ES345365A1 - A procedure for the preparation of new derivatives of 1-phenyl-2-aminoetanol. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the preparation of new derivatives of 1-phenyl-2-aminoetanol. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES345365A1 ES345365A1 ES0345365A ES345365A ES345365A1 ES 345365 A1 ES345365 A1 ES 345365A1 ES 0345365 A ES0345365 A ES 0345365A ES 345365 A ES345365 A ES 345365A ES 345365 A1 ES345365 A1 ES 345365A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- straight
- carbon atoms
- formula
- hydrogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
A procedure for the preparation of new derivatives of 1-phenyl-2-aminoethanol, which consists in reducing the carbonyl group to an alcoholic group **(See formula)** of a ketone that responds to the general formula above, where R1 represents a hydrogen atom or a straight or branched chain alkyl radical, containing from 1 to 6 carbon atoms; R2 represents a hydrogen atom or a benzyl group; R3 represents a hydrogen atom or a straight or branched chain alkyl radical, containing from 1 to 6 carbon atoms, the radical of which may be substituted with hydroxyl groups, amino groups or heterocyclic rings containing one or more heteroatoms, for example morpholine, or represents a cycloalkyl, aralkyl or aryloxyalkyl radical which may be optionally substituted with one or more alkoxy or hydroxyl groups, for example; X represents a hydroxyalkyl or hydroxyaralkyl radical with a straight or branched alkyl chain containing 1 to 6 carbon atoms, a carboxyl radical or an alkoxycarbonyl radical of the formula -COOR4 (where R4 represents a straight or branched chain alkyl radical containing 1 to 6 carbon atoms), either represents a radical of the formula -CONHOH or -COnHnH2 or an amido radical of the formula -CONR5R6 (where R5 and R6, which may be the same or different, each represent a hydrogen atom, an aralkyl radical or a straight or branched chain alkyl radical containing 1 to 6 carbon atoms, which may be substituted with hydroxyl or amino groups, or where R5 and R6 together with the adjacent nitrogen atom forms a heterocyclic ring which may contain additional heteroatoms) or are groups convertible into those, if desired by protecting the phenolic hydroxyl group, isolating the desired product as an addition salt with acids, physiological strongly acceptable. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES0345365A ES345365A1 (en) | 1967-09-22 | 1967-09-22 | A procedure for the preparation of new derivatives of 1-phenyl-2-aminoetanol. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES0345365A ES345365A1 (en) | 1967-09-22 | 1967-09-22 | A procedure for the preparation of new derivatives of 1-phenyl-2-aminoetanol. (Machine-translation by Google Translate, not legally binding) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES345365A1 true ES345365A1 (en) | 1969-02-01 |
Family
ID=59520683
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0345365A Expired ES345365A1 (en) | 1967-09-22 | 1967-09-22 | A procedure for the preparation of new derivatives of 1-phenyl-2-aminoetanol. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES345365A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012032546A2 (en) | 2010-09-08 | 2012-03-15 | Cadila Healthcare Limited | Process for the preparation of salmeterol and its intermediates |
-
1967
- 1967-09-22 ES ES0345365A patent/ES345365A1/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012032546A2 (en) | 2010-09-08 | 2012-03-15 | Cadila Healthcare Limited | Process for the preparation of salmeterol and its intermediates |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19881117 |