ES8205790A1 - N-substituted imidazole derivatives, a process for their preparation, antifungal compositions comprising them and their use for preparing such compositions. - Google Patents

N-substituted imidazole derivatives, a process for their preparation, antifungal compositions comprising them and their use for preparing such compositions.

Info

Publication number
ES8205790A1
ES8205790A1 ES497467A ES497467A ES8205790A1 ES 8205790 A1 ES8205790 A1 ES 8205790A1 ES 497467 A ES497467 A ES 497467A ES 497467 A ES497467 A ES 497467A ES 8205790 A1 ES8205790 A1 ES 8205790A1
Authority
ES
Spain
Prior art keywords
compositions
substituted imidazole
preparing
phenyl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES497467A
Other languages
Spanish (es)
Other versions
ES497467A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Publication of ES497467A0 publication Critical patent/ES497467A0/en
Publication of ES8205790A1 publication Critical patent/ES8205790A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

An N-substituted imidazole compound of the formula: < IMAGE > wherein R and R' are independently a phenyl group optionally substituted with one or more halogen, C1-C8 alkyl, C1-C8 alkoxy, C1-C8 alkylthio, phenyl, phenoxy, phenylthio, hydroxyl, trifluoromethyl, amino, carbamoyl, di(C1-C8) alkylamino, C1-C8 alkanoylamino, nitro, cyano, carboxy, C1-C8 alkoxycarbonyl, C1-C8 alkylsulfonyloxy or C1-C8 alkanoylpiperazino groups a C1-C15 alkyl group or a phenyl (C1-C2) alkyl group optionally bearing halogen on the benzene ring, and its acid-addition salts, which is useful as an antifungal agent.
ES497467A 1979-12-05 1980-12-04 N-substituted imidazole derivatives, a process for their preparation, antifungal compositions comprising them and their use for preparing such compositions. Expired ES8205790A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15858179A JPS5692887A (en) 1979-12-05 1979-12-05 N-substituted imidazole derivative

Publications (2)

Publication Number Publication Date
ES497467A0 ES497467A0 (en) 1982-08-01
ES8205790A1 true ES8205790A1 (en) 1982-08-01

Family

ID=15674808

Family Applications (1)

Application Number Title Priority Date Filing Date
ES497467A Expired ES8205790A1 (en) 1979-12-05 1980-12-04 N-substituted imidazole derivatives, a process for their preparation, antifungal compositions comprising them and their use for preparing such compositions.

Country Status (10)

Country Link
US (1) US4288448A (en)
EP (1) EP0030371B1 (en)
JP (1) JPS5692887A (en)
AT (1) ATE4982T1 (en)
AU (1) AU535592B2 (en)
CA (1) CA1154445A (en)
DE (1) DE3065325D1 (en)
DK (1) DK519680A (en)
ES (1) ES8205790A1 (en)
HU (1) HU185225B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO2972B1 (en) 2007-06-08 2016-03-15 جانسين فارماسوتيكا ان. في Piperidine/Piperazine derivatives
BRPI0813331A2 (en) 2007-06-08 2014-12-23 Janssen Pharmaceutica Nv PIPERIDINE / PIPERAZINE Derivatives
ES2558152T3 (en) 2007-06-08 2016-02-02 Janssen Pharmaceutica, N.V. Piperidine / Piperazine Derivatives
ES2483898T3 (en) 2007-06-08 2014-08-08 Janssen Pharmaceutica, N.V. Piperidine / Piperazine Derivatives
PE20140572A1 (en) 2008-06-05 2014-05-16 Janssen Pharmaceutica Nv DRUG COMBINATIONS INCLUDING A DGAT INHIBITOR AND A PPAR AGONIST

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3435049A (en) * 1965-05-19 1969-03-25 Hoffmann La Roche Nitroimidazole derivatives
US3468902A (en) * 1966-06-10 1969-09-23 Hoffmann La Roche 1-substituted-2-nitroimidazole derivatives
GB1170188A (en) * 1967-09-15 1969-11-12 Bayer Ag N-trityl-imidazoles and salts and uses thereof
SU461926A1 (en) * 1973-07-06 1975-02-28 Московский Ордена Ленина И Ордена Трудового Красного Знамени Химико-Технологический Институт Им.Д.И. Менделеева The method of obtaining -glycidylimidazole

Also Published As

Publication number Publication date
US4288448A (en) 1981-09-08
ES497467A0 (en) 1982-08-01
JPS5692887A (en) 1981-07-27
CA1154445A (en) 1983-09-27
HU185225B (en) 1984-12-28
EP0030371A1 (en) 1981-06-17
DK519680A (en) 1981-06-06
DE3065325D1 (en) 1983-11-17
ATE4982T1 (en) 1983-10-15
AU6473180A (en) 1981-06-11
EP0030371B1 (en) 1983-10-12
AU535592B2 (en) 1984-03-29

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