PT72915B - Process for preparing 23-keto derivatives of c-076 coumpounds - Google Patents

Process for preparing 23-keto derivatives of c-076 coumpounds

Info

Publication number
PT72915B
PT72915B PT72915A PT7291581A PT72915B PT 72915 B PT72915 B PT 72915B PT 72915 A PT72915 A PT 72915A PT 7291581 A PT7291581 A PT 7291581A PT 72915 B PT72915 B PT 72915B
Authority
PT
Portugal
Prior art keywords
compounds
chromic acid
derivatives
keto
oxidized
Prior art date
Application number
PT72915A
Other languages
English (en)
Other versions
PT72915A (en
Inventor
Helmut H Mrozik
John G Macconnell
August J Kemp
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PT72915A publication Critical patent/PT72915A/pt
Publication of PT72915B publication Critical patent/PT72915B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Veterinary Medicine (AREA)
  • Dentistry (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PT72915A 1980-05-02 1981-04-24 Process for preparing 23-keto derivatives of c-076 coumpounds PT72915B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/146,725 US4289760A (en) 1980-05-02 1980-05-02 23-Keto derivatives of C-076 compounds

Publications (2)

Publication Number Publication Date
PT72915A PT72915A (en) 1981-05-01
PT72915B true PT72915B (en) 1983-02-16

Family

ID=22518711

Family Applications (1)

Application Number Title Priority Date Filing Date
PT72915A PT72915B (en) 1980-05-02 1981-04-24 Process for preparing 23-keto derivatives of c-076 coumpounds

Country Status (13)

