ES392093A1 - 2-amino-5-chloro-thiazole derivatives - Google Patents

2-amino-5-chloro-thiazole derivatives

Info

Publication number
ES392093A1
ES392093A1 ES392093A ES392093A ES392093A1 ES 392093 A1 ES392093 A1 ES 392093A1 ES 392093 A ES392093 A ES 392093A ES 392093 A ES392093 A ES 392093A ES 392093 A1 ES392093 A1 ES 392093A1
Authority
ES
Spain
Prior art keywords
chloro
amino
thiazole
heterocyclic
amine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES392093A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Melle Bezons SA
Original Assignee
Melle Bezons SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Melle Bezons SA filed Critical Melle Bezons SA
Publication of ES392093A1 publication Critical patent/ES392093A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof

Abstract

Process for the preparation of derivatives of amino-2 chloro-5 thiazole, which have in particular sedative, tranquilizing, analgesic and especially anti-inflammatory properties, characterized in that chloroacetamido-2 chloro-5 thiazole is reacted with an amine of the formula (see formula) in which R and R', which may be the same or different from each other, each represent hydrogen or an alkyl, aralkyl, heterocyclic or (heterocyclic) alkyl group, or also R and R' represent the two extremities of the same cycle that closes on the nitrogen atom of the amine, thus constituting a nitrogenous heterocycle. (Machine-translation by Google Translate, not legally binding)
ES392093A 1970-06-11 1971-06-09 2-amino-5-chloro-thiazole derivatives Expired ES392093A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7021383A FR2092714B1 (en) 1970-06-11 1970-06-11

Publications (1)

Publication Number Publication Date
ES392093A1 true ES392093A1 (en) 1974-10-01

Family

ID=9056998

Family Applications (2)

Application Number Title Priority Date Filing Date
ES392094A Expired ES392094A1 (en) 1970-06-11 1971-06-09 2-amino-5-chloro-thiazole derivatives
ES392093A Expired ES392093A1 (en) 1970-06-11 1971-06-09 2-amino-5-chloro-thiazole derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES392094A Expired ES392094A1 (en) 1970-06-11 1971-06-09 2-amino-5-chloro-thiazole derivatives

Country Status (5)

Country Link
JP (1) JPS504664B1 (en)
DE (1) DE2128941A1 (en)
ES (2) ES392094A1 (en)
FR (1) FR2092714B1 (en)
GB (1) GB1355718A (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS548367U (en) * 1977-06-20 1979-01-19
JPS5447361U (en) * 1977-09-08 1979-04-02
US4217355A (en) * 1978-04-24 1980-08-12 Pfizer Inc. Amide therapeutic agents
FR2572074B1 (en) * 1984-10-18 1987-07-17 Sanofi Sa THIADIAZOLE DERIVATIVES ACTIVE IN THE CENTRAL NERVOUS SYSTEM, PROCESS FOR OBTAINING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2612187B1 (en) * 1987-03-12 1989-07-21 Sanofi Sa THIAZOLE DERIVATIVES ACTIVE IN THE CHOLINERGIC SYSTEM, THEIR PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
FR2618780B1 (en) * 1987-07-29 1989-12-08 Irceba THIAZOLE DERIVATIVES BELONGING TO THE FAMILY OF 2-PIPERAZINOACETAMIDO-4-METHYLTHIAZOLES, METHOD OF PREPARATION AND THERAPEUTIC USE
GB9823871D0 (en) * 1998-10-30 1998-12-23 Pharmacia & Upjohn Spa 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents
EP1558253A4 (en) * 2002-10-30 2007-07-25 Merck & Co Inc Piperidinyl-alpha-aminoamide modulators of chemokine receptor activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR7428A (en) *

Also Published As

Publication number Publication date
GB1355718A (en) 1974-06-05
DE2128941A1 (en) 1971-12-16
FR2092714B1 (en) 1974-03-22
JPS504664B1 (en) 1975-02-22
FR2092714A1 (en) 1972-01-28
ES392094A1 (en) 1974-08-01

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