1988-09-02 1995-06-27 Sankyo Co., Ltd. Milbemycin derivatives, their preparation and their use
US5830875A (en) * 1989-10-30 1998-11-03 Merck & Co., Inc. 24-and 25-substituted avermectin and milbemycin derivatives
JP2622197B2 (ja) * 1990-03-01 1997-06-18 三共株式会社 １３−エーテル置換ミルベマイシン誘導体
US5169839A (en) * 1990-05-11 1992-12-08 Merck & Co., Inc. Derivatives of 3'- and 3"-o-desmethyl avermectin compounds, compositions and methods of treating melmintic and parasitic infections
US5188944A (en) * 1990-06-22 1993-02-23 Merck & Co., Inc. Process for the glycosylation of avermectin agylcones
US5208222A (en) * 1991-03-28 1993-05-04 Merck & Co., Inc. 4"-and 4'-alkylthio avermectin derivatives
US5240915A (en) * 1991-10-15 1993-08-31 Merck & Co., Inc. Avermectin derivatives
CA2085703C (en) * 1991-12-18 2001-05-01 Toshiaki Yanai 13-(substituted thio) acetoxymilbemycin derivatives, their preparation and their agrochemical uses
US5229415A (en) * 1992-03-24 1993-07-20 Merck & Co., Inc. Alkylthio alkyl avermectins are active antiparasitic agents
IL107810A0 (en) * 1992-12-17 1994-02-27 Exxon Chemical Patents Inc Functionalized polymers and processes for the preparation thereof
DK0765879T3 (da) * 1995-09-29 2001-03-19 Sankyo Co 13-substituerede milbemycin 5-oximderivater, deres fremstilling og deres anvendelse over for insekter og andre skadedyr
DK1276748T3 (da) 2000-04-27 2006-03-20 Sankyo Lifetech Company Ltd 13-substituerede milbemycinderivater, deres fremstilling og deres anvendelse over for insekter og andre skadedyr

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4134973A (en) * 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
US4201861A (en) * 1977-10-03 1980-05-06 Merck & Co., Inc. Acyl derivatives of C-076 compounds
NZ188459A (en) * 1977-10-03 1982-09-07 Merck & Co Inc Derivatives of c-076 compounds and pesticidal compositions
US4172940A (en) * 1977-10-03 1979-10-30 Merck & Co., Inc. Purification of C-076 compounds by single column chromatography
US4199569A (en) * 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
US4206205A (en) * 1977-10-03 1980-06-03 Merck & Co., Inc. Monosaccharide and aglycone derivatives of C-076
US4171314A (en) * 1977-12-19 1979-10-16 Merck & Co., Inc. 13-Halo and 13-deoxy C-076 compounds
IL56149A (en) * 1977-12-19 1989-09-28 Merck & Co Inc 13-halo and 13-deoxy derivatives of c-076 compounds,their preparation and method for the treatment of parasitic infections in animals therewith
US4203976A (en) * 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
US4200581A (en) * 1978-08-04 1980-04-29 Merck & Co., Inc. Alkyl derivatives of C-076 compounds

Also Published As

Publication number Publication date
AU547211B2 (en) 1985-10-10
NZ196897A (en) 1984-09-28
JPS5718684A (en) 1982-01-30
DK193881A (da) 1981-11-03
EP0040913A1 (en) 1981-12-02
DE3165016D1 (en) 1984-08-30
US4289760A (en) 1981-09-15
AU6973081A (en) 1981-11-05
GR74875B (forum.php) 1984-07-12
ES501777A0 (es) 1982-09-16
ATE8637T1 (de) 1984-08-15
JPH0254358B2 (forum.php) 1990-11-21
PT72915B (en) 1983-02-16
CA1168605A (en) 1984-06-05
PT72915A (en) 1981-05-01
EP0040913B1 (en) 1984-07-25
ZA812908B (en) 1982-12-29

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000403