Country Link
US (1) US4289760A (pt)
EP (1) EP0040913B1 (pt)
JP (1) JPS5718684A (pt)
AT (1) ATE8637T1 (pt)
AU (1) AU547211B2 (pt)
CA (1) CA1168605A (pt)
DE (1) DE3165016D1 (pt)
DK (1) DK193881A (pt)
ES (1) ES8207544A1 (pt)
GR (1) GR74875B (pt)
NZ (1) NZ196897A (pt)
PT (1) PT72915B (pt)
ZA (1) ZA812908B (pt)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57139012A (en) * 1981-02-23 1982-08-27 Sankyo Co Ltd Anthelmintic composition
US4333925A (en) * 1981-05-11 1982-06-08 Merck & Co., Inc. Derivatives of C-076 compounds
US4423209A (en) * 1982-02-26 1983-12-27 Merck & Co., Inc. Processes for the interconversion of avermectin compounds
US4510133A (en) * 1982-04-22 1985-04-09 Imperial Chemical Industries Plc Method for combating pests
US4469682A (en) * 1983-01-28 1984-09-04 Merck & Co., Inc. Avermectin and milbemycin phosphate esters, pharmaceutical compositions, and method of use
US4582852A (en) * 1983-11-02 1986-04-15 Ciba-Geigy Corporation 14- and 15-hydroxy milbemycin derivatives for controlling plant and animal parasites
JPS60126289A (ja) * 1983-11-14 1985-07-05 Sankyo Co Ltd ミルベマイシン類の５−カ−ボネ−ト誘導体
US4579864A (en) * 1984-06-11 1986-04-01 Merck & Co., Inc. Avermectin and milbemycin 13-keto, 13-imino and 13-amino derivatives
US4547491A (en) * 1984-07-18 1985-10-15 Merck & Co., Inc. C-8A-Oxo-avermectin and milbemycin derivatives, pharmaceutical compositions and method of use
GB2168345B (en) * 1984-12-14 1988-05-25 Ciba Geigy Ag Pesticidal 13b-substituted milbemycin derivatives
GR861146B (en) * 1985-04-30 1986-08-14 American Cyanamid Co Chemical compounds
IL78621A (en) * 1985-04-30 1991-06-30 American Cyanamid Co Mylbemycin analogs,their preparation and pesticidal compositions containing them
US4789684A (en) * 1985-05-02 1988-12-06 Merck & Co., Inc. Anthelmintic fermentation products of microorganisms
ES8605582A1 (es) * 1985-12-11 1986-03-16 Antibioticos Sa Un procedimiento para la preparacion de avermectinas
JPH0774219B2 (ja) * 1986-01-23 1995-08-09 アメリカン・サイアナミツド・カンパニー マクロライド抗生物質
GB8606108D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Chemical compounds
ES2061487T3 (es) * 1986-03-12 1994-12-16 American Cyanamid Co Compuestos macrolidos.
NL8700581A (nl) * 1986-03-12 1987-10-01 Glaxo Group Ltd Antibioticum, preparaat dat dat bevat, werkwijze voor de bereiding daarvan, werkwijze voor het bestrijden van plagen en nieuwe streptomyces-mutant.
CA1296329C (en) * 1986-06-06 1992-02-25 Derek R. Sutherland Macrolide compounds
EP0260537A1 (en) * 1986-09-12 1988-03-23 American Cyanamid Company 13-Deoxy-23-oxo(keto) and 23-imino derivatives of 13-deoxy C-076-aglycone compounds
US4849446A (en) * 1986-09-12 1989-07-18 American Cyanamid Company 23-imino derivatives of 23-keto compounds
US4886784A (en) * 1986-09-12 1989-12-12 American Cyanamid Company Novel 23-imino derivatives of 23-keto compounds
US4916154A (en) * 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
ES2058082T3 (es) * 1986-09-12 1994-11-01 American Cyanamid Co Derivados 23-oxo (ceto) y 23-imino de compuestos ll-f28249.
US4877888A (en) * 1986-09-12 1989-10-31 American Cyanamid Company 13-deoxy-23-imino derivatives of 13-deoxy C-076-aglycone compounds
US4886829A (en) * 1987-03-06 1989-12-12 American Cyanamid Company 23-Oxo (keto) and 23-imino derivatives of mono- and diepoxy LL-F28249 compounds
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives
US4906619A (en) * 1988-07-22 1990-03-06 Merck & Co., Inc. Alkyl avermectin derivatives
US5428034A (en) * 1988-09-02 1995-06-27 Sankyo Co., Ltd. Milbemycin derivatives, their preparation and their use
US5830875A (en) * 1989-10-30 1998-11-03 Merck & Co., Inc. 24-and 25-substituted avermectin and milbemycin derivatives
JP2622197B2 (ja) * 1990-03-01 1997-06-18 三共株式会社 １３−エーテル置換ミルベマイシン誘導体
US5169839A (en) * 1990-05-11 1992-12-08 Merck & Co., Inc. Derivatives of 3'- and 3"-o-desmethyl avermectin compounds, compositions and methods of treating melmintic and parasitic infections
US5188944A (en) * 1990-06-22 1993-02-23 Merck & Co., Inc. Process for the glycosylation of avermectin agylcones
US5208222A (en) * 1991-03-28 1993-05-04 Merck & Co., Inc. 4"-and 4'-alkylthio avermectin derivatives
US5240915A (en) * 1991-10-15 1993-08-31 Merck & Co., Inc. Avermectin derivatives
US5276033A (en) * 1991-12-18 1994-01-04 Sankyo Company, Limited 13-(substituted thio)acetoxymilbemycin derivatives, their preparation and their agrochemical uses
US5229415A (en) * 1992-03-24 1993-07-20 Merck & Co., Inc. Alkylthio alkyl avermectins are active antiparasitic agents
IL107810A0 (en) * 1992-12-17 1994-02-27 Exxon Chemical Patents Inc Functionalized polymers and processes for the preparation thereof
CZ288178B6 (en) * 1995-09-29 2001-05-16 Sankyo Co Milbemycin-5-oxime derivatives substituted in position 13-, and their use
MXPA02010587A (es) 2000-04-27 2003-03-10 Sankyo Co Derivados de milbemicina 13-sustituidos, su preparacion y su uso contra insectos y otras plagas.

