ES8205211A1 - Procedure for obtaining a heterociclic primary amine derivative (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for obtaining a heterociclic primary amine derivative (Machine-translation by Google Translate, not legally binding)

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Publication number
ES8205211A1
ES8205211A1 ES497514A ES497514A ES8205211A1 ES 8205211 A1 ES8205211 A1 ES 8205211A1 ES 497514 A ES497514 A ES 497514A ES 497514 A ES497514 A ES 497514A ES 8205211 A1 ES8205211 A1 ES 8205211A1
Authority
ES
Spain
Prior art keywords
methyl
obtaining
furanil
heterociclic
metil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES497514A
Other languages
Spanish (es)
Other versions
ES497514A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Liade SA
Original Assignee
Laboratorios Liade SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Liade SA filed Critical Laboratorios Liade SA
Priority to ES497514A priority Critical patent/ES497514A0/en
Publication of ES8205211A1 publication Critical patent/ES8205211A1/en
Publication of ES497514A0 publication Critical patent/ES497514A0/en
Granted legal-status Critical Current

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  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Process for obtaining a heterociclic primary amine derivative of N- (2 - (((5- (dimethylamino) -metil-2-furanil) methyl) thyroid) ethyl) n "- methyl-2-nitro-1, 1-etenodyamine and its physiologically acceptable salts. Understand the following stages: first, react 5 (dimethylamine) methyl-2-furanil methanol with thiourea in the presence of chlorhydric acid, obtaining the corresponding tiol; second, the mentioned tiol by reaction with ethylamine is transformed into 2 (((5- (dimethylamino) methyl-2-furanil) methyl-2-furanil) -metil) -tio) etenamine; third, molool reaction, the synthetized compound in the second stage with 1,1-bis (methyl tio) -2-nitroetane, obtaining the N- (2 (((5- (dimethylamine) methyl-2- furanil) -metil) tio) etil) -1, methyltho-2-nitroetenamine; fourth, the composite of the third stage is an excess of methylamine in an absolute ethanol solution, obtaining the product searched, and finally, the product of the fourth stage, optionally, the physiologically acceptable salts are obtained, dissolving in ethanol and trying it with a mineral or organic acid. For use as inhibitors of gastric secretion. (Machine-translation by Google Translate, not legally binding)
ES497514A 1980-12-05 1980-12-05 PROCEDURE FOR OBTAINING A HETEROCICLICAL PRIMARY AMINE DERIVATIVE Granted ES497514A0 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES497514A ES497514A0 (en) 1980-12-05 1980-12-05 PROCEDURE FOR OBTAINING A HETEROCICLICAL PRIMARY AMINE DERIVATIVE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES497514A ES497514A0 (en) 1980-12-05 1980-12-05 PROCEDURE FOR OBTAINING A HETEROCICLICAL PRIMARY AMINE DERIVATIVE

Publications (2)

Publication Number Publication Date
ES8205211A1 true ES8205211A1 (en) 1981-10-16
ES497514A0 ES497514A0 (en) 1981-10-16

Family

ID=8481519

Family Applications (1)

Application Number Title Priority Date Filing Date
ES497514A Granted ES497514A0 (en) 1980-12-05 1980-12-05 PROCEDURE FOR OBTAINING A HETEROCICLICAL PRIMARY AMINE DERIVATIVE

Country Status (1)

Country Link
ES (1) ES497514A0 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT387573B (en) * 1984-05-02 1989-02-10 Richter Gedeon Vegyeszet METHOD FOR PRODUCING THE BASIC THIOAETHER 2 - ((2-AMINO-AETHYL) -THIOMETHYL) -5 (DIMETHYL-AMINOMETHYL) -FURANE AND THE ACID ADDITION SALTS THEREOF
AT391470B (en) * 1985-01-11 1990-10-10 Richter Gedeon Vegyeszet METHOD FOR PRODUCING 1- (2- (5HU850111104 / 85

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT387573B (en) * 1984-05-02 1989-02-10 Richter Gedeon Vegyeszet METHOD FOR PRODUCING THE BASIC THIOAETHER 2 - ((2-AMINO-AETHYL) -THIOMETHYL) -5 (DIMETHYL-AMINOMETHYL) -FURANE AND THE ACID ADDITION SALTS THEREOF
AT391470B (en) * 1985-01-11 1990-10-10 Richter Gedeon Vegyeszet METHOD FOR PRODUCING 1- (2- (5HU850111104 / 85

Also Published As

Publication number Publication date
ES497514A0 (en) 1981-10-16

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