ES8205125A1 - Un procedimiento para la preparacion de una composicion farmaceutica de cesion sostenida de nicardipina o su base. - Google Patents

Un procedimiento para la preparacion de una composicion farmaceutica de cesion sostenida de nicardipina o su base.

Info

Publication number
ES8205125A1
ES8205125A1 ES499854A ES499854A ES8205125A1 ES 8205125 A1 ES8205125 A1 ES 8205125A1 ES 499854 A ES499854 A ES 499854A ES 499854 A ES499854 A ES 499854A ES 8205125 A1 ES8205125 A1 ES 8205125A1
Authority
ES
Spain
Prior art keywords
nicardipine
salt
lasting
ball mill
amorphous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES499854A
Other languages
English (en)
Spanish (es)
Other versions
ES499854A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=12471924&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8205125(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of ES499854A0 publication Critical patent/ES499854A0/es
Publication of ES8205125A1 publication Critical patent/ES8205125A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
ES499854A 1980-03-22 1981-02-26 Un procedimiento para la preparacion de una composicion farmaceutica de cesion sostenida de nicardipina o su base. Expired ES8205125A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3651480A JPS5948810B2 (ja) 1980-03-22 1980-03-22 ニカルジピン持続性製剤用組成物

Publications (2)

Publication Number Publication Date
ES499854A0 ES499854A0 (es) 1982-06-01
ES8205125A1 true ES8205125A1 (es) 1982-06-01

Family

ID=12471924

Family Applications (1)

Application Number Title Priority Date Filing Date
ES499854A Expired ES8205125A1 (es) 1980-03-22 1981-02-26 Un procedimiento para la preparacion de una composicion farmaceutica de cesion sostenida de nicardipina o su base.

Country Status (3)

Country Link
JP (1) JPS5948810B2 (enExample)
ES (1) ES8205125A1 (enExample)
FR (1) FR2489146A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58177916A (ja) * 1982-04-13 1983-10-18 Kowa Co 外用剤
FR2525108B1 (fr) * 1982-04-19 1989-05-12 Elan Corp Ltd Medicaments a haut degre de solubilite et procede pour leur obtention
JPS60259427A (ja) * 1984-06-05 1985-12-21 Ikegai Corp 二軸押出機
JPS618A (ja) * 1984-06-09 1986-01-06 Sawai Seiyaku Kk ニフエジピン含有製剤
YU45837B (sh) * 1988-01-18 1992-07-20 LEK TOVARNA FARMACEVTSKIH IN KEMIČKIH IZDELKOV d.d. Postopek za pripravo novega inkluzijskega kompleksa nikardipina oz. njegovega hidroklorida z beta-ciklodekstrinom
DE3814532A1 (de) * 1988-04-29 1989-11-09 Bayer Ag Dhp-retard-zubereitung
DE60039802D1 (de) * 1999-02-10 2008-09-25 Pfizer Prod Inc Vorrichtung mit matrixgesteuerter Wirkstofffreisetzung
ITMI20021074A1 (it) * 2002-05-20 2003-11-20 Actimex S R L Composizione ternaria comprendente una sostanza attiva e processo di comacinazione per la sua preparazione
TW201613579A (en) 2014-06-24 2016-04-16 Astellas Pharma Inc Pharmaceutical composition for oral administration

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL301747A (enExample) * 1962-12-14
FR2218107A1 (en) * 1973-02-20 1974-09-13 Yamanouchi Pharma Co Ltd Amino alkyl 2,6-dialkyl-4-aryl-1,4 dihydropyridine-3, carboxylates - useful as cerebral vasodilators and musculotropic spasmolytic agents
JPS5132719A (en) * 1974-09-13 1976-03-19 Yoshinobu Nakai Iyakuhinnoshorihoho
GB1579818A (en) * 1977-06-07 1980-11-26 Yamanouchi Pharma Co Ltd Nifedipine-containing solid preparation composition

Also Published As

Publication number Publication date
FR2489146B1 (enExample) 1984-12-21
ES499854A0 (es) 1982-06-01
JPS5948810B2 (ja) 1984-11-29
FR2489146A1 (fr) 1982-03-05
JPS56133217A (en) 1981-10-19

Similar Documents

Publication Publication Date Title
JPS55301A (en) 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
DE2967573D1 (en) Use of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridin-3-beta-methoxy ethylester-5-isopropylester for the preparation of cerebrally active drugs
NZ236581A (en) 3-amino piperidine derivatives, analogues and pharmaceutical compositions
FI890238A0 (fi) Galenska kompositioner med programmerad frigoering av aktivt aemne.
ES8205125A1 (es) Un procedimiento para la preparacion de una composicion farmaceutica de cesion sostenida de nicardipina o su base.
PT78611B (en) Process to prepare a two-phase pharmaceutical composition with niphedypine <dimethylic acid esther 1,4-di-hydro-2,6-dimethyl- 4-(2 nitrophenyl)-3,5-pyridine-dicarboxilic> in non-crystallin e and crystalline forms
DK0993304T3 (da) Farmaceutisk sammensætning med forstærket antitumorvirkning og/eller reducerede bivirkninger, indeholdende et antitumormiddel og et hydroxamsyrederivat
IL69095A0 (en) 9-(2-hydroxyethoxymethyl)guanine derivatives,their preparation and pharmaceutical compositions containing them
RU94035739A (ru) Фармацевтическая композиция, содержащая нифедипин, и способ ее получения
NZ226845A (en) 2', 3'-dideoxy-2'-fluoronucleosides; pharmaceutical compositions and processes for their preparation
IL104158A (en) 4, 13-dioxabicyclo £8.2.1| tridecenone compounds and pharmaceutical compositions containing them
EP0197488A3 (en) 1,4-Dihydropyiridine derivative, a process for preparing the same, a pharmaceutical composition as well as the use thereof
WO1991018599A3 (de) 1,4-dihydropyridine zur anwendung bei der überwindung von arzneimittelresistenzen
IL79118A0 (en) 1,4-dihydropyridines,their preparation and pharmaceutical compositions containing them
FR2681863B1 (fr) Solution de sparfloxacine sa preparation et sel la constituant.
IL74800A (en) Esters of 4-aryl-1,4,5,7-tetrahydro-5-oxothieno(3,4-b)-pyridine-3-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
UA27719C2 (uk) Ефіри 2,6-диметил-1,4-дигідропіридин-3-карбонової кислоти, що є блокаторами кальцієвих каналів, спосіб їх одержання та фармацевтична композиція
NO177484C (no) Fremgangsmåte for fremstilling av et farmasöytisk preparat i form av myke kapsler
KR930002316A (ko) N-알킬화 1,4-디하이드로피리 딘디카르복실산 에스테르
NZ229023A (en) 1,1-dioxo-cephem-4-carbothiolic acid derivatives, pharmaceutical compositions and methods of preparation
ES8708211A1 (es) Un procedimiento para la preparacion de nuevos derivados de 4-(fenil sustituido)-1,4-dihidropiridina.
ES8801543A1 (es) Procedimiento para la preparacion de derivados de 1,4-dihidropiridina
DE59206868D1 (de) Pharmazeutische Zubereitungen mit einer speziellen Kristallmodifikation des 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridindicarbonsäure-isopropyl-(2-methoxyethyl)-esters
OA08854A (fr) Nouveaux dérivés du spiro (4,5) décane, leur procédé de préparation et les compositions pharmaceutiques les renfermant.
AU588414B2 (en) Methionine-substituted 1, 4-dihydropyridines, process for the preparation and their use