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4134973A (en) * 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
US4199569A (en) * 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
NZ188459A (en) * 1977-10-03 1982-09-07 Merck & Co Inc Derivatives of c-076 compounds and pesticidal compositions
US4206205A (en) * 1977-10-03 1980-06-03 Merck & Co., Inc. Monosaccharide and aglycone derivatives of C-076
US4172940A (en) * 1977-10-03 1979-10-30 Merck & Co., Inc. Purification of C-076 compounds by single column chromatography
US4201861A (en) * 1977-10-03 1980-05-06 Merck & Co., Inc. Acyl derivatives of C-076 compounds
IL56149A (en) * 1977-12-19 1989-09-28 Merck & Co Inc 13-halo and 13-deoxy derivatives of c-076 compounds,their preparation and method for the treatment of parasitic infections in animals therewith
US4171314A (en) * 1977-12-19 1979-10-16 Merck & Co., Inc. 13-Halo and 13-deoxy C-076 compounds
US4203976A (en) * 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
US4200581A (en) * 1978-08-04 1980-04-29 Merck & Co., Inc. Alkyl derivatives of C-076 compounds

Also Published As

Publication number Publication date
JPS5718684A (en) 1982-01-30
ES501777A0 (es) 1982-09-16
EP0040913B1 (en) 1984-07-25
DK193881A (da) 1981-11-03
AU547211B2 (en) 1985-10-10
ES8207544A1 (es) 1982-09-16
NZ196897A (en) 1984-09-28
CA1168605A (en) 1984-06-05
ATE8637T1 (de) 1984-08-15
GR74875B (pt) 1984-07-12
JPH0254358B2 (pt) 1990-11-21
US4289760A (en) 1981-09-15
AU6973081A (en) 1981-11-05
ZA812908B (en) 1982-12-29
EP0040913A1 (en) 1981-12-02
PT72915A (en) 1981-05-01
DE3165016D1 (en) 1984-08-30

Similar Documents

Publication Publication Date Title
PT72915B (en) Process for preparing 23-keto derivatives of c-076 coumpounds
AU592858B2 (en) Macrolide compounds their preparation and their use
IE781963L (en) C-076 compounds.
ES8301945A1 (es) Un procedimiento para la preparacion de piridin- y pira- cin-derivados
ZW1488A1 (en) A composition for application to a soil or plant locus(an additive for agricultural chemical compositions)
EP0303933A2 (de) Neue Avermectin Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
EP0189377A3 (en) An agricultural composition with reduced toxicity to fishes and shellfishes
SG46464A1 (en) Biocidal composition
JPH0417922B2 (pt)
ES8305357A1 (es) "un procedimiento para la preparacion de derivados de piridina".
IL44447A (en) N-phenyl-tricyclo(4,2,2,02,4)nonane(or nonene)-6,7-dicarboximides their preparation and their use as insecticides
IE43006L (en) Bactericidal and fungicidal agents.
JPS5746974A (en) Alpha- or beta-substituted-gamma-phenylthio-gamma-butyrolactone and its preparation
ES420304A1 (es) Un procedimiento para la preparacion de una composicion a- gricola.
JPH0465043B2 (pt)
JPS542322A (en) Alkyl n-acylanthranylate derivatives, their preparation, and agricultural and horticultural fungicide containing the same
JPS57136572A (en) Novel pyrazoline derivative, its preparation, and noxious life controlling agent containing said derivative as active component
ES481059A1 (es) Procedimiento para la preparacion de compuestos fenilen- o ciclohexilen-bis (2-propinilicos).
JPS5513232A (en) Antibacterial agent for agriculture and horticulture
JPS55149278A (en) Preparation of sesquiterpene derivative compound
FR2451161A1 (fr) Melanges synergiques a base d'esters de (s) allethrolone et de (r) allethrolone, doues d'activite contre les arthropodes
IE822504L (en) Pyrimidine derivative.
TH1198B (th) อนุพันธุ์ของไพรีดินและไพราซีน
JPS56147798A (en) Tylosin derivative
JPS553733A (en) Phenazine derivative inhibiting phosphodiesterase and its preparation by microorganism