ES8205790A1 - Un procedimiento para la preparacion de derivados de imadazol n- sustituidos, o su sales de adicion de acido. - Google Patents

Un procedimiento para la preparacion de derivados de imadazol n- sustituidos, o su sales de adicion de acido.

Info

Publication number
ES8205790A1
ES8205790A1 ES497467A ES497467A ES8205790A1 ES 8205790 A1 ES8205790 A1 ES 8205790A1 ES 497467 A ES497467 A ES 497467A ES 497467 A ES497467 A ES 497467A ES 8205790 A1 ES8205790 A1 ES 8205790A1
Authority
ES
Spain
Prior art keywords
compositions
substituted imidazole
preparing
phenyl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES497467A
Other languages
English (en)
Other versions
ES497467A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Publication of ES8205790A1 publication Critical patent/ES8205790A1/es
Publication of ES497467A0 publication Critical patent/ES497467A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE IMIDAZOL N-SUSTITUIDOS Y DE SUS SALES DE ADICION DE ACIDO, DE FORMULA (I), EN LA QUE R Y R'' PUEDEN SER FENILO Y OPCIONALMENTE SUSTITUIDO. CONSISTE EN LA REACCION DE IMIDAZOL O UNO DE SUS DERIVADOS DE FORMULA (II), CON UN ALDEHIDO DE FORMULA (III), EN LAS QUE A ES HIDROGENO, TRIALQUILESTAÑO O TRIMETILSILILO; Z ES UN ATOMO DE HALOGENO Y R Y R'' SON LOS MISMOS QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO INERTE, A UNA TEMPERATURA ENTRE 0 C Y LA DE EBULLICION DEL DISOLVENTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO AGENTES ANTIFUNGICOS.
ES497467A 1979-12-05 1980-12-04 Un procedimiento para la preparacion de derivados de imadazol n- sustituidos, o su sales de adicion de acido. Granted ES497467A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15858179A JPS5692887A (en) 1979-12-05 1979-12-05 N-substituted imidazole derivative

Publications (2)

Publication Number Publication Date
ES8205790A1 true ES8205790A1 (es) 1982-08-01
ES497467A0 ES497467A0 (es) 1982-08-01

Family

ID=15674808

Family Applications (1)

Application Number Title Priority Date Filing Date
ES497467A Granted ES497467A0 (es) 1979-12-05 1980-12-04 Un procedimiento para la preparacion de derivados de imadazol n- sustituidos, o su sales de adicion de acido.

Country Status (10)

Country Link
US (1) US4288448A (es)
EP (1) EP0030371B1 (es)
JP (1) JPS5692887A (es)
AT (1) ATE4982T1 (es)
AU (1) AU535592B2 (es)
CA (1) CA1154445A (es)
DE (1) DE3065325D1 (es)
DK (1) DK519680A (es)
ES (1) ES497467A0 (es)
HU (1) HU185225B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008148851A1 (en) 2007-06-08 2008-12-11 Janssen Pharmaceutica N.V. Piperidine/piperazine derivatives
JO2972B1 (en) 2007-06-08 2016-03-15 جانسين فارماسوتيكا ان. في Piperidine / piperazine derivatives
WO2008148868A1 (en) 2007-06-08 2008-12-11 Janssen Pharmaceutica N.V. Piperidine/piperazine derivatives
WO2008148840A1 (en) 2007-06-08 2008-12-11 Janssen Pharmaceutica N.V. Piperidine/piperazine derivatives
JP5579170B2 (ja) 2008-06-05 2014-08-27 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ Ｄｇａｔ阻害剤とｐｐａｒ作動薬を含有する薬剤組み合わせ物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3435049A (en) * 1965-05-19 1969-03-25 Hoffmann La Roche Nitroimidazole derivatives
US3468902A (en) * 1966-06-10 1969-09-23 Hoffmann La Roche 1-substituted-2-nitroimidazole derivatives
GB1170188A (en) * 1967-09-15 1969-11-12 Bayer Ag N-trityl-imidazoles and salts and uses thereof
SU461926A1 (ru) * 1973-07-06 1975-02-28 Московский Ордена Ленина И Ордена Трудового Красного Знамени Химико-Технологический Институт Им.Д.И. Менделеева Способ получени -глицидилимидазола

Also Published As

Publication number Publication date
AU6473180A (en) 1981-06-11
ATE4982T1 (de) 1983-10-15
DE3065325D1 (en) 1983-11-17
CA1154445A (en) 1983-09-27
AU535592B2 (en) 1984-03-29
JPS5692887A (en) 1981-07-27
US4288448A (en) 1981-09-08
EP0030371B1 (en) 1983-10-12
ES497467A0 (es) 1982-08-01
EP0030371A1 (en) 1981-06-17
DK519680A (da) 1981-06-06
HU185225B (en) 1984-12-28

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